Physiological response of central metabolism in Escherichia coli to deletion of pyruvate oxidase and introduction of heterologous pyruvate carboxylase

Biotechnology and Bioengineering

Volumn 90, Issue 1, 2005, Pages 64-76

  Vemuri, G N ^a   Minning, T A ^b   Altman, E ^a   Eiteman, M A ^a  

^a University of Georgia   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

Acetate formation; Anaplerotic reaction; Gene expression microarray; Overflow metabolism

Indexed keywords

AMINO ACIDS; BIOASSAY; BIOSYNTHESIS; ENZYMES; GENES; GLUCOSE; METABOLISM; PHYSIOLOGICAL MODELS;

ENERGY METABOLISM; GENE EXPRESSION ANALYSIS; PYRUVATE CARBOXYLASE (PYC); PYRUVATE OXIDASE (POX);

ESCHERICHIA COLI;

ACETIC ACID; AMINO ACID; GLUCOKINASE; GLUCOSE; PHOSPHOTRANSFERASE; PYRUVATE CARBOXYLASE; PYRUVATE OXIDASE; PYRUVIC ACID;

AMINO ACID SYNTHESIS; ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL STRAIN; BACTERIUM CULTURE; BACTERIUM MUTANT; BIOACCUMULATION; CONTROLLED STUDY; CULTURE MEDIUM; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME ASSAY; ESCHERICHIA COLI; GENE DELETION; GENE EXPRESSION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GROWTH RATE; MICROBIAL BIOMASS; NONHUMAN; OXYGEN CONSUMPTION; PARAMETER; PROTEIN EXPRESSION; STEADY STATE; UPREGULATION; WILD TYPE;

ACETATES; CELL PROLIFERATION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; MULTIENZYME COMPLEXES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXYGEN; PROTEIN ENGINEERING; PYRUVATE CARBOXYLASE; PYRUVATE OXIDASE; PYRUVIC ACID;

EID: 17444415327     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.20418     Document Type: Article

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