Reversal of P-glycoprotein mediated multidrug resistance by a newly synthesized 1,4-benzothiazipine derivative, JTV-519

Cancer Letters

Volumn 187, Issue 1-2, 2002, Pages 111-119

  Che, Xiao Fang ^a   Nakajima, Yuichi ^a   Sumizawa, Tomoyuki ^a   Ikeda, Ryuji ^a   Ren, Xiao Qin ^a   Zheng, Chun Lei ^a   Mukai, Motoi ^a   Furukawa, Tatsuhiko ^a   Haraguchi, Misako ^a   Gao, Hui ^a   Sugimoto, Yoshikazu ^b   Akiyama, Shin ichi ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b CANCER CHEMOTHERAPY CENTER   (Japan)

Author keywords

JTV 519; Multidrug resistance; Multidrug resistance protein 1; P glycoprotein

Indexed keywords

4 [3 (4 BENZYL 1 PIPERIDINYL)PROPIONYL] 2,3,4,5 TETRAHYDRO 7 METHOXY 1,4 BENZOTHIAZEPINE; ANTINEOPLASTIC AGENT; AZIDOPHENYL AGOSTEROL A I 125; AZIDOPINE; BENZOTHIAZEPINE DERIVATIVE; DACTINOMYCIN; DOXORUBICIN; ETOPOSIDE; GLYCOPROTEIN P; IODINE DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; UNCLASSIFIED DRUG; VINCRISTINE;

ANIMAL CELL; ARTICLE; CELL STRAIN; CONTROLLED STUDY; DRUG INHIBITION; DRUG SYNTHESIS; DRUG TRANSPORT; EFFUSION; HUMAN; HUMAN CELL; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; REVERSAL REACTION;

ANTINEOPLASTIC AGENTS; CELL MEMBRANE; CELL SURVIVAL; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; PIPERAZINES; PYRIMIDINES; THIAZEPINES; TUMOR CELLS, CULTURED;

EID: 17744421180     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(02)00359-2     Document Type: Article

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