Dominicin, a cyclic octapeptide, and laughine, a bromopyrrole alkaloid, isolated from the Caribbean marine sponge Eurypon laughlini

Journal of Natural Products

Volumn 68, Issue 3, 2005, Pages 327-330

  Williams, David E ^a   Patrick, Brian O ^a   Behrisch, Hans W ^b   Van Soest, Rob ^c   Roberge, Michel ^a   Andersen, Raymond J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b ROSS UNIVERSITY SCHOOL OF MEDICINE   (Dominica)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AGELONGINE; ALKALOID DERIVATIVE; BROMOPYRROLE ALKALOID; CYCLIC OCTAPEPTIDE; CYCLOPEPTIDE; DOMINICIN; KERAMADINE; LAUGHINE; NATURAL PRODUCT; OCTAPEPTIDE; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG; ALKALOID;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL ASSAY; CELL STRAIN MCF 7; CENTRAL AMERICA; CHEMICAL BOND; CHIRALITY; COELENTERATE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DERIVATIZATION; DRUG DEGRADATION; DRUG HYDROLYSIS; DRUG ISOLATION; DRUG STRUCTURE; EURYPON LAUGHLINI; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; MASS SPECTROMETRY; MITOSIS INHIBITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; ULTRAVIOLET SPECTROSCOPY; X RAY DIFFRACTION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DOMINICA; ISOLATION AND PURIFICATION; NUCLEAR MAGNETIC RESONANCE; SPONGE (PORIFERA); X RAY CRYSTALLOGRAPHY;

EURYPON;

ALKALOIDS; ANIMALS; CRYSTALLOGRAPHY, X-RAY; DOMINICA; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDES, CYCLIC; PORIFERA; PYRROLES;

EID: 17444418296     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np049711r     Document Type: Article

References (10)

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10. Crystallographic data for the structure reported in this paper have been deposited with the Cambridge Crystallographic Data Centre (deposition number CCDC 258283). Copies of the data can be obtained, free of charge, on application to the Director, CCDC, 12 Union Road, Cambridge CB2 1EZ, UK (fax: +44-(0)1223-336033 or e-mail: deposit@ccdc.cam.ac.uk).