[3H]BQ-123 binding to native endothelin ETA receptors in human astrocytoma 1321N1 cells and screening of potential ligands

Pharmacology

Volumn 74, Issue 1, 2005, Pages 51-56

  Griessmeier, Kerstin J ^a   Müller, Christa E ^a,b  

^a UNIVERSITY OF BONN   (Germany)

^b Pharmazeutisches Institut   (Germany)

Author keywords

Astrocytoma cells; BQ 123; ETA receptor; Imidazo 1,2 c pyrimidines; Pyrimido 1,6 a pyrimidines; Radioligand binding

Indexed keywords

BQ 610; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR AGONIST; ENDOTHELIN A RECEPTOR ANTAGONIST; N ACETYLENDOTHELIN 1 [6-21][11,15 ALANINE]; PYRIMIDINE DERIVATIVE; RADIOLIGAND; TRITIUM; CYCLO(TRP ASP PRO VAL LEU); CYCLO(TRP-ASP-PRO-VAL-LEU); CYCLOPEPTIDE; LIGAND;

ARTICLE; ASTROCYTOMA CELL; BINDING ASSAY; CELL LINE; CELL MEMBRANE; CONTROLLED STUDY; DRUG COMPETITION; DRUG DETERMINATION; DRUG INHIBITION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SELECTIVITY; DRUG SPECIFICITY; HUMAN; HUMAN CELL; ISOTOPE LABELING; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RECEPTOR AFFINITY; SUBSTITUTION REACTION; ASTROCYTOMA; BINDING COMPETITION; IN VITRO STUDY; METABOLISM; PROTEIN BINDING; RADIOASSAY; TUMOR CELL LINE;

ASTROCYTOMA; BINDING, COMPETITIVE; CELL LINE, TUMOR; HUMANS; LIGANDS; PEPTIDES, CYCLIC; PROTEIN BINDING; PYRIMIDINES; RADIOLIGAND ASSAY; RECEPTOR, ENDOTHELIN A; TRITIUM;

EID: 17844368138     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000083983     Document Type: Article

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