Induction of a local and systemic immune response using cholera toxin as vehicle to deliver antigen in the lamina propria of the chicken intestine

Veterinary Immunology and Immunopathology

Volumn 62, Issue 3, 1998, Pages 261-272

  Vervelde, Lonneke ^a   Janse, E Marga ^a   Vermeulen, Arno N ^b   Jeurissen, Suzan H M ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b INTERVET INTERNATIONAL BV   (Netherlands)

Author keywords

Adjuvant; Chicken; Cholera toxin; Intra intestinal vaccination; Mucosal immunity

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CHOLERA TOXIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CECUM; CHICKEN; CONTROLLED STUDY; EIMERIA; IMMUNOSTIMULATION; INTESTINE MUCOSA; LAMINA PROPRIA; LYMPHOCYTE PROLIFERATION; MUCOSAL IMMUNITY; NONHUMAN; T LYMPHOCYTE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, PROTOZOAN; ANTIBODY FORMATION; ANTIGENS, PROTOZOAN; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CECUM; CHICKENS; CHOLERA TOXIN; DRUG CARRIERS; EIMERIA; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNITY, MUCOSAL; IMMUNIZATION; IMMUNOENZYME TECHNIQUES; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTESTINAL MUCOSA; RECOMBINANT PROTEINS;

ANIMALIA; EIMERIA; GALLUS GALLUS;

EID: 0032537109     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2427(97)00171-2     Document Type: Article

References (26)

1. Bowen J.C., Nair S.K., Reddy R., Rouse B.T. Cholera toxin acts as a potent adjuvant for the induction of cytotoxic T-lymphocyte responses with non-replicating antigens. Immunology. 81:1994;338-342.
2. Chen C.-L.H., Ager L.L., Gartland G.L., Cooper M.D. Identification of a T3/T-cell receptor complex in chickens. J. Exp. Med. 164:1986;375-380.
3. Cihak J., Löms Ziegler-Heitbrock H.W., Trainer H., Schranner I., Merkenschlager M., Lösch U. Characterization and functional properties of a novel monoclonal antibody which identifies a T-cell receptor in chickens. Eur. J. Immunol. 18:1988;533-537.
4. Elson C.O., Ealding W. Cholera toxin feeding did not induce oral tolerance in mice and abrogated oral tolerance to an unrelated protein antigen. J. Immunol. 133:1984;2892-2897.
5. Hoshi S., Nakamura T., Nunoya T., Ueda S. Induction of protective immunity in chickens orally immunized with inactivated infectious bursal disease virus. Vaccine. 13:1995;245-252.
6. Jenkins P.G., Wrathmell A.B., Harris J.E., Pulsford A.L. The effects of different adjuvants on intestinal antigen absorption and subsequent immune responses of the tilapian Oreochromis mossambicus. Fish Shellfish Immunol. 4:1994;167-177.
7. Jeurissen S.H.M., Janse E.M., Koch G., de Boer G.F. The monoclonal antibody CVI-ChNL-68.1 recognizes cells of the monocyte-macrophage lineage in chickens. Dev. Comp. Immunol. 12:1988;855-864.
8. Jeurissen S.H.M., Janse E.M., Ekino S., Nieuwenhuis P., Koch G., de Boer G.F. Monoclonal antibodies as probes for defining cellular subsets in the bone marrow, thymus, bursa of Fabricius, and spleen of the chicken. Vet. Immunol. Immunopathol. 19:1988;225-238.
9. Jeurissen S.H.M., Vervelde L., Janse E.M. Structure and function of lymphoid tissues of the chicken. Poultry Sci. Rev. 5:1994;183-207.
10. Liang X., Lamm M.E., Nedrud J.G. Cholera toxin as a mucosal adjuvant: glutaraldehyde treatment dissociates adjuvanticity from toxicity. J. Immunol. 143:1989;484-490.
11. Long P.L., Joyner L.P., Millard B.J., Norton C.C. A guide to laboratory techniques in the study and diagnosis of avian coccidiosis. Folia Vet. Lat. 6:1976;201-217.
12. Lycke N., Holmgren J. Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens. Immunology. 59:1986;301-308.
13. Lycke N., Karlsson U., Sjölander A., Magnusson K.-E. The adjuvant action of cholera toxin is associated with an increased intestinal permeability for luminal antigens. Scand. J. Immunol. 33:1991;691-698.
14. Meinersmann R.J., Porter R.E. Jr. Effect of Vibrio cholerae toxin on oral immunization of chickens. Avian Dis. 37:1993;427-432.
15. Michalek, S.M., Eldridge, J.H., Curtiss, R., III, Rosenthal, K.L., 1994. Antigen delivery Systems: New approaches to mucosal immunizations. In: Ogra, P.L., Strober, W., Mestecky, J., McGhee, J.R., Lamm, M.E., Bienenstock, J. (Eds.), Handbook of Mucosal Immunology, Academic Press, New York, pp. 373-390.
16. Middlebrook J.L., Dorland R.B. Bacterial toxins: cellular mechanisms of action. Microbiol. Rev. 48:1984;199-221.
17. Paramithiotis E., Tkalec L., Ratcliffe M.J.H. High levels of CD45 are coordinately expressed with CD4 and CD8 on avian thymocytes. J. Immunol. 147:1991;3710-3717.
18. Persat F., Bouhours J.F., Petavy A.F., Mojon M. Gangliosides of Echinococcus multilocularis metacestodes. Biochim. Biophys. Acta. 1225:1994;297-303.
19. Sowder J.T., Chen C.-L.H., Ager L.L., Chan M.M., Cooper M.D. A large subpopulation of avian T cells express a homologue of the mammalian Tγδ receptor. J. Exp. Med. 167:1988;315-322.
20. Stok W., Van der Heijden P.J., Bianchi A.T.J. Conversion of orally induced suppression of the mucosal immune response to ovalbumin into stimulation by conjugating ovalbumin to cholera toxin or its B subunit. Vaccine. 12:1994;521-5526.
21. Takada A., Kida H. Protective immune response of chickens against Newcastle disease, induced by the intranasal vaccination with inactivated virus. Vet. Microbiol. 50:1996;17-25.
22. Tregaskes C.A., Kong F.-K., Paramithiotis E., Chen C.-L.H., Ratcliffe M.J.H., Davison T.F., Young J.R. Identification and analysis of the expression of CD8αβ and CD8αα isoforms in chickens reveals a major TCR-γδ CD8αβ subset of intestinal intraepithelial lymphocytes. J. Immunol. 154:1995;4485-4494.
23. Van der Heijden P.J., Bianchi A.T.J., Dol M., Pals J.W., Stok W., Bokhout B.A. Manipulation of intestinal immune responses against ovalbumin by cholera toxin and its B subunit in mice. Immunology. 72:1991;89-93.
24. Vermeulen A.N., Kok J.J., Van den Boogaart P., Dijkema R., Claessens J.A.J. Eimeria refractile body proteins contain two potentially functional characteristics: transhydrogenase and carbohydrate transport. FEMS Microbiol. Lett. 10:1993;223-230.
25. Vervelde L., Vermeulen A.N., Jeurisssen S.H.M. In situ immunocytochemical detection of cells containing antibodies specific for Eimeria tenella antigens. J. Immunol. Meth. 151:1992;191-199.
26. White R.G., French V.I., Stark J.M. A study of the localization of a protein antigen in the chicken spleen and its relation to the formation of germinal centers. J. Med. Microbiol. 3:1970;65-83.