Sesquiterpenoids from Pulicaria canariensis and their cytotoxic activities

Journal of Natural Products

Volumn 68, Issue 4, 2005, Pages 523-531

  Triana, Jorge ^a,b   López, Mariana ^a,b   Pérez, Francisco J ^a,b   González Platas, Javier ^c   Quintana, José ^a,b   Estévez, Francisco ^a,b   León, Francisco ^b,d   Bermejo, Jaime ^d  

^a UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

^b Madrid Spain   (Spain)

^c UNIVERSIDAD DE LA LAGUNA   (Spain)

^d INSTITUTO DE PRODUCTOS NATURALES Y AGROBIOLOGÍA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

5,7 DIHYDROXY 3,3',4' TRIMETHOXYFLAVONE; 6,15ALPHA EPOXY 1BETA,4BETA DIHYRDROXYEUSDESMANE; 7,4' DI O METHYLDIHYDROKAEMPFEROL; CALENDULADIOL; CASPASE 3; CASPASE 8; DIHYDROQUERCETIN 7,3' DIMETHYL ETHER; ERGOSTEROL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PULICANADIENAL A; PULICANADIENAL B; PULICANADIENOL; PULICANARAL A; PULICANARAL B; PULICANARAL C; PULICANDIENE A; PULICANDIENE B; PULICANDIENE C; PULICANOL; PULICANONE; PULIOPLOPANONE A; PULIOPLOPANONE B; SESQUITERPENE; SESQUITERPENOID; STIGMASTEROL; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ASTERACEAE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG ISOLATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HYDROLYSIS; LEUKEMIA CELL LINE; MICROSCOPY; MYELOID LEUKEMIA; PROTEIN DEGRADATION; PULICARIA CANARIENSIS; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; ASTERACEAE; CASPASES; DRUG SCREENING ASSAYS, ANTITUMOR; GALLIC ACID; GLUCOSE; HL-60 CELLS; HUMANS; PLANTS, MEDICINAL; POLY(ADP-RIBOSE) POLYMERASES; SESQUITERPENES; SPAIN; TUMOR CELLS, CULTURED;

EID: 17844370795     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np0496183     Document Type: Article

References (24)

1. Bramwell, D.; Bramwell, Z. I. Flores Silvestres de las Islas Canarias; Rueda S. L., Ed.; Madrid, 2001.
2. Grieve, M. A Modern Herbal; Penguin Books: Harmondsworth, UK, 1980; p 32.
3. Awadh, A. N. A.; Julich, W. D.; Kusnick, C.; Lindequist, U. J. Ethnopharmacol. 2001, 74, 173-179.
4. Mahfouz, M.; Ghazal, A.; El-Dakhakhny, M.; Ghoneim, M. T. J. Drug Res. 1973, 5, 151-172.
5. Williams, C. A.; Harborne, J. B.; Greenham, J. Biochem. Syst. Ecol. 2000, 28, 679-687.
6. Marco, J. A.; Sanz, J. F.; Albiach, R. Phytochemistry 1992, 31, 2409-2413.
7. Dendougui, H.; Benayache, S.; Benayache, F.; Connolly, J. D. Fitoterapia 2000, 71, 373-378.
8. Eshbakova, K. A.; Saidkhodzhaev, A. I. Chem. Nat. Prod. 2001, 37, 196-197.
9. Triana, J.; Lopez, M.; Rico, M.; González-Platas, J.; Quintana, J.; Estevez, F.; León, F.; Bermejo, J. J. Nat. Prod. 2003, 66, 943-948.
10. Rivero, A.; Quintana, J.; Eiroa, J. L.; Lopez, M.; Triana, J.; Bermejo, J.; Estévez, F. Eur. J. Pharmacol. 2003, 482, 77-84.
11. Shoppee, C. W. Chemistry of the Sterols; Butterworth: London, 1964; pp 62-63.
12. González, A. G.; Bermejo, J. B.; Rodríguez, P. E. M.; Hernández, H. C. Planta Med. 1992, 55, 214-218.
13. Datanarayana, A. P.; Kumar, N. S.; Sultanbawa, M. U.; Balasubramaniam, S. J. Chem. Soc., Perkin Trans, 1 1981, 2717-2723.
14. Islam, M. T.; Tahara, S. Phytochemistry 2000, 54, 901-907.
15. González, A. G.; Bermejo, J.; Triana, J.; Eiroa, J. L.; Lopez, M. J. Nat. Prod. 1995, 58, 432-437.
16. Balza, F.; Towers, G. H. N. Phytochemistry 1984, 23, 2333-2337.
17. Fang, N.; Yu, S.; Mabry, T. J.; Abboud, K. A.; Simonsen, S. H. Phytochemistry 1988, 27, 3187-3196.
18. Barrero, A. F.; Herrador, M. M.; Quilez, J. F.; Alvarez-Manzaneda, R.; Portal, D.; Gavin, J. A.; Gravalos, D. G.; Simmonds, M. S. J.; Blaney, W. M. Phytochemistry 1999, 529-541.
19. Pascual J. T.; Moran, J. R.; Hernández, J. M.; Grande, M. Phytochemistry 1985, 24, 1779-1783.
20. Wong, H. F.; Brown, G. D. Phytochemistry 2002, 59, 529-536.
21. Ohtani, I.; Kusumi, T.; Kashman, Y.; Kakisawa, H. J. Am. Chem. Soc. 1991, 113, 4092-4096.
22. Joseph-Nathan, P.; Villagomez, J. R.; Roman, L. U.; Hernandez, J. D. Phytochemistry 1990, 29, 977-979.
23. Tamayo-Castillo, G.; Jakupovic, J.; Bohlmann, F.; Rojas, A.; Castro, V.; King, R. M. Phytochemistry 1988, 27, 2893-2897.
24. Benyahia, S.; Benayache, S.; Benayache, F.; Quintana, J.; López, M.; León, F.; Hernández, J. C.; Estévez, F.; Bermejo, J. J. Nat. Prod. 2004, 67, 527-531.