Loxoprofen inhibits facilitated micturition reflex induced by acetic acid urinary bladder infusion of the rats

Biomedical Research

Volumn 26, Issue 1, 2005, Pages 29-33

  Shinozaki, Sachiyo ^a   Saito, Motoaki ^b   Kawatani, Masahito ^a  

^a AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; LOXOPROFEN; PROSTAGLANDIN E2; NONSTEROID ANTIINFLAMMATORY AGENT; PHENYLPROPIONIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER CONTRACTION; CONTROLLED STUDY; CYSTITIS; CYSTOMETRY; DRUG EFFICACY; DRUG RESPONSE; MALE; MICTURITION REFLEX; NONHUMAN; RAT; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; ANIMAL; BLADDER; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; MICTURITION; MUSCLE CONTRACTION; PATHOPHYSIOLOGY; PHYSIOLOGY; REFLEX; SPRAGUE DAWLEY RAT;

ANIMALIA;

ACETIC ACID; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYSTITIS; DINOPROSTONE; MALE; MUSCLE CONTRACTION; PHENYLPROPIONATES; RATS; RATS, SPRAGUE-DAWLEY; REFLEX; URINARY BLADDER; URINATION;

EID: 17844371061     PISSN: 03886107     EISSN: 1880313X     Source Type: Journal    
DOI: 10.2220/biomedres.26.29     Document Type: Article

References (26)

1. Andersson KE and Hedlund P (2002) Pharmacologic perspective on the physiology of the lower urinary tract. Urology 60, 13-20
2. Araki T, Yokoyama T and Kumon H (2004) Effectiveness of a nonsteroidal anti-inflammatory drug for nocturia on patients with benign prostatic hyperplasia: a prospective non-randomized study of loxoprofen sodium 60 mg once daily before sleeping. Acta Med Okayama 56, 45-49.
3. Birder LA and de Groat WC (1992) Increased c-fos expression in spinal neurons after irritation of the lower urinary tract in the rat. J Neurosci 12, 4878-4889.
4. Brown WW, Zenser TV and Davis BB (1980) Prostaglandin E2 production by rabbit urinary bladder. Am J Physiol 239, F452-F458.
5. de Groat WC, Yoshiyama M, Ramage AG, Yamamoto T and Somogyi GT (1999) Modulation of voiding and storage reflexes by activation of alpha1-adrenoceptors. Eur Urol 36, 68-73.
6. de Groat WC, Booth AM and Yoshimura N (1993) Neurophysiology of micturition and modification in animal model of human disease. In: The Autonomic Nervous System, Vol 3 (Maggi CA, ed), pp227-290, Harwood Academic, London.
7. Habler HJ, Janig W and Koltzenburg M (1990) Activation of unmyelinated afferent fibres by mechanical stimuli and inflammation of the urinary bladder in the cat. J Physiol 425, 545-562.
8. Honma Y (2004) Epidemiology of overactive bladder. Auton Nerv Syst (Tokyo) 41, 313-315.
9. Hu VY, Malley S, Dattilio A, Folsom JB, Zvara P and Vizzard MA (2003) COX-2 and prostanoid expression in micturition pathways after eye cyclophosphamide-induced cystitis in the rat. Am J Physiol Regul Integr Comp Physiol 284, R574-R585.
10. Ishida F, Sato T, Imaizumi M, Funayama N, Ikegami K, Nimura T and Kawatani M (2003) MK-801 inhibits the micturition reflex in chronic bladder irritation caused by crystalluria in the rat. Auton Neurosci 105, 1-7.
11. Ishizuka O, Mattiasson A and Andersson KE (1995) Prostaglandin E2-induced bladder hyperactivity in normal, conscious rats: involvement of tachykinins? J Urol 153, 2034-2038.
12. Kawatani M, Ikeda M and Ishihama H (2004) Overactive bladder might increase the primary afferent nerve activity from the urinary bladder. Auton Nerv Syst 41, 316-319.
13. Lynes WL, Flynn SD, Shortliffe LD, Lemmers M, Zipser R, Roberts LJ 2nd and Stamey TA (1987) Mast cell involvement in interstitial cystitis. J Urol 138, 746-752.
14. Marsh FP (1976) The frequency-dysuria syndrome. In: Urology, Vol 2 (Blandy J, ed), pp 734-752, Blackwell, London.
15. Mitchell JA and Warner TD (1999) Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapy, Br J Pharmacol 128, 1121-1132.
16. Mikhailidis DP, Jeremy JY and Dandona P (1987) Urinary bladder prostanoids their synthesis, function and possible role in the pathogenesis and treatment of disease. J Urol 137, 577-582.
17. Morikawa K, Fukuoka M, Kakiuchi M, Kato H, Ito Y and Gomi Y (1990) Detrusor hyperreflexia induced by intravesical instillation of xylene in conscious rats. Jpn J Pharmacol 52,587-595.
18. Morrison J (1999) The activation of bladder wall afferent nerves. Exp Physiol 184, 131-136.
19. Palea S, Toson G, Pietra C, Trist DG, Artibani W, Romano O and Corsi M (1988) Pharmacological characterization of thromboxane prostanoid receptors in human isolated urinary bladder. Br J Pharmacol 124, 865-872.
20. Schroder A, Newgreen D and Andersson KE (2004) Detrusor responses to prostaglandin E2 and bladder outlet obstruction in wild-type and Ep1 receptor knockout mice. J Urol 172. 1166-1170.
21. Scolari F, Caridi G, Rampoldi L, Tardanico R, Izzi C, Pirulli D, Amoroso A, Casari G and Ghiggeri GM (2004) Uromodulin storage diseases: clinical aspects and mechanisms. Am J Kidney 44, 987-999.
22. Takagi-Matsumoto H, Ng B, Tsukimi Y and Tajimi M (2004) Effects of NSAIDs on bladder function in normal and cystitis rats: a comparison study of aspirin, indomethacin, and ketoprofen. J Pharmacol Sci 95, 458-465.
23. Tsukimi Y, Mizuyachi K, Matsumoto H, Sato M, Ng B and Tajimi M (2004) Mechanism of action by which alleviates detrusor hyperactivity in rats. J Pharmacol Sci 95, 101-107.
24. Wheeler MA, Yoon JH, Olsson LE and Weiss RM (2001) Cyclooxygenase-2 protein and prostaglandin E, production are up-regulated in a rat bladder inflammation model. Eur J Pharmacol 417, 239-248.
25. Yoshimura N (1999) Bladder afferent pathway and spinal cord injury: possible mechanisms inducing hyperreflexia of the urinary bladder. Prog Neurobiol 57, 583-606.
26. Yoshiyama M, Roppolo JR and de Groat WC (1994) Interactions between glutamatergic and monoaminergic systems controlling the micturition reflex in the urethane-anesthetized rat, Brain Res 639, 300-308.