Wegener's granulomatosis: Inflammatory cells and markers of repair and fibrosis in renal biopsies: A clinicopathological study

Scandinavian Journal of Urology and Nephrology

Volumn 35, Issue 5, 2001, Pages 401-410

  Aasarod K ^a   Bostad, L ^a   Hammerstrom J ^a   Jorstad S ^a   Iversen, B M ^a  

^a TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

Author keywords

Lymphocytes; Macrophages; Myofibroblasts; Renal biopsy; Renal function; Vimentin; Wegener's granulomatosis

Indexed keywords

CD8 ANTIGEN; CREATININE; VIMENTIN;

ADOLESCENT; ADULT; AGED; ARTICLE; B LYMPHOCYTE; CELL INFILTRATION; CONTROLLED STUDY; DISEASE MARKER; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; INFLAMMATORY CELL; KIDNEY BIOPSY; KIDNEY FIBROSIS; LEYDIG CELL; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MYOFIBROBLAST; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; TISSUE REPAIR; WEGENER GRANULOMATOSIS;

ACTINS; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD; BIOLOGICAL MARKERS; BIOPSY; CREATININE; FEMALE; FIBROSIS; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KIDNEY; MALE; MIDDLE AGED; PROGNOSIS; SEVERITY OF ILLNESS INDEX; VIMENTIN; WEGENER GRANULOMATOSIS;

EID: 17944375121     PISSN: 00365599     EISSN: None     Source Type: Journal    
DOI: 10.1080/003655901753224477     Document Type: Article

References (58)

1. Wegener granulomatosis: An analysis of 158 patients
2. Relapse rate, renal survival, and cancer morbidity in patients with Wegener's granulomatosis or microscopic polyangiitis with renal involvement
3. Wegener's granulomatosis: Clinical course in 108 patients with renal involvement
4. Wegener's granulomatosis - Clinical-pathologic correlations and long-term course
5. Determinants of renal outcome in anti-myeloperoxidase-associated necrotizing crescentic glomerulonephritis
6. Wegener's granulomatosis with renal involvement: Patient survival and correlations between initial renal function, renal histology, therapy and renal outcome
7. Clinical features and outcome in patients with glomerulonephritis and antineutrophil cytoplasmic autoantibodies
8. The crucial role of renal biopsy in the management of ANCA-associated renal vasculitis
9. Kidney biopsy as a predictor for renal outcome in ANCA-associated necrotizing glomerulonephritis
10. Renal histopathology and clinical course in 94 patients with Wegener's granulomatosis
11. Compassionate treatment of Wegener's granulomatosis with rabbit anti-thymocyte globulin
12. Interferon-alpha treatment of four patients with the Churg-Strauss syndrome
13. Mycophenolate mofetil for maintenance therapy of Wegener's granulomatosis and microscopic polyangiitis: A pilot study in 11 patients with renal involvement
14. Intravenous immunoglobulin for ANCAassociated systemic vasculitis with persistent disease activity
15. Evidence for delayed-type hypersensitivity mechanisms in glomerular crescent formation
16. Myofibroblast phenotypes expression in experimental renal scarring
17. The biology of the myofibroblast
18. Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
19. Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells
20. The American College of Rheumatology 1990 criteria for the classification of Wegener's granulomatosis
21. Comparing groups - Continuous data
22. Diffuse crescentic glomerulonephritis
23. The macrophage in human rapidly progressive glomerulonephritis
24. Macrophages in renal injury
25. Glomerular monocyte-macrophage features in ANCA-positive renal vasculitis and cryoglobulinemic nephritis
26. Secretory products of macrophages
27. Progression of renal damage in human glomerulonephritides: Is there sleight of hand in winning the game?
28. Hapten-specific cellular immune response producing glomerular injury
29. Effect of CTLA-4 chimeric protein on rat autoimmune anti-glomerular basement membrane glomerulonephritis
30. T-cells and macrophages in rapidly progressive glomerulonephritis: Clinicopathologic correlations
31. Participation of cell-mediated immunity in deposition of fibrin in glomerulonephritis
32. T and B cell responses to neutrophil cytoplasmic antigens in systemic vasculitis
33. T cell reactivity to proteinase 3 and myeloperoxidase in patients with Wegener's granulomatosis (WG)
34. T cell activation in patients with ANCAassociated vasculitis: Inefficient immune suppression by therapy
35. Crescentic glomerulonephritis in CD4- and CD8-deficient mice. Requirement for CD4 but not CD8 cells
36. Depletion of CD8 positive cells in nephrotoxic serum nephritis of WKY rats
37. Crucial role of CD8-positive lymphocytes in glomerular expression of ICAM-I and cytokines in crescentic glomerulonephritis of WKY rats
38. + T-cell subsets in Wegener's granulomatosis
39. Reduced CD4-CD8 T cell ratios in patients with Wegener's granulomatosis
40. Costimulatory molecules in Wegener's granulomatosis (WG): Lack of expression of CD28 and preferential up-regulation of its ligands B7-1 (CD80) and B7-2 (CD86) on T cells
41. Intraglomerular and interstitial leukocyte infiltration, adhesion molecules, and interleukin-I alpha expression in 15 cases of antineutrophil cytoplasmic autoantibody-associated renal vasculitis
42. Necrotizing-crescentic glomerulonephritis in ANCA-associated vasculitis: The role of monocytes
43. Crescentic glomerulonephritis
44. Sequential studies of glomerular crescem formation in rats with antiglomerular basement membrane-induced glomerulonephritis and the role of coagulation factors
45. Relationship between the integrity of Bowman's capsule and the composition of cellular crescents in human crescentic glomerulonephritis
46. Consequences of glomerular injury. Glomerular crescent formation
47. Involvement of activated periglomerular leukocytes in the rupture of Bowman's capsule and glomerular crescent progression in experimental glomerulonephritis
48. Transforming growth factor-beta production in antiglomerular basement membrane disease in the rabbit
49. Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis. Alpha-smooth muscle actin is a marker of mesangial cell proliferation
50. Enhanced expression of "muscle-specific" actin in glomerulonephritis
51. Myofibroblasts and the progression of crescentic glomerulonephritis
52. Hyperplasia, hypertrophy, and phenotypic alterations in the distal nephron after acute proximal tubular injury in the rat
53. Molecules involved in T-cell costimulation
54. The B7 and CD28 receptor families
55. Interleukin-1 receptor antagonist halts the progression of established crescentic glomerulonephritis in the rat
56. Suppression of experimental glomerulonephritis by antiserum against transforming growth factor beta 1
57. Natural inhibitor of transforming growth factor-beta protects against scarring in experimental kidney disease
58. Mycophenolate mofetil reduces myofibroblast infiltration and collagen III deposition in rat remnant kidney