Ex Vivo Anthelmintic Activity of Albendazole-Sulphoxide Enantiomers

Journal of Parasitology

Volumn 90, Issue 2, 2004, Pages 407-409

  Bolas Fernandez F ^a   Rama Iniguez S ^a   Torrado, J J ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALBENDAZOLE SULFOXIDE; ANTHELMINTIC AGENT;

PARASITOLOGY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFICACY; DRUG MECHANISM; ENANTIOMER; EX VIVO STUDY; EXPERIMENTAL MODEL; LARVA; MOUSE; NEMATODIASIS; NONHUMAN; PARASITE ISOLATION; PARASITE VIRULENCE; TRICHINELLA SPIRALIS;

ALBENDAZOLE; ANIMALS; ANTHELMINTICS; DISEASE MODELS, ANIMAL; LARVA; MALE; MICE; PARASITIC SENSITIVITY TESTS; STEREOISOMERISM; TRICHINELLA SPIRALIS; TRICHINOSIS;

ANIMALIA; MURINAE; NEMATODA; TRICHINELLA SPIRALIS;

EID: 17744403314     PISSN: 00223395     EISSN: None     Source Type: Journal    
DOI: 10.1645/GE-3212RN     Document Type: Article

References (25)

1. ALVAREZ, L. I., F. A. IMPERIALE, S. F. SANCHEZ, G. A. MURNO, AND C. E. LANUSSE. 2000. Uptake of albendazole and albendazole sulphoxide by Haemaonchus contortus and Fasciola hepatica in sheep. Veterinary Parasitology 94: 75-89.
2. -, M. L. MOTTIER, S. F. SANCHEZ, AND C. E. LANUSSE. 2001. Ex vivo diffusion of albendazole and its sulphoxide metabolite into Ascaris suum and Fasciola hepatica. Parasitology Research 87: 929-934.
3. BOLAS-FERNANDEZ, F. 2002. Total anaerobiosis during in vitro culture in conventional cell culture media is required for retaining infectivity of Trichinella spiralis L1 larvae, Journal of Parasitology 88: 794-796.
4. CAPECE, B., G. CASTELLS, F. PEREZ, M. ARBOIX, AND C. CRISTOFOL. 2000. Pharmacokinetic behaviour of albendazole sulphoxide enantiomers in male and female sheep. Veterinay Research Communications 24: 339-348.
5. DELATOUR, P., E. BENOIT, S. BESSE, AND A. BOUKRA. 1991. Comparative enantioselectivity sulphoxidation of albendazole in man, dog and rats. Xenobiotica 21: 217-221.
6. -, -, F. GARNIER, AND S. BESSE. 1990. Chirality of the sulphoxide metabolites of fenbendazole and albendazole in sheep. Journal of Veterinary Pharmacology and Therapeutics 13: 361-366.
7. -, F. GARNIER, E. BENOIT, AND I. CAUDE. 1991. Chiral behaviour of the metabolite albendazole sulphoxide in sheep, goats and cattle. Research in Veterinary Sciences 50: 134-138.
8. FETTERER, R., R. S. REW, AND R. KNIGHT. 1982. Comparative efficacy of albendazole against Fasciola hepatica in sheep and calves: Relationship to serum drug metabolite levels. Veterinary Parasitology 11: 309-316.
9. GARCÍA, J. J., F. BOLAS, AND J. J. TORRADO. 1999. Quantitative determination of albendazole and its main matabolites in plasma. Journal of Chromatography B 723: 265-271.
10. -, -, AND -. 2003. Bioavailability and efficacy characteristics of two different oral liquid formulations of albendazole. International Journal of Pharmaceutics 250: 351-358.
11. HENNESSY, D., D. ALI, AND S. TREMAIN. 1994. The partition and fate of soluble and digest particulate associated oxfendazole and its metabolites in the gastrointestinal tract of sheep. International Journal for Parasitology 24: 327-333.
12. HORTON, J. 2000. Albendazole: A review of anthelmintic efficacy and safety. Parasitology 121: S113-S132.
13. LACEY, E. 1988. The role of the cytoskeletal protein, tubulin, in the mode of action and mechanism of drug resistance to benzimidazoles. International Journal for Parasitology 18: 885-936.
14. LANUSSE, C., L. GASCON, AND R. PRICHARD. 1995. Comparative plasma disposition kinetics of albendazole, fenbendazole, oxfendazole and their metabolites in adult sheep. Journal of Veterinary Pharmacology and Therapeutics 18: 196-203.
15. -, B. NARE, AND R. PRICHARD. 1993. Comparative sulphoxidation of albendazole by sheep and cattle liver microsomes. Xenobiotica 23: 285-295.
16. MARQUES, M. P., O. M. TAKAYANAGUI, P. S. BONATO, S. SANTOS, AND V. L. LANCHOTE. 1999. Enatioselective kinetic disposition of albendazole sulphoxide in patients with neurocysticercosis. Chirality 11: 218-223.
17. MARRINER, S., AND J. BOGAN. 1980. Pharmacokinetics of albendazole in sheep. American Journal of Veterinary Research 41: 1126-1129.
18. PROCHANZKOVA, A., M. CHOUKI, R. THEURILLAT, AND W. THORMANN. 2000. Therapeutic drug monitoring of albendazole: Determination of albendazole, albendazole sulphoxide and albendazole sulphone in human plasma using non aqueous capillary electrophoresis. Electrophoresis 21: 729-736.
19. RUEDA-POLO, S., J. J. TORRADO, F. BOLAS, AND S. TORRADO. 1998. A selective and simple RP-HPLC assay to quantify albendazole metabolites in plasma. Journal of Liquid Chromatography and Related Technologies 21: 2327-2340.
20. SANCHEZ, S., L. ALVAREZ, AND C. LANUSSE. 1997. Fasting induced changes on the pharmacokinetic behaviour of albendazole and its metabolites in cattle. Journal of Veterinay Pharmacology and Therapeutics 20: 38-47.
21. SOLANA, H., J. A. RODRIGUEZ, AND C. E. LANUSSE. 2001. Comparative metabolism of albendazole and albendazole sulphoxide by different helminth parasites. Parasitology Research 4: 275-280.
22. -, J. SALLOVITZ, R. NAJLE, J. A. RODRIGUEZ, AND C. E. LANUSSE. 2000. Liver sulphoxidation metabolism of albendazole in rat: Enantioselectivity and effect of methimazole. Methods and Findings in Experimental and Clinical Pharmacology 22: 83-88.
23. -, J. M. SALLOVITZ, C. E. LANUSSE, AND J. A. RODRÍGUEZ. 2002. Enantioselective binding of albendazole sulphoxide to cytosol proteins from helminth parasites. Methods and Findings in Experimental and Clinical Pharmacology 24: 7-13.
24. SOUHAILI-EL AMRI, H., X. FARGETTON, P. DELATOUR, AND A. BATT. 1987. Sulphoxidation of albendazole by the FAD-containing and cytochorme P-450 dependent mono-oxygenases from pig liver microsomes. Xenobiotica 17: 1159-1168.
25. VIRKEL, G., A. LIFSCHITZ, A. PIS, AND C. LANUSSE. 2002. In vitro ruminal biotransformation of benzimidazole sulphoxide anthelmintics: Enantioselective sulphoxidation in sheep and cattle. Journal of Veterinary Pharmacology and Therapeutics 25: 15-23.