Brief communication: Hematogenuos dissemination in early lyme disease

Annals of Internal Medicine

Volumn 142, Issue 9, 2005, Pages 751-755

  Wormser, Gary P ^a   McKenna, Donna ^b   Carlin, Jennafer ^b   Nadelman, Robert B ^b   Cavallere, L Frank ^b   Holmgren, Diane ^b   Byrne, Daniel W ^b   Nowakowski, John ^b  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT;

ADULT; ARTICLE; BLOOD CULTURE; BORRELIA BURGDORFERI; CLINICAL FEATURE; CONTROLLED STUDY; ERYTHEMA CHRONICUM MIGRANS; FEMALE; HUMAN; HUMAN TISSUE; LYME DISEASE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SYMPTOMATOLOGY; UNITED STATES; BACTEREMIA; CROSS-SECTIONAL STUDY; ISOLATION AND PURIFICATION; MICROBIOLOGY;

ADULT; BACTEREMIA; BORRELIA BURGDORFERI; CROSS-SECTIONAL STUDIES; HUMANS; LYME DISEASE;

EID: 17844388066     PISSN: 00034819     EISSN: None     Source Type: Journal    
DOI: 10.7326/0003-4819-142-9-200505030-00011     Document Type: Article

References (18)

1. Wormser GP, Liveris D, Nowakowski J, Nadelman RB, Cavaliere LF, McKenna D, et al. Association of specific subtypes of Borrelia burgdorferi with hematogenous dissemination in early Lyme disease. J Infect Dis. 1999;180:720-5.
2. Seinost G, Dykhuizen DE, Dattwyler RJ, Golde WT, Dunn JJ, Wang IN, et al. Four clones of Borrelia burgdorferi sensu stricto cause invasive infection in humans. Infect Immun. 1999;67:3518-24.
3. Lagal V, Postic D, Ruzic-Sabljic E, Baranton G. Genetic diversity among Borrelia strains determined by single-strand conformation polymorphism analysis of the ospC gene and its association with invasiveness. J Clin Microbiol. 2003;41:5059-65.
4. Steere AC, Schoen RT, Taylor E. The clinical evolution of Lyme arthritis. Ann Intern Med. 1987;107:725-31.
5. Nadelman RB, Pavia CS, Magnarelli LA, Wormser GP. Isolation of Borrelia burgdorferi from the blood of seven patients with Lyme disease. Am J Med. 1990;88:21-6.
6. Steere AC, Grodzicki RL, Kornblatt AN, Craft JE, Barbour AG, Burgdorfer W, et al. The spirochetal etiology of Lyme disease. N Engl J Med. 1983;308:733-40.
7. Wormser GP, Nowakowski J, Nadelman RB, Bittker S, Cooper D, Pavia C. Improving the yield of blood cultures for patients with early Lyme disease. J Clin Microbiol. 1998;36:296-8.
8. Centers for Disease Control and Prevention. Case definitions for infectious conditions under public health surveillance: Lyme disease (revised 9/96). MMWR Morb Mortal Wkly Rep. 1997;46(RR-10):20-1.
9. Wormser GP, Nadelman RB, Dattwyler RJ, Dennis DT, Shapiro ED, Steere AC, et al. Practice guidelines for the treatment of Lyme disease. The Infectious Diseases Society of America. Clin Infect Dis. 2000;31 Suppl 1:1-14.
10. Luft BJ, Dattwyler RJ, Johnson RC, Luger SW, Bosler EM, Rahn DW, et al. Azithromycin compared with amoxicillin in the treatment of erythema migrans. A double-blind, randomized, controlled trial. Ann Intern Med. 1996;124:785-91.
11. Schwartz I, Wormser GP, Schwartz JJ, Cooper D, Weissensee P, Gazumyan A, et al. Diagnosis of early Lyme disease by polymerase chain reaction amplification and culture of skin biopsies from erythema migrans lesions. J Clin Microbiol. 1992;30:3082-8.
12. Wormser GP, Bittker S, Cooper D, Nowakowski J, Nadelman RB, Pavia C. Yield of large-volume blood cultures in patients with early Lyme disease. J Infect Dis. 2001;184:1070-2.
13. Liveris D, Varde S, Iyer R, Koenig S, Bittker S, Cooper D, et al. Genetic diversity of Borrelia burgdorferi in Lyme disease patients as determined by culture versus direct PCR with clinical specimens. J Clin Microbiol. 1999;37:565-9.
14. Aguero-Rosenfeld ME, Nowakowski J, Bittker S, Cooper D, Nadelman RB, Wormser GP. Evolution of the serologic response to Borrelia burgdorferi in treated patients with culture-confirmed erythema migrans. J Clin Microbiol. 1996;34:1-9.
15. Harrel FE Jr. Regression Modeling Strategies. New York: Springer-Verlag; 2001.
16. Piesman J, Schneider BS, Zeidner NS. Use of quantitative PCR to measure density of Borrelia burgdorferi in the midgut and salivary glands of feeding tick vectors. J Clin Microbiol. 2001;39:4145-8.
17. Bakken JS, Aguero-Rosenfeld ME, Tilden RL, Wormser GP, Horowitz HW, Raffalli JT, et al. Serial measurements of hematologic counts during the active phase of human granulocytic ehrlichiosis. Clin Infect Dis. 2001;32:862-70.
18. Kim N, Rosenbaum GS, Cunha BA. Relative bradycardia and lymphopenia in patients with babesiosis. Clin Infect Dis. 1998;26:1218-9.