-
1
-
-
17844378640
-
Momentum's winning force
-
January 05
-
Stovall S: Momentum's winning force. BusinessWeek Online (2005) January 05. http://businessweek.com/investor/content/jan2005/pi2005 015_8394_pi039.htm
-
(2005)
BusinessWeek Online
-
-
Stovall, S.1
-
2
-
-
17844407087
-
Merck's arthritis resolution
-
December 31
-
Lagorce A: Merck's arthritis resolution. Forbes.com (2003) December 31. http://www.forbes.com/2003/12/31/cx_al_ 1231mrk.html
-
(2003)
Forbes.com
-
-
Lagorce, A.1
-
3
-
-
17844401919
-
Merck announces voluntary worldwide withdrawal of Vioxx®
-
September 30
-
Merck & Co: Merck announces voluntary worldwide withdrawal of Vioxx®. Press Release (2004) September 30. http://www.vioxx.com/rofecoxib/ vioxx/consumer/index.jsp
-
(2004)
Press Release
-
-
-
6
-
-
17844385979
-
-
US Food and Drug Administration, Rockville, MD, USA
-
Original INDs received calendar years 1986-2004: US Food and Drug Administration, Rockville, MD, USA (2004). http://www.fda.gov /cder/rdmt/Cyindrec.htm
-
(2004)
Original INDs Received Calendar Years 1986-2004
-
-
-
7
-
-
17844411127
-
-
US Food and Drug Administration. Rockville, MD, USA
-
CDER number of NDAs received by calendar year: US Food and Drug Administration. Rockville, MD, USA (2004). http://www.fda.gov/cder/rdmt/ numofndareccy.htm
-
(2004)
CDER Number of NDAs Received by Calendar Year
-
-
-
8
-
-
0346905320
-
The genomics evolution
-
Thayer AM: The genomics evolution. Chem Eng News (2003) 81(49):17-26. Overview detailing the impact of genomics to drug discovery.
-
(2003)
Chem Eng News
, vol.81
, Issue.49
, pp. 17-26
-
-
Thayer, A.M.1
-
9
-
-
17844378129
-
-
US Food and Drug Administration, Rockville, MD, USA
-
CDER new drug and biologic approval reports: US Food and Drug Administration, Rockville, MD, USA (2004). http://www.fda.gov/cder/rdmt/default. htm
-
(2004)
CDER New Drug and Biologic Approval Reports
-
-
-
10
-
-
2942589281
-
Blockbuster challenge
-
Coghlan A: Blockbuster challenge. New Scientist (2004) (2451):54-57. Article which outlines the problems of the blockbuster business model.
-
(2004)
New Scientist
, Issue.2451
, pp. 54-57
-
-
Coghlan, A.1
-
12
-
-
0012990770
-
-
IBM Business Consulting Services, Manchester, UK
-
Arlington S, Barnett S, Davies N, Palo J: Pharma 2010: The threshold of innovation: IBM Business Consulting Services, Manchester, UK (2004). http://www-1.ibm.com/services/us/index.wss/xs/imc/a 1001099 Seminal article detailing the authors' views on targeted treatments.
-
(2004)
Pharma 2010: The Threshold of Innovation
-
-
Arlington, S.1
Barnett, S.2
Davies, N.3
Palo, J.4
-
13
-
-
17844379660
-
The world's best-selling drugs
-
March 16
-
Herper M: The world's best-selling drugs. Forbes.com (2004) March 16. http://www.forbes.com/technology/2004/03/16/cx_mh_0316best selling.html
-
(2004)
Forbes.com
-
-
Herper, M.1
-
14
-
-
17844388770
-
Glaxo seeks cease-fire in 'arms race' in sales
-
February 11
-
Ginsberg T: Glaxo seeks cease-fire in 'arms race' in sales. Philadelphia Inquirer (2005) February 11.
-
(2005)
Philadelphia Inquirer
-
-
Ginsberg, T.1
-
15
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Jänne PA, Lee JC, Tracy S, Greulich H, Gabriel S. Herman P, Kaye FJ, Lindeman N, Boggon TJ. Naoki K et al: EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science (2004) 304(5676):1497-1500.
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Jänne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
Herman, P.7
Kaye, F.J.8
Lindeman, N.9
Boggon, T.J.10
Naoki, K.11
-
16
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, Harris PL, Haserlat SM, Supko JG, Haluska FG, Louis DN et al: Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med (2004) 350(21):2129-2139.
-
(2004)
N Engl J Med
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Haserlat, S.M.8
Supko, J.G.9
Haluska, F.G.10
Louis, D.N.11
-
17
-
-
84952964193
-
Clinical pharmacogenomics: Almost a reality?
-
Filmore D: Clinical pharmacogenomics: Almost a reality? Mod Drug Disc (2004) 7(8):41-44.
-
(2004)
Mod Drug Disc
, vol.7
, Issue.8
, pp. 41-44
-
-
Filmore, D.1
-
18
-
-
17844370449
-
Personalized medicine in cancer: Matching patients and drugs
-
October 28
-
Ruder K: Personalized medicine in cancer: Matching patients and drugs. Genome News Network (2004) October 28. http://www. genomenewsnetwork.org/ articles/2004/10/28/matchingpatients.php?prin t=1
-
(2004)
Genome News Network
-
-
Ruder, K.1
-
19
-
-
0242640305
-
Pharmacogenomics and reducing the frequency of adverse drug events
-
O'Kane DJ, Weinshilboum RM, Moyer TP: Pharmacogenomics and reducing the frequency of adverse drug events. Pharmacogenomics (2003) 4(1):1-4.
-
(2003)
Pharmacogenomics
, vol.4
, Issue.1
, pp. 1-4
-
-
O'Kane, D.J.1
Weinshilboum, R.M.2
Moyer, T.P.3
-
20
-
-
2642570170
-
Moving towards individualized medicine with pharmacogenomics
-
Evans WE, Relling MV: Moving towards individualized medicine with pharmacogenomics. Nature (2004) 429(6990):464-468.
-
(2004)
Nature
, vol.429
, Issue.6990
, pp. 464-468
-
-
Evans, W.E.1
Relling, M.V.2
-
21
-
-
16644402982
-
Accelerating drug discovery: Although the evolution of '-omics' methodologies is still in its infancy, both the pharmaceutical industry and patients could benefit from their implementation in the drug development process
-
Kraljevic S, Stambrook PJ, Pavelic K: Accelerating drug discovery: Although the evolution of '-omics' methodologies is still in its infancy, both the pharmaceutical industry and patients could benefit from their implementation in the drug development process. EMBO Rep (2004) 5(9):837-842.
-
(2004)
EMBO Rep
, vol.5
, Issue.9
, pp. 837-842
-
-
Kraljevic, S.1
Stambrook, P.J.2
Pavelic, K.3
-
22
-
-
17844376971
-
Powering up the pipeline
-
Arlington S, Davies N: Powering up the pipeline. Pharmafocus (2003). http://www.pharmafocus.com/cda/focusH/1,2109.22-0-0-0-focus_ feature_detail-0-74296,00. html An additional article outlining the authors' viewpoints.
-
(2003)
Pharmafocus
-
-
Arlington, S.1
Davies, N.2
-
24
-
-
0004235150
-
-
PricewaterhouseCoopers LLP, New York, NY, USA
-
Pharma 2005: Silicon rally - The race to eR&D: PricewaterhouseCoopers LLP, New York, NY, USA (1999). http://www. pwcglobal.com/gx/eng/about/ind/ pharma/silicon_rally.pdf
-
(1999)
Pharma 2005: Silicon Rally - The Race to ER&D
-
-
-
25
-
-
17644413037
-
Making the most of your discovery data
-
Davies N, Peakman T: Making the most of your discovery data. Drug Disc World (2004) (Spring):17-23.
-
(2004)
Drug Disc World
, Issue.SPRING
, pp. 17-23
-
-
Davies, N.1
Peakman, T.2
-
26
-
-
17844366761
-
Information avalanche: Enterprise content management
-
Atkmson WI: Information avalanche: Enterprise content management. Mod Drug Disc (2004) 7(12):49-50.
-
(2004)
Mod Drug Disc
, vol.7
, Issue.12
, pp. 49-50
-
-
Atkmson, W.I.1
-
28
-
-
4544335467
-
Translation of pharmacogenomics and pharmacogenetics: A regulatory perspective
-
Lesko L, Woodcock J: Translation of pharmacogenomics and pharmacogenetics: A regulatory perspective. Nat Rev Drug Disc (2004) 3:763-769.
-
(2004)
Nat Rev Drug Disc
, vol.3
, pp. 763-769
-
-
Lesko, L.1
Woodcock, J.2
-
29
-
-
17844376125
-
Personalized medicine's bitter pill
-
February
-
Hall SS: Personalized medicine's bitter pill. Technology Review.com (2003) February. http://www.technologyreview.com/articles/03/02/hall0203.asp?p=1
-
(2003)
Technology Review.com
-
-
Hall, S.S.1
|