Complex gel permeation assays for screening combinatorial libraries

Journal of Biomolecular Screening

Volumn 6, Issue 5, 2001, Pages 313-323

  Schurdak, Mark E ^a   Voorbach, Martin J ^a   Gao, Lan ^a   Cheng, Xueheng ^a   Comess, Kenneth M ^a   Rottinghaus, Susan M ^a   Warrior, Usha ^a   Truong, Hoa N ^a   Burns, David J ^a   Beutel, Bruce A ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; INTERLEUKIN 8; PROTEIN INHIBITOR; SIALIDASE INHIBITOR; UROKINASE; UROKINASE RECEPTOR;

ANALYTIC METHOD; ARTICLE; COMBINATORIAL LIBRARY; DRUG SCREENING; ENZYME ASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL PERMEATION CHROMATOGRAPHY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

CHROMATOGRAPHY, GEL; COMBINATORIAL CHEMISTRY TECHNIQUES; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; INTERLEUKIN-8; NEURAMINIDASE; ORTHOMYXOVIRIDAE; PROTEIN BINDING; RECEPTORS, CELL SURFACE; RECEPTORS, INTERLEUKIN-8A; URINARY PLASMINOGEN ACTIVATOR;

EID: 17944366722     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1089/108705701753200527     Document Type: Article

References (18)

1. Discovery and identification of lead compounds from combinatorial mixtures
2. Strategies for screening combinatorial libraries
3. Approaches and technologies for screening large combinatorial libraries
4. Creation and functional screening of a multi-use peptide library
5. Combinatorial diffusion assay used to identify topically active melanocyte-stimulating hormone receptor antagonists
6. High-volume cellular screening for anticancer agents with combinatorial chemical libraries: A new methodology
7. New technologies for high-throughput screening
8. History of combinatorial chemistry
9. Molecular diversity and libraries of structures: Synthesis and screening
10. The "one-bead-one-compound" combinatorial library method
11. A single-bead decode strategy using electrospray ionization mass spectrometry and a new photolabile linker: 3-amino-3-(2-nitrophenyl)propionic acid
12. Combinatorial library analysis using Fourier transform mass spectrometry (FTMS and tandem mass spectrometry (MS/MS))
13. Designing, synthesis, and structural analysis of influenza neuraminidase inhibitors containing pyrrolidine cores
14. Resistance of influenza viruses to neuraminidase inhibitors - A review
15. A paradigm for drug discovery employing encoded combinatorial libraries
16. Well-less, gel permeation format for ultra-high throughput screening
17. More compounds tested with less automation