Differential DNA hypermethylation of critical genes mediates the stage-specific tobacco smoke - Induced neoplastic progression of lung cancer

Clinical Cancer Research

Volumn 11, Issue 7, 2005, Pages 2466-2470

  Russo, Andrea L ^a   Thiagalingam, Arunthathi ^a   Pan, Hongjie ^a   Califano, Joseph ^b   Cheng, Kuang Hung ^a   Ponte, Jose F ^a   Chinnappan, Dharmaraj ^a   Nemani, Pratima ^a   Sidransky, David ^b   Thiagalingam, Sam ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEATH ASSOCIATED PROTEIN KINASE; DNA METHYLTRANSFERASE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE P1; METHYL GUANINE DNA METHYLTRANSFERASE; PROTEIN P16; SMAD8 PROTEIN; TOBACCO SMOKE; TUMOR MARKER; UNCLASSIFIED DRUG; UVOMORULIN;

ARTICLE; BRONCHUS MUCOSA; CANCER GROWTH; CIGARETTE SMOKING; CONTROLLED STUDY; DISEASE MARKER; DNA METHYLATION; EPITHELIUM CELL; FISHER EXACT TEST; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG CANCER; PERIPHERAL LYMPHOCYTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

APOPTOSIS REGULATORY PROTEINS; BRONCHI; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CADHERINS; CARCINOMA, NON-SMALL-CELL LUNG; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DISEASE PROGRESSION; DNA METHYLATION; DNA, NEOPLASM; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTATHIONE S-TRANSFERASE PI; GLUTATHIONE TRANSFERASE; HUMANS; ISOENZYMES; LUNG NEOPLASMS; MODELS, BIOLOGICAL; NEOPLASM STAGING; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; POLYMERASE CHAIN REACTION; PRECANCEROUS CONDITIONS; PROMOTER REGIONS (GENETICS); RESPIRATORY MUCOSA; SMAD8 PROTEIN; SMOKING; TRANS-ACTIVATORS; TUMOR MARKERS, BIOLOGICAL;

EID: 17644414480     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-04-1962     Document Type: Article

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