Bioactive sesquiterpenes from Santolina rosmarinifolia subsp. Canescens. A conformational analysis of the germacrane ring

Phytochemistry

Volumn 51, Issue 4, 1999, Pages 529-541

  Barrero, Alejandro F ^a   Herrador, M Mar ^a   Quilez, Jose F ^b   Alvarez Manzaneda, Ramon ^b   Portal, Dolores ^a   Gavin, Jose A ^c   Gravalos, Dolores G ^d   Simmonds, M S J ^e   Blaney, W M ^f  

^a Instituto de Biotecnologia   (Spain)

^b UNIVERSITY OF ALMERÍA   (Spain)

^c UNIVERSIDAD DE LA LAGUNA   (Spain)

^d PHARMAMAR S A   (Spain)

^e JODRELL LABORATORY   (United Kingdom)

^f UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Antifeedants; Biological activities; Compositae; Conformational study; Santolina rosmarinifolia subsp. canescens; Sesquiterpenes

Indexed keywords

ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; ASTERACEAE; HEXANE; SESQUITERPENE;

ANIMAL; ANTIMICROBIAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG SCREENING; GAS CHROMATOGRAPHY; HUMAN; INFRARED SPECTROSCOPY; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; MICROBIOLOGICAL EXAMINATION; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PLANT; PROTON NUCLEAR MAGNETIC RESONANCE;

ANIMALS; ANTI-INFECTIVE AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ASTERACEAE; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; SESQUITERPENES; TUMOR CELLS, CULTURED;

ANIMALIA; ASTERACEAE; SANTOLINA ROSMARINIFOLIA;

EID: 0033152555     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9422(99)00047-3     Document Type: Article

References (29)

1. Allinger N.L. J. Am. Chem. Soc. 99:1977;8127.
2. Allinger N.L., Sprague J.T. J. Am. Chem. Soc. 95:1973;3893.
3. Appendino, G. & Tettamazi, P., J. Chem. Soc. Perkin Trans. I, 1990, 2139.
4. Barrero A.F., Alvarez-Manzaneda E.J., Alvarez-Manzaneda R. Phytochemistry. 29:1990;3213.
5. Barrero A.F., Alvarez-Manzaneda R., Quílez J.F., Herrador M.M. Phytochemistry. 48:1998;807.
6. Barrero A.F., Herrador M.M., Molina Molina J., Quílez J.F., Quiros M. J. Nat. Prod. 57:1994;873.
7. Barrero A.F., Molina J., Oltra E., Altarejos J., Barragán A., Lara A., Segura M. Tetrahedron. 51:1995;3813.
8. Barrero A.F., Sánchez J.F., Arana E. Phytochemistry. 27:1988;3969.
9. Bergeron R.T., Davanangh P.F. Jr., Kline S.J., Porter C.W. Biochem. Biophys. Commun. 121:1984;848.
10. Bohlmann F., Zdero C. Chem. Ber. 101:1968;2062.
11. Bohlmann F., Jakupovic J., Ahmed M., Schuster A. Phytochemistry. 22:1983;1623.
12. Burket U., Allinger N.L. Molecular Mechanics. 1982;American Chemical Society, Washington, DC.
13. De Pascual Teresa J., González M.S., De Dios M.A., San Segundo J.M., Vicente S., Bellido I.S. Riv. Ital. E.P.P.O.S. 62:1981;355.
14. Evans F.E., Miller D.W., Cairns T., Baddeley G.V., Wenkert E. Phytochemistry. 21:1982;937.
15. Hall S.S., McEnroe F.J., Shue H.-J. J. Org. Chem. 40:1975;3306.
16. Imai K., Osawa E. Tetrahedron Lett. 30:1989;4251.
17. Imai K., Osawa E. QCPE Bull. 10:1990;38. Program No. 591.
18. Kitagawa I., Ciu Z., Son B.W., Kobayashi M., Kyogoku Y. Chem. Pharm. Bull. 35:1987;124.
19. Krebs H.C., Rakotoarimanga J.V., Habermehl G.G. Mag. Res. Chem. 28:1990;124.
20. Maqua M.P., Vines A.C.G., Caballero E., Grande M.C., Medarde M., Bellido I.S. Phytochemistry. 27:1988;3664.
21. Metwally M.A., Dawidar A. Die Pharmazie. 41:1986;522.
22. Milon A., Nakatani Y., Kintzinger J.-P., Ourisson F. Helv. Chim. Acta. 72:1989;1.
23. Pyrek J., Baranowska E. Tetrahedron Lett. 13:1973;809.
24. Sanz J.F., Garcia-Sarrión A., Marco J.A. Phytochemistry. 30:1991;3339.
25. Serena Sofware Programm, P.O. Box 3076, Bloomington, IN, 47402-3076.
26. Stahl-Biskup E., Laakso I. Planta Med. 56:1990;464.
27. Ugliengo P., Appendino G., Chiari G., Viterbo D. J. Mol. Struct. 222:1990;437.
28. Wada K., Enomoto Y., Munakata K. Agr. Biol. Chem. 34:1970;946.
29. Wenkert E., Baddeley G.V., Burfitt I.R., Moreno L.N. Org. Magn. Reson. 11:1978;337.