Virulence and mutation rates of Salmonella typhimurium strains with increased mutagenic strength in a mouse model

FEMS Microbiology Letters

Volumn 187, Issue 2, 2000, Pages 145-150

  Campoy, Susana ^a   Pérez De Rozas, Ana M ^b   Barbé, Jordi ^a   Badiola, Ignacio ^b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b IRTA   (Spain)

Author keywords

mutS gene; Salmonella typhimurium; SOS mutagenesis; Virulence

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BACTERIAL VIRULENCE; DNA REPAIR; ESCHERICHIA COLI; FEMALE; LD 50; MOUSE; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; STRAIN DIFFERENCE;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BACTERIAL PROTEINS; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI PROTEINS; FEMALE; MICE; MICE, INBRED BALB C; MUTATION; MUTS DNA MISMATCH-BINDING PROTEIN; SALMONELLA INFECTIONS, ANIMAL; SALMONELLA TYPHIMURIUM; SOS RESPONSE (GENETICS); VIRULENCE;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 17644439875     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(00)00192-0     Document Type: Article

References (21)

1. Arber W. Genetic variation: molecular mechanisms and impact on microbial evolution. FEMS Microbiol. Rev. 24:2000;1-7.
2. Gilsdorf J.R. Antigenic diversity and gene polymorphism in Haemophilus influenzae. Infect. Immun. 66:1998;5053-5059.
3. LeClerc j.E., Li B., Payne W.L., Cebula T.A. High mutation frequencies among Escherichia coli and Salmonella pathogens. Science. 274:1996;1208-1211.
4. Matic I., Radman M., Taddei F., Picard B., Doit C., Bingen E., Denamur E., Elion J. Highly variable mutation rates in commensal and pathogenic Escherichia coli. Science. 277:1997;1833-1834.
5. Horst J.P., Wu T., Marinus M.G. Escherichia coli mutator genes. Trends Microbiol. 7:1999;29-36.
6. Walker G.C. Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli. Microbiol. Rev. 48:1984;60-93.
7. 2C is an error-prone DNA polymerase, Escherichia coli pol V. Proc. Natl. Acad. Sci. USA. 96:1999;8919-8924.
8. Runyen-Janecky L.J., Hong M., Payne S.M. The virulence plasmid-encoded impCAB operon enhances survival and induced mutagenesis in Shigella flexneri after exposure to UV radiation. Infect. Immun. 67:1999;1415-1423.
9. Koch H.W., Cebula T.A., Foster P.L., Eisenstadt E. UV mutagenesis in Salmonella typhimurium is umuDC dependent despite the presence of samAB. J. Bacteriol. 174:1992;2809-2815.
10. Koch W.H., Kopsidas G., Meffle B., Levine A.S., Woodgate R. Analysis of chimeric UmuC proteins: identification of regions in Salmonella typhimurium UmuC important for mutagenic activity. Mol. Gen. Genet. 23:1996;121-129.
11. Jordan A., Aragall E., Gibert I., Barbé J. Promoter identification and expression analysis of Salmonella typhimurium and Escherichia coli nrdEF operons encoding one of two class I ribonucleotide reductases present in both bacteria. Mol. Microbiol. 19:1996;777-790.
12. Clerch B., Bravo J.M., Llagostera M. Efficiency of MucAB and Escherichia coli UmuDC proteins in quinolone and UV mutagenesis in Salmonella typhimurium: effect of MucA and UmuD processing. Mutat. Res. 349:1996;201-208.
13. Reed L.J., Muench H. A simple method for estimating fifty percent endpoints. Am. J. Hyg. 27:1938;493-497.
14. Kahn S., Everest P., Servos S., Foxwell N., Zähringer U., Brade H., Rietschel E.T., Dougan G., Charles I.G., Maskell D.J. A lethal role for lipid A in Salmonella infections. Mol. Microbiol. 29:1998;571-579.
15. Björkman J., Hughes D., Andersson D.I. Virulence of antibiotic-resistant Salmonella typhimurium. Proc. Natl. Acad. Sci. USA. 95:1998;3949-3953.
16. Shanabruch W.G., Behlau I., Walker G.C. Spontaneous mutators of Salmonella typhimurium LT2 generated by insertion of transposable elements. J. Bacteriol. 147:1981;827-835.
17. Liu H., Hewitt S.R., Hays J.B. Antagonism of ultraviolet-light mutagenesis by the methyl-directed mismatch-repair system of Escherichia coli. Genetics. 154:2000;503-512.
18. García del Portillo F., Pucciarelli M.G., Casadesús J. DNA adenine methylase mutants of Salmonella typhimurium show defects in protein secretion, cell invasion, and M cell cytotoxicity. Proc. Natl. Acad. Sci. USA. 96:1999;11578-11583.
19. Zahrt T.C., Buchmeier N., Maloy S. Effect of mutS and recD mutations on Salmonella virulence. Infect. Immun. 67:1999;6168-6172.
20. Mizrahi V., Andersen S.J. DNA repair in Mycobacterium tuberculosis. What have we learnt from the genome sequence? Mol. Microbiol. 29:1998;1331-1339.
21. Herrero M., de Lorenzo V., Timmis K.N. Transposon vectors containing non-antibiotic resistance selection markers for cloning and stable chromosomal insertion of foreign genes in gram-negative bacteria. J. Bacteriol. 172:1990;6557-6567.