Retinal degeneration is delayed by tissue factor pathway inhibitor-2 in RCS rats and a sodium-iodate-induced model in rabbits

Eye

Volumn 19, Issue 4, 2005, Pages 464-468

  Obata, Ryo ^a,d   Yanagi, Y ^a   Tamaki, Y ^a   Hozumi, K ^b   Mutoh, M ^b   Tanaka, Y ^c  

^a UNIVERSITY OF TOKYO   (Japan)

^b TORAY INDUSTRIES INC   (Japan)

^c NATIONAL HOSPITAL ORGANIZATION TOKYO MEDICAL CENTER   (Japan)

^d SAITAMA RED CROSS HOSPITAL   (Japan)

Author keywords

Rabbit; Retinal degeneration; Retinal pigment epithelium; Royal Collage of Surgeons (RCS) rat; Sodium iodate; Tissue factor pathway inhibitor 2 (TFPI 2)

Indexed keywords

RECOMBINANT TISSUE FACTOR PATHWAY INHIBITOR; RECOMBINANT TISSUE FACTOR PATHWAY INHIBITOR 2; SODIUM IODATE; UNCLASSIFIED DRUG;

AMPLITUDE MODULATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C WAVE; CELL PROLIFERATION; CELL VACUOLE; CONTROLLED STUDY; DRUG MECHANISM; ELECTRORETINOGRAM; FIBROBLAST; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PHOTORECEPTOR CELL; PIGMENT EPITHELIUM; RABBIT; RAT; RETINA DEGENERATION; VASCULAR ENDOTHELIUM;

EID: 17544361943     PISSN: 0950222X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.eye.6701531     Document Type: Article

References (30)

1. Faktorovich EG, Steingerg RH, Yasumura D, Matthes MT, LaVail MM. Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor. Nature 1990; 347: 83-86.
2. Unoki K, LaVail MM. Protection of the rat retina from ischemic injury by brain-derived neurotrophic factor, ciliary neurotrophic factor, and basic fibroblast growth factor. Invest Ophthalmol Vis Sci 1994; 35: 907-915.
3. Sugarman BJ, Aggarwal BB, Hass PE, Figari IS, Palladino Jr MA, Shepard HM. Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro. Science 1985; 230: 943-945.
4. Abraham JA, Mergia A, Whang JL, Tumolo A, Friedman J, Hjerrild KA et al. Nucleotide sequence of a bovine clone encoding the angiogenic protein, basic fibroblast growth factor. Science 1986; 233: 545-548.
5. Sivalingam A, Kenney J, Brown GC, Benson WE, Donoso L. Basic fibroblast growth factor levels in the vitreous of patients with proliferative diabetic retinopathy. Arch Ophthalmol 1990; 108 869-872.
6. Cassidy L, Barry P, Shaw C, Duffy J, Kennedy S. Platelet derived growth factor and fibroblast growth factor basic levels in the vitreous of patients with vitreoretinal disorders. Br J Ophthalmol 1998; 82: 181-185.
7. Hueber A, Wiedemann P, Esser P, Heimann K. Basic fibroblast growth factor mRNA, bFGF peptide and FGF receptor in epiretinal membranes of intraocular proliferative disorders (PVR and PDR). Int Ophthalmol 1996-97; 20: 345-350.
8. Limb CA, Little BC, Meager A, Ogilvie JA, Wolstencroft RA, Franks WA, Chignell AH, Dumonde DC. Cytokines in proliferative vetreoretinopathy. Eye 1991; 5: 686-693.
9. D'Amore PA. Mechanisms of retinal and choroidal neovascularization. Invest Ophthalmol Vis Sci 1994; 35: 3974-3979.
10. Frank RN, Amin RH, Eliott D, Puklin JE, Abrams GW. Basic fibroblast growth factor and vascular endothelial growth factor are present in epiretinal and choroidal neovascular membranes. Am J Ophthalmol 1996; 122: 393-403.
11. Ogata N, Matsushima M, Takeda Y, Tobe T, Takahashi K, Yi X et al. Expression of basic fibroblast growth factor mRNA in developing choroidal neovascularization. Curr Eye Res 1996; 15: 1008-1018.
12. Kimura H, Sakamoto T, Hinton DR, Spee C, Ogura Y, Tabata Y et al. A new model of subretinal neovascularization in the rabbit. Invest Ophthalmol Vis Sci 1995; 36: 2110-2119.
13. Sprecher CA, Kisiel W, Mathewes S, Foster DC. Molecular cloning, expression, and partial characterization of a second human tissue-factor-pathway inhibitor. Proc Natl Acad Sci USA 1994; 91 3353-3357.
14. Shinoda E, Yui Y, Hattori R, Tanaka M, Inoue R, Aoyama T et al. Tissue factor pathway inhibitor-2 is a novel mitogen for vascular smooth muscle cells. J Biol Chem 1999; 274: 5379-5384.
15. Herman MP, Sukhova GK, Kiesiel W, Foster D, Kehry MR, Libby P et al. Tissue factor pathway inhibitor-2 is a novel inhibitor of matrix metalloproteinases with implication for atherosclerosis. J Clin Invest 2000; 107: 1117-1126.
16. Tanaka Y, Utsumi J, Sudo T, Matsui M, Sudo T, Nakamura N et al. Purification, molecular cloning and expression of a novel growth-promoting factor for retinal pigment epithelial cells, REF-1/TFPI-2. Invest Ophthalmol Vis Sci 2004; 45: 245-252.
17. Gal A, Li Y, Thompson DA, Weir J, Orth U, Jacobson SG et al. Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa. Nat Genet 2000; 26 270-271.
18. Gu SM, Thompson DA, Srikumari CR, Lorenz B, Finckh U, Nicoletti A et al. Mutations in RPE65 cause autosomal recessive childhood-onset severe retinal dystrophy. Nat Genet 1997; 17: 194-197.
19. D'Cruz PM, Yasumura D, Weir J, Matthes MT, Abderrahim H, LaVail MM et al. Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat. Hum Mol Genet 2000; 9 645-651.
20. Bok D, Hall MO. The role of the pigment epithelium in the etiology of inherited retinal dystrophy in the rat. J Cell Biol 1971; 49: 664-682.
21. Noell WK. Experimentally induced toxic effects on structure and function of visual cells and pigment epithelium. Am J Ophthalmol 1953; 36: 103-116.
22. Lurie M, Marmor MF. Similarities between the c-wave and slow PIII in the rabbit eye. Invest Ophthalmol Vis Sci 1980; 19: 1113-1117.
23. Noell WK. The origin of the electroretinogram. Am J Ophthalmol 1954; 38: 78-93.
24. Steinberg RH, Schmidt R, Brown KT. Intracellular responses to light from cat pigment epithelium: origin of the electroretinogram c wave. Nature 1970; 227: 728-730.
25. Oakley B, Green DG. Correlation of light-induced changes in retinal extracellular potassium concentration with c-wave of the electroretinogram. J Neurophysiol 1976; 39: 1117-1133.
26. Ringvold A, Olsen E, Flage T. Transient breakdown of the retinal pigment epithelium diffusion barrier after sodium iodate: a fluorescein angiographic and morphologic study in the rabbit. Exp Eye Res 1981; 33: 361-369.
27. Korte GE, Reppucci V, Henkind P. RPE destruction causes choriocapillary atrophy. Invest Ophthalmol Vis Sci 1984; 25: 1135-1145.
28. + - ATPase in regenerationg retinal pigment epithelium in the rabbit. A study by electron microscopic cytochemistry. Exp Eye Res 1993; 56: 219-229.
29. LaVail MM, Unoki K, Yasumura D, Matthes MT, Yancopoulos GD, Steinberg RH. Multiple growth factors, cytokines, and neurotorophins rescue photoreceptors from the damaging effects of constant light. Proc Natl Acad Sci USA 1992; 89: 11249-11253.
30. Karsan A, Yee E, Poirier GG, Zhou P, Craig R, Harlan JM. Fibroblast growth factor-2 inhibits endothelial cell apoptosis by Bcl-2-dependent and independent mechanisms. Am J Pathol 1997; 151: 1775-1784.