Serial killing of tumor cells by cytotoxic T cells redirected with a CD19-/CD3-bispecific single-chain antibody construct

International Journal of Cancer

Volumn 115, Issue 1, 2005, Pages 98-104

  Hoffmann, Patrick ^a   Hofmeister, Robert ^a   Brischwein, Klaus ^a   Brandl, Christian ^a   Crommer, Sandrine ^a   Bargou, Ralf ^b   Itin, Christian ^a   Prang, Nadja ^a   Baeuerle, Patrick A ^a  

^a MICROMET AG   (Germany)

^b Section of Pathology   (Germany)

Author keywords

Bispecific antibody; CD19; CD3; Cytotoxicity

Indexed keywords

CD19 ANTIGEN; CD3 ANTIGEN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ARTICLE; B CELL LYMPHOMA; B LYMPHOCYTE; CARCINOGENESIS; CELL ACTIVITY; CELL MOTILITY; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; POLYCLONAL ACTIVATION; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TARGET CELL; TUMOR CELL LINE;

ANTIBODIES, BISPECIFIC; ANTIGENS, CD19; ANTIGENS, CD3; B-LYMPHOCYTES; CELL LINE, TUMOR; CELL MEMBRANE; CELL NUCLEUS; CYTOTOXICITY, IMMUNOLOGIC; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HUMANS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOTHERAPY; INTERLEUKIN-2; KINETICS; LYMPHOCYTE ACTIVATION; MICROSCOPY, VIDEO; NEOPLASMS; T-LYMPHOCYTES; T-LYMPHOCYTES, CYTOTOXIC; TIME FACTORS;

EID: 17644385543     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20908     Document Type: Article

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