Effects of Intrauterine Food Restriction and Long-Term Dietary Supplementation with l-Arginine on Age-Related Changes in Renal Function and Structure of Rats

Pediatric Research

Volumn 57, Issue 5, 2005, Pages 724-731

  Gil, Frida Zaladek ^a   Lucas, Sandra Regina R ^a   Gomes, Guiomar Nascimento ^a   Cavanal, Maria De FáTima ^a   Coimbra, Terezila Machado ^b  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; DESMIN; FIBRONECTIN;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MEASUREMENT; CONTROLLED STUDY; DIET RESTRICTION; DIET SUPPLEMENTATION; FUNCTIONAL ASSESSMENT; GLOMERULOSCLEROSIS; GLOMERULUS FILTRATION RATE; GLOMERULUS INJURY; HISTOPATHOLOGY; HYPERTENSION; IMMUNOHISTOCHEMISTRY; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY STRUCTURE; MALE; MATERNAL NUTRITION; NEPHRON; NONHUMAN; ONSET AGE; PARAMETER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA; RAT; RAT STRAIN;

ACTINS; AGING; ANIMALS; ARGININE; BLOOD PRESSURE; DIETARY SUPPLEMENTS; FEMALE; FETAL GROWTH RETARDATION; FIBRONECTINS; FOOD DEPRIVATION; GLOMERULAR FILTRATION RATE; GLOMERULONEPHRITIS; IMMUNOHISTOCHEMISTRY; KIDNEY; PLACENTAL INSUFFICIENCY; PREGNANCY; PREGNANCY, ANIMAL; PRENATAL EXPOSURE DELAYED EFFECTS; PROTEINURIA; RATS; RATS, WISTAR; TIME FACTORS; WEIGHT GAIN;

EID: 17844400106     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1203/01.PDR.0000159514.06939.7E     Document Type: Article

References (50)

1. Barker DJ, Osmond C, Golding J, Kuh D, Wadsworth ME 1989 Growth in utero, blood pressure in childhood and adult life and mortality from cardiovascular disease. BMJ 298:564-567.
2. Barker DJ 1995 Fetal origins of coronary heart disease. BMJ 311:171-174.
3. Campbell DM, Hall MH, Barker DJ, Cross J, Shiell AW, Godfrey KM 1996 Diet in pregnancy and the offspring’s blood pressure 40 years later. Br J Obstet Gynaecol 103:273-280.
4. Barker DJ 1988 In utero programming of chronic disease. Clin Sci (Lond) 95:115-128.
5. Lucas SR, Zaladek-Gil F, Costa-Silva VL, Miraglia SM 1991 Function and morphometric evaluation of intrauterine undernutrition on kidney development of the progeny. Braz J Med Biol Res 24:967-970.
6. Lucas SRR, Costa Silva VL, Miraglia SM, Zaladek Gil F 1997 Functional and morphometric evaluation of offspring kidney after intrauterine undernutrition. Pediatr Nephrol 11:719-723.
7. Merlet-Benichou C, Gilbert T, Muffat-Joly M, Lelievre-Pegorier M, Leroy B 1994 Intrauterine growth retardation leads to a permanent nephron deficit in the rat. Pediatr Nephrol 8:175-180.
8. Welham SJ, Wade A, Woolf AS 2002 Protein restriction in pregnancy is associated with increased apoptosis of mesenchymal cells at the start of rat metanephrogenesis. Kidney Int 61:1231-1242.
9. Langley-Evans SC, Gardner DS, Welham SJ 1998 Intrauterine programming of cardiovascular disease by maternal nutritional status. Nutrition 14:39-47.
10. Woods LL, Ingelfinger JR, Nyengaard JR, Rasch R 2001 Maternal protein restriction suppresses the newborn renin-angiotensin system and programs adult hypertension in rats. Pediatr Res 49:460-467.
11. Manning J, Beutler K, Knepper MA, Vehaskari VM 2002 Upregulation of renal BSC1 and TSC in prenatally programmed hypertension. Am J Physiol Renal Physiol 283:F202-F206.
12. Anderson S, Brenner BM 1986 Effects of aging on the renal glomerulus. Am J Med 80:435-442.
13. Melk A, Halloran PF 2001 Cell senescence and its implications for nephrology. J Am Soc Nephrol 12:385-393.
14. Couser WG, Stilmant MM 1975 Mesangial lesions and focal glomerular sclerosis in the aging rat. Lab Invest 33:491-501.
15. Lucas SRR, Miraglia SM, Zaladek Gil F, Coimbra TM 2001 Intrauterine food restriction as a determinant of nephrosclerosis. Am J Kidney Dis 37:467-476.
16. Alves GM, Barão MA, Odo LN, Nascimento Gomes G, Franco Mdo C, Nigro D, Lucas SR, Laurindo FR, Brandizzi LI, Zaladek Gil F 2002 L-Arginine effects on blood pressure and renal function of intrauterine restricted rats. Pediatr Nephrol 17:856-62.
17. Reyes AA, Purkerson ML, Karl I, Klahr S 1992 Dietary supplementation with L-arginine ameliorates the progression of renal disease in rats with subtotal nephrectomy. Am J Kidney Dis 20:168-176.
18. Reyes AA, Karl IE, Kissane J, Klahr S 1993 L-arginine administration prevents glomerular hyperfiltration and decreases proteinuria in diabetic rats. J Am Soc Nephrol 41:1039-1045.
19. Reckelhoff JF, Kellum JÁ Jr, Racusen LC, Hildebrandt DA 1997 Long-term dietary supplementation with L-arginine prevents age-related reduction in renal function. Am J Physiol 272:R1768-R1774.
20. Boger RH, Bode-Boger SM, Mugge A, Kienke S, Brandes R, Dwenger A, Frolich JC 1995 Supplementation of hypercholesterolaemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production. Atherosclerosis 117:273-284.
21. Brenner BM, Garcia DL, Anderson S 1988 Glomeruli and blood pressure. Less of one, more the other? Am J Hypertens 1:335-347.
22. Klag MJ, Whelton PK, Randall BL, Neaton JD, Brancati FL, Ford CE, Shulman NB, Stamler J 1996 Blood pressure and end-stage renal disease in men. N Engl J Med 334:13-18.
23. Marcantoni C, Jafar TH, Oldrizzi L, Levey AS, Maschio G 2000 The role of systemic hypertension in the progression of nondiabetic renal disease. Kidney Int Suppl 75:S44-S48.
24. De Carmo Pinho Franco M, Nigro D, Fortes ZB, Tostes RC, Carvalho MH, Lucas SR, Gomes GN, Coimbra TM, Gil FZ 2003 Intrauterine undernutrition-renal and vascular origin of hypertension. Cardiovasc Res 60:228-234.
25. Flores-Mendonza I, Mello Aires M, Malnic G 1979 Effect of furosemide on urinary acidification during alterations of acid-base equilibrium in the rat. J Bras Nefrol 1:51-58.
26. Smith HW, Finkelstein N, Aliminosa L, Grawford B, Graber M 1945 The renal clearances of substituted hippuric acid derivatives and other aromatic acids in dog and man. J Clin Invest 24:388.
27. Connerty VH, Angles MD, Briggs R, Eaton EH 1957 Determination of urinary ammonia (nitrogen) by means of direct nesslerization. Am J Clin Pathol 28:634-638.
28. Shih W, Hines WH, Nielson EG 1988 Effects of cyclosporin A on the development of immune-mediated interstitial nephritis. Kidney Int 33:1113-1118.
29. Johnson RJ, Garcia RL, Pritzl P, Alpers CE 1990 Platelets mediate glomerular cell proliferation in immune complex nephritis induced by anti-mesangial cell antibodies in the rat. Am J Pathol 136:369-374.
30. Kliem V, Johnson RJ, Alpers CE, Yoshimura A, Couser WG, Koch KM, Floege J 1996 Mechanisms involved in the pathogenesis of tubulointerstitial fibrosis in 5/6-nephrectomized rats. Kidney Int 49:666-678.
31. Coimbra TM, Janssen U, Gröne HJ, Ostendorf T, Kunter U, Schmidt H, Brabant G, Floege J 2000 Early events leading to renal injury in obese Zucker (fatty) rats with type II diabetes. Kidney Int 57:167-182.
32. Gröne HJ, Weber K, Gröne E, Helmchen U, Osborn M 1987 Coexpression of keratin and vimentin in damaged and regenerating tubular epithelia of the Kidney. Am J Pathol 129:1-8.
33. Johnson RJ, Iida H, Alpers CE, Majesky MW, Schwartz SM, Pritzl P, Gordon K, Gown AM 1991 Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis. Alpha-smooth muscle actin is a marker of mesangial cell proliferation. J Clin Invest 87:847-858.
34. Alpers CE, Hudkins KL, Floege J, Johnson RJ 1994 Human renal cortical interstitial cells with some features of smooth muscle cells participate in tubulointerstitial and crescentic glomerular injury. J Am Soc Nephrol 5:201-209.
35. Floege J, Hackmann B, Kliem V, Kriz W, Alpers CE, Johnson RJ, Kuhn KW, Koch KM, Brunkhorst R 1997 Age-related glomerulosclerosis and interstitial fibrosis in Milan normotensive rats: a podocyte disease. Kidney Int 51:230-243.
36. Floege J, Alpers CE, Sage EH, Pritzl P, Gordon K, Johnson RJ, Couser WG 1992 Markers of complement-dependent and complement-independent glomerular visceral epithelial cell injury in vivo. Expression of antiadhesive proteins and cytoskeletal changes. Lab Invest 67:486-497.
37. Griffin KA, Picken MM, Churchill M, Churchill P, Bidani AK 2000 Functional and structural correlates of glomerulosclerosis after renal mass reduction in the rat. J Am Soc Nephrol 11:497-506.
38. Moritz KM, Wintour EM, Dodic M 2002 Fetal uninephrectomy leads to prenatal hypertension and compromised renal function. Hypertension 39:1071-1076.
39. Zatz R, Baylis C 1998 Chronic nitric oxide inhibition model six years on. Hypertension 32:958-964.
40. Ono H, Ono Y, Takanohashi A, Matsuoka H, Frohlich ED 2001 Apoptosis and glomerular injury after prolonged nitric oxide synthase inhibition in spontaneously hypertensive rats. Hypertension 38:1300-1306.
41. Vaziri ND, Wang XQ, Ni ZN, Kivlighn S, Shahinfar S 2002 Effects of aging and AT-1 receptor blockade on NO synthase expression and renal function in SHR. Biochim Biophys Acta 1592:153-161.
42. Franco Mdo C, Akamine EH, DiMarco GS, Casarini DE, Fortes ZB, Carvalho MH 2003 NADPH oxidase and enhanced superoxide generation in the intrauterine undernourished rats: involvement of the renin-angiotensin system. Cardiovasc Res 59:767-775.
43. Franco Mdo C, Dantas AP, Akamine HE, Kawamoto EM, Fortes ZB, Scavone C, Tostes RC, Carvalho MH, Nigro D 2002 Enhanced oxidative stress as a potential mechanism underlying the programming of hypertension in utero. J Cardivasc Pharmacol 40:501-509.
44. Franco Mdo C, Arruda RM, Dantas AP, Kawamoto EM, Fortes ZB, Scavone C, Carvalho MH, Tostes RC, Nigro D 2002 Intrauterine undernutrition: expression and activity of the endothelial nitric oxide synthase in male and female adult offspring. Cardiovasc Res 56:145-153.
45. Moritz KM, Wintour EM 1999 Functional development of the meso- and metanephros. Pediatr Nephrol 13:171-178.
46. Riser BL, Cortes P, Zhao X, Bernstein J, Dumler F, Narins RG 1992 Intraglomerular pressure and mesangial stretching stimulate extracellular matrix formation in the rat. J Clin Invest 90:1932-1943.
47. Tan D, Cernadas MR, Aragoncillo P, Castilla MA, Alvarez Arroyo MV, López Farre AJ, Casado S, Caramelo C 1998 Role of nitric oxide-related mechanism in renal function in ageing rats. Nephrol Dial Transplant 13:594-601.
48. Arcos MI, Fujihara CK, Sesso A, Almeida Prado EB, de Almeida Prado MJ, de Nucci G, Zatz R 2000 Mechanisms of albuminuria in the chronic nitric oxide inhibition model. Am J Physiol Renal Physiol 279:F1060-F1066.
49. Tolbert EM, Weisstuch J, Feiner HD, Dworkin LD 2000 Onset of glomerular hypertension with aging precedes injury in the spontaneously hypertensive rat. Am J Physiol Renal Physiol 278:F839-F846.
50. Woods LL, Weeks DA, Rasch R 2001 Hypertension after neonatal uninephrectomy in rats precedes glomerular damage. Hypertension 38:337-342.