Sonogashira cross-coupling in the synthesis of acyclic nucleoside phosphonates: Preparation of 6-[(phosphonomethoxy)alkynyl]- and 6-[(phosphonomethoxy)alkyl]pyrimidines

Collection of Czechoslovak Chemical Communications

Volumn 70, Issue 2, 2005, Pages 247-258

  Hocková, Dana ^a   Masojídková, Milena ^a   Holý, Antonín ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

Acyclic nucleoside phosphonates; Alkynes; Antivirals; Cross coupling reactions; Hydrogenation; Nucleosides; Nucleotide analogues; Pyrimidines; Sonogashira reaction

Indexed keywords

2 AMINO 4 CHLORO 6 [3 [(DIISOPROPOXYPHOSPHORYL)METHOXY]PROP 1 YN 1 YL]PYRIMIDINE; 2 AMINO 4 CHLORO 6 BIS[3 [(DIISOPROPOXYPHOSPHORYL)METHOXY]PROP 1 YN 1 YL]PYRIMIDINE; 2 AMINO 4 HYDROXY 6 [3 (PHOSPHOMETHOXY)PROP 1 YN 1 YL]PYRIMIDINE; 2 AMINO 4 HYDROXY 6 [3 (PHOSPHOMETHOXY)PROPYL]PYRIMIDINE; 2 AMINO 4 HYDROXY 6 [3 [(DIISOPROPOXYPHOSPHORYL)METHOXY]PROP 1 YN 1 YL]PYRIMIDINE; 2 AMINO 4,6 BIS(3 HYDROXYPROPYL)PYRIMIDINE; 2,4 DIAMINO 6 (3 HYDROXYPROPYL)PYRIMIDINE; 2,4 DIAMINO 6 (4 HYDROXYBUTYL)PYRIMIDINE; 2,4 DIAMINO 6 [3 (PHOSPHOMETHOXY)BUTYL]PYRIMIDINE; 2,4 DIAMINO 6 [3 (PHOSPHOMETHOXY)PROP 1 YN 1 YL]PYRIMIDINE; 2,4 DIAMINO 6 [3 (PHOSPHOMETHOXY)PROPYL]PYRIMIDINE; 2,4 DIAMINO 6 [3 [(DIISOPROPOXYPHOSPHORYL)METHOXY]PROP 1 EN 1 YL]PYRIMIDINE; 2,4 DIAMINO 6 [3 [(DIISOPROPOXYPHOSPHORYL)METHOXY]PROP 1 YN 1 YL]PYRIMIDINE; 2,4 DIAMINO 6 [3 [(DIISOPROPOXYPHOSPHORYL)METHOXY]PROPYL]PYRIMIDINE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CHEMICAL BOND; DRUG SYNTHESIS; SONOGASHIRA REACTION;

EID: 17744366648     PISSN: 00100765     EISSN: None     Source Type: Journal    
DOI: 10.1135/cccc20050247     Document Type: Article

References (16)

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