Hypoglycemia activates compensatory mechanism of glucose metabolism of brain

Acta Biologica Hungarica

Volumn 52, Issue 1, 2001, Pages 35-45

  Márián, Teréz ^a   Balkay, L ^a   Fekete, I ^a   Lengyel, Zs ^a   Veress, G ^a   Esik O ^a   Tron L ^a   Krasznai, Z ^b  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b NATIONAL INSTITUTE OF ONCOLOGY   (Hungary)

Author keywords

CGMR; Dynamic FDG PET; Hypoglycemia

Indexed keywords

FLUORODEOXYGLUCOSE F 18; GLUCOSE; RADIOPHARMACEUTICAL AGENT;

ANIMAL; ANIMAL MODEL; ARTICLE; BRAIN; COMPUTER ASSISTED EMISSION TOMOGRAPHY; GLUCOSE BLOOD LEVEL; HYPOGLYCEMIA; METABOLISM; PHYSIOLOGY; RABBIT;

ANIMALS; BLOOD GLUCOSE; BRAIN; FLUORODEOXYGLUCOSE F18; GLUCOSE; HYPOGLYCEMIA; MODELS, ANIMAL; RABBITS; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 17744371125     PISSN: 02365383     EISSN: None     Source Type: Journal    
DOI: 10.1556/ABiol.52.2001.1.5     Document Type: Article

References (29)

1. Aller, B. C., Ehmann, S., Gilman-Sachs, A., Snyder, K. A. (1997) Flow cytometric analysis of glucose transport by rat brain cells. Cytometry 27, 262-268.
2. Dienel, G. A., Cruz, N. F., Mori, K., Holden, J., Sokoloff, L. (1991) Direct measurements of the γ of the lumped constant of the deoxyglucose method in rat brain: determination of γ and lumped constant from tissue glucose concentration or equilibrium tissue: plasma distribution ratio for methylglucose. J. Cereb. Blood Flow Metab. 11, 25-34.
3. Eng, H. L., DeLapaz, R. L., Frankel, K. A., Poljak, A., Phillips, M. H., Brennan, K. M, Woodruff, K. H., Valk, P. E., Steinberg, G. K., Fabrikant, J. I. (1991) MRI and PET delayed heavy-ion radiation injury in the rabbit brain. J. Radiation Oncology Biol. Phys. 20, 689-696.
4. Gamelli, R. L., Liu, H., He, L. K., Hoffmann, C. A. (1994) Alterations of glucose transporter mRNA and protein levels in brain following thermal injury and sepsis in mice. Shock 1, 395-400.
5. Germinario, R. J., Michaelidou, A. (1986) Hexose transport after glucose refeeding of glucose-starved human fibroblasts: 1. The effects of tunicamycin and cycloheximide. 2. Insulin binding and action. Biochem Biophys Res. Commun 140, 844-849.
6. 18F)-Fluoro-2-Deoxy-D-Glucose using aminopolyether supported nucleophilic substitution. J. Nucl. Med. 27, 235-238.
7. Hegedus, K., Keresztes, T., Fekete, I., Molnár, L. (1997) Effect of i.v. dipyridamol on cerebral blood flow, blood pressure, plasma adenosine and cAMP levels in rabbits. J. Neuro. Sci. 148, 153-157.
8. Hoh, C. K., Dahlbom, M., Hawkins, R. A., Glaspy, J. A., Yao, W. J., Lee, S. J., Maddahi, J., Phelps, M. E. (1994) Basic principles of positron emission tomography in oncology: quantification and whole body techniques. Wien Klin. Wochenschr. 106, 496-504.
9. Ishizu, K., Nishizawa, S., Yonekura, Y., Sadato, N., Magata, Y., Tamaki, N., Tsuchida, T., Okazawa, H., Miyatake, S., Ishikawa, M., Kikuchi, H., Konishi, J. (1994) Effects of hyperglycemia on FDG uptake in human brain and glioma. J. Nucl. Med. 35, 1104-1109.
10. 11C]KF17837. Ann. Nucl. Med. 3, 219-225.
11. Knuuti, J., Nuutila, P., Ruotsalainen, U., Saraste, M., Harkonen, R., Ahonen, A., Teras, M., Haaparanta, M., Wegelius, U., Haapanen, A. (1992) Euglicemic hyperinsulinemic clamp and oral glucose load in stimulating myocardial glucose utilization during positron emission tomography J. Nucl. Med. 33, 1255-1262.
12. Kubota, K., Kubota, R., Yamada, S., Tada, M., Takahashi, T., Iwata, R. (1996) Re-evalution of myocardial FDG uptake in hyperglycemia. J. Nucl. Med. 37, 1713-1717.
13. Lemmon, S. K., Sens, D. A., Buse, M. G. (1985) Insulin stimulation of glucose transport and metabolism in a human Wilms' tumor-derived myoblast-like cell line: modulation of hormone effects by glucose deprivation. J. Cell Physiol. 125, 456-464.
14. Lindholm, P., Minn, H., Leskinen-Kallio, S., Bergman, J., Ruotsalainen, U., Joensuu, H. (1993) Influence of the blood glucose concentration on FDG uptake in cancer-A PET study. J. Nucl. Med. 34, 1-6.
15. Maher, F., Vannucci, S. J., Simpson, I. A. (1994) Glucose transporter proteins in brain. FASEB J. 8, 1003-1011.
16. Nishioka, T., Oda, Y., Seino, Y., Yamamoto, T., Inagaki, N., Yano, H., Imura, H., Shigemoto, R., Kikuchi, H. (1992) Distribution of the glucose transporters in human brain tumors. Cancer Research 52, 3972-3979.
17. Pelligrini, D. A., LaManna, J. C., Duckrow, R. B., Bryan, R. M. Jr., Harik, S. I. (1992) Hyperglycemia and blood-brain barrier glucose transport. J. Cerebr. Blood Flow Metab. 12, 887-899.
18. Phelps, M. E., Huang, S. C., Hoffman, E. J., Selin, C., Sokoloff, L., Kuhl, D. E. (1979) Tomographic measurement of local cerebral glucose metabolic rate in humans with 2-[F-18]fluoro-2-deoxy-D-glucose: validation of Method. Ann. Neurol. 6, 371-388.
19. Sadiq, F., Holtzclaw, L., Chundu, K., Muzzafar, A., Devaskar, S. (1990) The ontogeny of the rabbit brain glucose transporter. Endocrinology 126, 2417-2424.
20. Shawver, L. K., Olson, S. A., White, M. K., Weber, M. J. (1987) Degradation and biosynthesis of the glucose transporter protein in chicken embryo fibroblasts transformed by the src oncogene. Mol. Cell Biol. 7, 2112-2118.
21. Sieber, J. E., Traystman, R. J. (1992) Special issues: Glucose and the brain. Critical Care Med. 20, 104-114.
22. 14C]deoxiglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J. Neurochem. 28, 897-916.
23. Suda, S., Shinohara, M., Miyaoka, M., Lucignani, G., Kennedy, C., Sokoloff, L. (1990) The lumped constant of the deoxyglucose method in hypoglycemia: effects of moderate hypoglycemia on local cerebral glucose utilization in the rat. J. Cereb. Blood Flow Metab. 10, 499-509.
24. Torizuka, T., Clavo, A. C., Wahl, R. L. (1997) Effect of hyperglycemia on in vitro tumor uptake of tritiated FDG, thymidine, L-methionine and L-leucine, J. Nucl. Med. 38, 382-386.
25. Urabe, T., Hattori, N., Nagamatsu, S., Sawa, H., Mizuno, Y. (1996) Expression of glucose transporters in rat brain following transient focal ishemic injure. J Neurochem. 67, 265-271.
26. Vannucci, S. J., Seaman, L. B., Vannucci, R. C. (1996) Effect of hypoxia-ischemia on GLUT1 and GLUT3 glucose transporters in immature rat brain. J. Cereb. Blood Flow Metab. 16, 77-81.
27. 18F]fluoro-2-deoxy-D-glucose in rodents with mammary carcinoma. Radiology 183, 643-647.
28. Wahl, L. R. (1996) Targeting glucose transporters for tumor imaging: "Sweet" idea, "Sour" result. J. Nucl. Med. 37, 1038-104.
29. Walker, P. S., Donovans, J. A., Van Ness, B. G., Fellows, R. E., Pessin, J. E. (1988) Glucose-dependent regulation of the glucose transport activity, protein and mRNA in primary cultures of rat brain glial cells. J. Biol. Chem. 263, 15594-15601.