Treatment of Staphylococcus epidermidis endophthalmitis with intravitreal moxifloxacin in a rabbit model

Tohoku Journal of Experimental Medicine

Volumn 205, Issue 3, 2005, Pages 223-229

  Ermis, Sitki Samet ^a,c   Cetinkaya, Zafer ^a   Kiyici, Halil ^b   Ozturk, Faruk ^a  

^a AFYON KOCATEPE UNIVERSITY   (Turkey)

^b BASKENT UNIVERSITY   (Turkey)

^c NONE   (Turkey)

Author keywords

Dexamethasone; Endophthalmitis; Moxifloxacin; Staphylococcus epidermidis

Indexed keywords

CORTICOSTEROID; DEXAMETHASONE; MOXIFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG EFFICACY; ENDOPHTHALMITIS; EYE INJURY; EYE SURGERY; MONOTHERAPY; NONHUMAN; POSTOPERATIVE INFECTION; RABBIT; STAPHYLOCOCCUS EPIDERMIDIS; STAPHYLOCOCCUS INFECTION;

ADRENAL CORTEX HORMONES; ANIMALS; ANTI-INFECTIVE AGENTS; AZA COMPOUNDS; DEXAMETHASONE; DISEASE MODELS, ANIMAL; ENDOPHTHALMITIS; EYE INFECTIONS, BACTERIAL; INFLAMMATION; QUINOLINES; RABBITS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS EPIDERMIDIS; STEM CELLS; TIME FACTORS; VITREOUS BODY;

EID: 17844374114     PISSN: 00408727     EISSN: None     Source Type: Journal    
DOI: 10.1620/tjem.205.223     Document Type: Article

References (33)

1. Aaberg, T.M., Jr., Flynn, H.W., Jr., Schiffman, J. & Newton, J. (1998) Nosocomial acute-onset postoperative endophthalmitis survey. A 10-year review of incidence and outcomes. Ophthalmology, 105, 1004-1010.
2. Aguilar, H.E., Meredith, T.A., Drews, C., Grossniklaus, H., Sawant, A.D. & Gardner, S. (1996) Comparative treatment of experimental Staphylococcus aureus endophthalmitis. Am. J. Ophthalmol., 121 310-317.
3. Baum, J., Peyman, G.A. & Barza, M. (1982) Intravitreal administration of antibiotic in the treatment of bacterial endophthalmitis. III. Consensus. Surv. Ophthalmol., 26, 204-206.
4. Callegan, M.C., Engelbert, M., Parke, D.W. II., Jett, B.D. & Gilmore, M.S. (2002) Bacterial endophthalmitis: epidemiology, therapeutics, and bacterium-host interactions. Clin. Microbiol. Rev. 15, 111-124.
5. Callegan, M.C., Booth, M.C., Jett, B.D. & Gilmore, M.S. (1999) Pathogenesis of gram-positive bacterial endophthalmitis. Infect. Immun., 67, 3348-3356.
6. Chen, J., Fujino, Y. & Takahashi, T. (1999) Experimental uveitis induced by intravitreal or intravenous lipoteichoic acid in rabbits. Jpn. J. Ophthalmol., 43, 368-374.
7. Driebe, W.T. Jr., Mandelbaum, S., Forster, R.K., Schwartz, L.K. & Culbertson, W.W. (1986) Pseudophakic endophthalmitis. Diagnosis and management. Ophthalmology. 93, 442-448.
8. Endophthalmitis Vitrectomy Study Group. (1995) Results of the Endophthalmitis Vitrectom Study. A randomized trial of immediate vitrectomy and of intravenous antibiotics for the treatment of postoperative bacterial endophthalmitis. Arch. Ophthalmol., 13 1479-1496.
9. Ferencz, J.R., Assia, E.I., Diamantstein, L. & Rubinstein, E. (1999) Vancomycin concentration in the vitreous after intravenous and intravitreal administration for postoperative endophthalmitis. Arch. Ophthalmol., 117, 1023-1027.
10. Forster, R.K. (1992) Experimental postoperative endophthalmitis. Trans. Am. Ophthalmol. Soc., 90, 505-559.
11. Foster, R.E., Martinez, J.A., Murray, T.G., Rubsamen, P.E., Flynn, H.W. Jr. & Forster, R.K. (1996) Useful visual outcomes after treatment of Bacillus cereus endophthalmitis. Ophthalmology, 103 390-397.
12. Garcia-Saenz, M.C., Arias-Puente, A., Fresnadillo-Martinez, M.J. & Carrasco-Font C. (2001) Human aqueous humor levels of oral ciprofloxacin, levofloxacin, and moxifloxacin. J. Cataract Refract. Surg., 27, 1969-1974.
13. Hassan, I.J. (1994) Endophthalmitis--problems, progress and prospects. J. Antimicrob. Chemother, 33, 383-386.
14. Jett, B.D., Jensen, H.G., Atkuri, R.V. & Gilmore, M.S. (1995) Evaluation of therapeutic measures for treating endophthalmitis caused by isogenic toxin-producing and toxin-nonproducing Enterococcus faecalis strains. Invest. Ophthalmol. Vis Sci., 36, 9-15.
15. Kowalski, R.P., Romanowski, E.G., Mah, F.S., Yates, K.A. & Gordon, Y.J. (2004) Topical prophylaxis with moxifloxacin prevents endophthalmitis in a rabbit model. Am. J. Ophthalmol., 138, 33-37.
16. Mather, R., Karenchak, L.M., Romanowski, E.G. & Kowalski, R.P. (2002) Fourth generation fluoroquinolones: new weapons in the arsenal of ophthalmic antibiotics. Am. J. Ophthalmol., 133, 463-466.
17. Maxwell, D.P. Jr., Brent, B.D., Orillac, R., Baber, W.B. & Mayeux, P.A. (1993) A natural history study of experimental Staphylococcus epidermidis endophthalmitis. Curr. Eye Res., 12 907-912.
18. Maxwell, D.P. Jr., Brent, B.D., Diamond, J.G. & Wu, L. (1991) Effect of intravitreal dexamethasone on ocular histopathology in a rabbit model of endophthalmitis. Ophthalmology, 98, 1370-1375.
19. Meredith, T.A., Aguilar, H.E., Drews, C., Sawant, A., Gardner, S., Wilson, L.A. & Grossniklaus, H.E. (1996) Intraocular dexamethasone produces a harmful effect on treatment of experimental Staphylococcus aureus endophthalmitis. Trans. Am. Ophthalmol. Soc., 94, 241-252.
20. Meredith, T.A., Aguilar, H.E., Miller, M.J., Gardner, S.K., Trabelsi, A. & Wilson, L.A. (1990a) Comparative treatment of experimental Staphylococcus epidermidis endophthalmitis. Arch. Ophthalmol., 108, 857-860.
21. Meredith, T.A., Trabelsi, A., Miller, M.J., Aguilar, E. & Wilson, L.A. (1990b) Spontaneous sterilization in experimental Staphylococcus epidermidis endophthalmitis. Invest. Ophthalmol. Vis. Sci., 31, 181-186.
22. Merino, G., Fujino, Y. & Hanashiro, R.K. (1998) Lipoteichoic acid as an inducer of acute uveitis in the rat. Invest. Ophthalmol. Vis. Sci., 39, 1251-1256.
23. Peyman, G.A., Vastine, D.W. & Raichand, M. (1978) Symposium: Postoperative endophthalmitis: Experimental aspects and their clinical application. Ophthalmology, 85, 374-385.
24. Pleyer, U., Mondino, B.J., Adamu, S.A., Pitchekian-Halabi, H., Engstrom, R.E. & Glasgow, B.J. (1992) Immune response to Staphylococcus epidermidis-induced endophthalmitis in a rabbit model. Invest. Ophthalmol. Vis. Sci., 33, 2650-2663.
25. Quie, P.G. & Belani, K.K. (1987) Coagulase-negative staphylococcal adherence and persistence. J. Infect. Dis., 156 543-547.
26. Ruiz, J. (2003) Mechanisms of resistance to quinolones: target alterations, decreased accumulation and DNA gyrase protection. J. Antimicrob. Chemother, 51, 1109-1117.
27. Scheld, W.M. (2003) Maintaining fluoroquinolone class efficacy: review of influencing factors. Emerg. Infect. Dis., 9 1-9.
28. Smith, A., Pennefather, P.M., Kaye, S.B. & Hart, C.A. (2001) Fluoroquinolones: place in ocular therapy. Drugs, 61, 747-761.
29. Smith, M.A., Sorenson, J.A., Lowy, F.D., Shakin, J.L., Harrison, W. & Jakobiec, F.A. (1986) Treatment of experimental methicillin-resistant Staphylococcus epidermidis endophthalmitis with intravitreal vancomycin. Ophthalmology, 93, 1328-1335.
30. Somani, S., Grinbaum, A. & Slomovic, A.R. (1997) Postoperative endophthalmitis: incidence, predisposing surgery, clinical course and outcome. Can. J. Ophthalmol., 32, 303-310.
31. Speaker, M.G., Milch, F.A., Shah, M.K., Eisner, W. & Kreiswirth, B.N. (1991) Role of external bacterial flora in the pathogenesis of acute postoperative endophthalmitis. Ophthalmology, 98, 639-649.
32. Yoshizumi, M.O., Lee, G.C., Equi, R.A., Kim, I.T., Pitchekian-Halabi, H., Adamu, S.A. & Mondino, B.J. (1998) Timing of dexamethasone treatment in experimental staphylococcus aureus endophthalmitis. Retina, 18, 130-135.
33. Vallar, R., Wilson, C.A. & Park, S.S. (1995) Effect of intravitreal dexamethasone on the blood-ocular barrier breakdown associated with pneumococcal endophthalmitis in rabbits. Invest. Ophthalmol. Vis. Sci., 36 (Suppl.), 790.