Onset of glomerular hypertension with aging precedes injury in the spontaneously hypertensive rat

American Journal of Physiology - Renal Physiology

Volumn 278, Issue 5 47-5, 2000, Pages

  Tolbert, Evelyn M ^a   Weisstuch, Joseph ^a   Feiner, Helen D ^a   Dworkin, Lance D ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

Angiotensin II; Endothelin; Glomerular hemodynamics; Nitric oxide

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; GLOMERULOSCLEROSIS; GLOMERULUS FILTRATION RATE; HYPERTENSION; KIDNEY BIOPSY; KIDNEY BLOOD FLOW; NONHUMAN; PRIORITY JOURNAL; RAT; RENOVASCULAR HYPERTENSION; SPONTANEOUSLY HYPERTENSIVE RAT; VASCULAR RESISTANCE;

EID: 0034034405     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.2000.278.5.f839     Document Type: Article

References (43)

1. Allison MEM, Lipman EM, and Gottschalk CW. Hydrostatic pressure in the rat kidney. Am J Physiol 223: 975-983, 1972.
2. Anderson S, Meyer T, Rennke HG, and Brenner BM. Control of glomerular hypertension limits glomerular injury in rats with reduced renal mass. J Clin Invest 76: 612-619, 1985.
3. Anderson S, Rennke HG, and Zatz R. Glomerular adaptations with normal aging and with long-term converting enzyme inhibition in rats. Am J Physiol Renal Fluid Electrolyte Physiol 267: F35-F43, 1994.
4. Arendshorst WJ and Beierwaltes WH. Renal and nephron hemodynamics in spontaneously hypertensive rats. Am J Physiol Renal Fluid Electrolyte Physiol 236: F246-F251, 1979.
5. Azar S, Johnson MA, Scheinman J, Bruno L, and Tobian L. Regulation of glomerular capillary pressure and filtration rate in young Kyoto hypertensive rats. Clin Sci (Oxf) 56: 203-209, 1979.
6. Bauer JH, Reams GP, and Zhen W. The aging hypertensive kidney: pathophysiology and therapeutic options. Am J Med 90: 21S-27S, 1991.
7. Baylis C. Renal responses to acute angiotensin II inhibition and administered angiotensin II in the aging, conscious, chronically catheterized rat. Am J Kidney Dis 22: 842-850, 1993.
8. Baylis C, Deen WM, Myers BD, and Brenner BM. Effects of some vasodilator drugs on transcapillary fluid exchange in renal cortex. Am J Physiol 230: 1148-1158, 1976.
9. Benstein JA, Parker M, Feiner HD, and Dworkin LD. Superiority of salt restriction over diuretics in reducing renal hypertrophy and injury in uninephrectomized SHR. Am J Physiol Renal Fluid Electrolyte Physiol 258: F1675-F1681, 1990.
10. Bloem LJ, Manatunga AK, Tewksbury DA, and Pratt JH. The serum angiotensinogen concentration and variants of the angiotensinogen gene in white and black children. J Clin Invest 95: 948-953, 1995.
11. Brenner BM and Chertow GM. Congenital oligonephropathy and the etiology of adult hypertension and progressive renal injury. Am J Kidney Dis 23: 171-175, 1994.
12. Carmines PK, Morrison TK, and Navar LG. Angiotensin II effects on microvascular diameters of in vitro blood-perfused juxtamedullary nephrons. Am J Physiol Renal Fluid Electrolyte Physiol 251: F610-F618, 1986.
13. 2+ channel blockage on afferent and efferent arteriolar responses to ANG II. Am J Physiol Renal Fluid Electrolyte Physiol 256: F1015-F1020, 1989.
14. Casellas D, Carmines PK, and Navar LG. Microvascular reactivity of in vitro blood-perfused juxtamedullary nephrons from rats. Kidney Int 28: 752-759, 1985.
15. Conger JD and Falk SA. KCl and angiotensin responses in isolated rat renal arterioles: effects of diltiazem and low-calcium medium. Am J Physiol Renal Fluid Electrolyte Physiol 264: F717-F721, 1993.
16. Corman B and Michel J-B. Renin-angiotensin system, converting-enzyme inhibition and kidney function in aging female rats. Am J Physiol Regulatory Integrative Comp Physiol 251: R450-R455, 1986.
17. Dworkin LD and Feiner HD. Glomerular injury in uninephrectomized spontaneously hypertensive rats: a consequence of glomerular capillary hypertension. J Clin Invest 77: 797-809, 1986.
18. Dworkin LD, Feiner HD, and Randazzo J. Glomerular hypertension and injury in desoxycorticosterone-salt rats on antihypertensive therapy. Kidney Int 31: 718-724, 1986.
19. Edwards RM and Aiyar N. Angiotensin II receptor subtypes in the kidney. J Am Soc Nephrol 3: 1643-1652, 1993.
20. Feld LG, Van Liew JB, Galeske RG, and Boyland JW. Selectivity of renal injury and proteinuria in the spontaneously hypertensive rat. Kidney Int 12: 332-343, 1977.
21. Fogo A, Breyer JA, Smith MC, Cleveland WH, Agodoa L, Kirk KA, and Glassock R. Accuracy of the diagnosis of hypertensive nephrosclerosis in African Americans: a report from the African American Study of Kidney Disease (AASK) Trial. AASK Pilot Study Investigators. Kidney Int 51: 244-252, 1997.
22. Fujihara CK, Limongi, DMZP, De Oliveira, HCF, and Zatz R. Absence of focal glomerulosclerosis in aging analbuminemic rats. Am J Physiol Regulatory Integrative Comp Physiol 262: R947-R954, 1992.
23. Hayashi M, Saruta T, Nakamura R, Kitajima W, and Kato E. Effect of aging on single nephron renin content in rats. Kidney Int 34: 17-21, 1988.
24. Hill C, Lateef, AM, Engels, K, Samsell, L, and Baylis C. Basal and stimulated nitric oxide in control of kidney function in the aging rat. Am J Physiol Regulatory Integrative Comp Physiol 272: R1747-R1753, 1997.
25. Ito S, Arima S, Ren YL, Juncos LA, and Carretero OA. Endothelium-derived relaxing factor/nitric oxide modulates angiotensin II action in the isolated microperfused rabbit afferent but not efferent arteriole. J Clin Invest 91: 2012-2019, 1993.
26. Jung FF, Kennefick TM, Ingelfinger JR, Vora JP, and Anderson S. Down-regulation of the intrarenal renin-angiotensin system in the aging rat. J Am Soc Nephrol 5: 1573-1580, 1995.
27. Komatsu K, Frohlich, ED, Ono H, Ono Y, Numabe A, and Willis GW. Glomerular dynamics and morphology of aged spontaneously hypertensive rats: effects of angiotensin-converting enzyme inhibition. Hypertension 25: 207-213, 1995.
28. Mailloux LU, Bellucci AG, Mossey RT, Napolitano B, Moore T, Wilkes BM, and Bluestone PA. Predictors of survival in patients undergoing dialysis. Am J Med 84: 855-862, 1988.
29. Meyer TW, Baboolal K, and Brenner BM. Nephron adaptation to renal injury In: The Kidney, edited by Brenner BM. Philadelphia, PA: Saunders, 1996, p. 2011-2048.
30. Myers BD, Deen, WM, and Brenner BM. Effects of norepinephrine and angiotensin II on the determinants of glomerular ultrafiltration and proximal tubule fluid reabsorption in the rat. Circ Res 37: 101-110, 1975.
31. Parving HH, Jensen HAE, Mogensen CE, and Evrin PE. Increased urinary albumin excretion rate in benign essential hypertension. Lancet 1: 1190-1192, 1974.
32. Pedersen EB and Mogensen CE. Effect of antihypertensive treatment on urinary albumin excretion, glomerular filtration rate and renal plasma flow in patients with essential hypertension. Scand J Clin Lab Invest 36: 231-237, 1976.
33. Reckelhoff JFL. Age-related changes in renal hemodynamics in female rats: role of multiple pregnancy and NO. Am J Physiol Regulatory Integrative Comp Physiol 272: R1985-R1989, 1997.
34. Reckelhoff JFL, Samsell L, Dey R, Racusen L, and Baylis C. The effect of aging on glomerular hemodynamics in the rat. Am J Kidney Dis 20: 70-75, 1992.
35. Sen S, Semby RR, and Bumpus RM. Renin in rats with spontaneous hypertension. Circ Res 31: 876-880, 1972.
36. Steinhausen M, Sterzel B, Fleming JT, Kuhn R, and Weis S. Acute and chronic effects of angiotensin II on the vessels of the split hydronephrotic kidney. Kidney Int Suppl 20: 565-573, 1987.
37. Tank JE, Vora JP, Houghton DC, and Anderson S. Altered renal vascular responses in the aging kidney. Am J Physiol Renal Fluid Electrolyte Physiol 266: F942-F948, 1994.
38. US Renal Data System. USRDS 1998 Annual Report. Bethesda, MD: Natl. Inst. Health, 1998.
39. Viets JW, Deen WM, Troy JL, and Brenner BM. Determination of serum protein concentration in nanoliter blood samples using fluorescamine or 9-phthalaldehyde. Anal Biochem 88: 513-521, 1978.
40. 2 and sodium p-aminohippurate. Science 100: 108, 1944.
41. Weidmann PS, de Myttenaere-Bursztein S, Maxwell MH, and de Lima J. Effect of aging on plasma renin and aldosterone in normal man. Kidney Int 8: 325-333, 1975.
42. Weir MR and Dworkin LD. Antihypertensive drugs, dietary salt, and renal protection: how low should you go and with which therapy? Am J Kidney Dis 32: 1-22, 1998.
43. Zhang X-Z, Qiu, C, and Baylis C. Sensitivity of the segmental renal arterioles to angiotensin II in the aging rat. Mech Ageing Dev 97: 183-192, 1997.