A new way to tert-Butyl [(4R,6R)-6-aminoethyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate, a key intermediate of atorvastatin synthesis

Synthetic Communications

Volumn 33, Issue 13, 2003, Pages 2275-2283

  Rádl, Stanislav ^a  

^a Research Institute of Pharmacy and Biochemistry Prague   (Czech Republic)

Author keywords

Atorvastatin; Henry reaction; Swern oxidation; Synthesis

Indexed keywords

ACETIC ACID DERIVATIVE; ATORVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NITRO DERIVATIVE; NITROALDOL; NITROMETHANE; SODIUM BOROHYDRIDE; TERT BUTYL(2,2 DIMETHYL 6 NITROETHYL 1,3 DIOXAN 4 YL)ACETATE; TERT BUTYL(6 AMINOETHYL 2,2 DIMETHYL 1,3 DIOXAN 4 YL)ACETATE; TERT BUTYL(6 FORMYL 2,2 DIMETHYL 1,3 DIOXAN 4 YL)ACETATE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; DRUG SYNTHESIS; HYDROGENATION; REDUCTION;

EID: 17944402728     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1081/SCC-120021507     Document Type: Article

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