Detection of volatile compounds emitted by Pseudomonas aeruginosa using selected ion flow tube mass spectrometry

Pediatric Pulmonology

Volumn 39, Issue 5, 2005, Pages 452-456

  Carrol, Will ^a   Lenney, Warren ^a   Wang, Tianshu ^b   Španěl, Patrik ^c   Alcock, Alice ^a   Smith, David ^b  

^a UNIVERSITY HOSPITAL OF NORTH STAFFORDSHIRE   (United Kingdom)

^b KEELE UNIVERSITY   (United Kingdom)

^c J HEYROVSKÝ INSTITUTE OF PHYSICAL CHEMISTRY   (Czech Republic)

Author keywords

Biomarkers; Hydrogen cyanide; Pseudomonas aeruginosa; SIFT MS

Indexed keywords

AGAR; BIOLOGICAL MARKER; VOLATILE AGENT;

ACCURACY; ADOLESCENT; ANALYTIC METHOD; ARTICLE; BACTERIAL FLORA; BACTERIAL GROWTH; BACTERIUM CULTURE; BACTERIUM ISOLATE; BREATH ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; CYSTIC FIBROSIS; GRAM NEGATIVE INFECTION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INOCULATION; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SELECTED ION FLOW TUBE MASS SPECTROMETRY; SENSITIVITY AND SPECIFICITY; SPUTUM SMEAR; UPPER RESPIRATORY TRACT;

ACETONITRILES; ADOLESCENT; ADULT; AMMONIA; BIOLOGICAL MARKERS; CHILD; CHILD, PRESCHOOL; COUGH; CULTURE MEDIA; CYSTIC FIBROSIS; DISULFIDES; FEASIBILITY STUDIES; HUMANS; HYDROGEN CYANIDE; MASS SPECTROMETRY; ODORS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; SENSITIVITY AND SPECIFICITY; SPUTUM; SULFHYDRYL COMPOUNDS;

EID: 17444404932     PISSN: 87556863     EISSN: None     Source Type: Journal    
DOI: 10.1002/ppul.20170     Document Type: Article

References (28)

1. Labarca J, Pegues D, Wagar E, Hindler J, Bruckner D. Something's rotten: a nosocomial outbreak of malodorous Pseudomonas aeruginosa. Clin Infect Dis 1998;26:1440-1446.
2. Menashe I, Man O, Lancet D, Gilad Y. Different noses for different people. Nat Genet 2003;34:143-144.
3. Cox CD, Parker J. Use of 2-aminoacetophenone production in identification of Pseudomonas aeruginosa. J Clin Microbiol 1979;9:479-484.
4. Zechman J, Aldinger S, Labows JN Jr. Characterization of pathogenic bacteria by automated headspace concentration-gas chromatography. J Chromatogr 1986;377:49-57.
5. Labows J, McGinley K, Webster G, Leyden J. Headspace analysis of volatile metabolites of Pseudomonas aeruginosa and related species by gas chromatography-mass spectrometry. J Clin Microbiol 1980;12:521-526.
6. Scholler C, Molin S, Wilkins K. Volatile metabolites from some Gram-negative bacteria. Chemosphere 1997;35:1487-1495.
7. Španěl P, Smith D. Application of ion chemistry and the SIFT technique to the quantitative analysis of trace gases in air and on breath. Int Rev Phys Chem 1996;15:231-271.
8. Španěl P, Smith D. The selected ion flow tube a novel technique for the quantitative trace gases analysis of air and human breath. Med Biol Eng Comput 1996;34:409-419.
9. Smith D, Španěl P. Selected ion flow tube mass spectrometry, SIFT-MS, for on-line trace gas analysis. Mass Spectrom Rev 2005; in press. Published online 19 October 2004.
10. Smith D, Španěl P. SIFT applications in mass spectrometry. In: Lindon J, Tranter G, Holmes J, editors. Encyclopedia of spectroscopy and spectrometry: mass spectrometry. London: Academic Press; 1999. p 2092-2105.
11. Smith D, Španěl P, Holland TA, Singary W, Elder JB. Selected ion flow tube mass spectrometry of urine headspace. Rapid Commun Mass Spectrom 1999;13:724-729.
12. Španěl P, Smith D, Holland TA, Singary W, Elder JB. Analysis of formaldehyde in the headspace of urine from bladder and prostate cancer patients using selected ion flow tube mass spectrometry. Rapid Commun Mass Spectrom 1999;13:1354-1359.
13. Abbott SM, Elder JB, Španěl P, Smith D. Quantification of acetonitrile in exhaled breath and urinary headspace using selected ion flow tube mass spectrometry. Int J Mass Spectrom 2003;228:655-665.
14. Smith D, Wang TS, Španěl P. Kinetics and isotope patterns of ethanol and acetaldehyde emissions from yeast fermentations of glucose and glucose-6,6-d2 using selected ion flow tube mass spectrometry: a case study. Rapid Commun Mass Spectrom 2002;16:69-76.
15. Smith D, Wang TS, Sulé-Suso J, Španěl P, El Haj A. Quantification of acetaldehyde released by lung cancer cells in vitro using selected ion flow tube mass spectrometry. Rapid Commun Mass Spectrom 2003;17:845-850.
16. Frederiksen B, Koch C, Hoiby N. Antibiotic treatment of initial colonization with Pseudomonas aeruginosa postpones chronic infection and prevents deterioration of pulmonary function in cystic fibrosis. Pediatr Pulmonol 1997;23:330-335.
17. Equi AC, Pike SE, Davies J, Bush A. Use of cough swabs in a cystic fibrosis clinic. Arch Dis Child 2001;85:438-439.
18. Goldfarb WB, Margraf H. Cyanide production by Pseudomonas aeruginosa. Ann Surg 1967;165:104-110.
19. Castric PA. Glycine metabolism by Pseudomonas aeruginosa: hydrogen cyanide biosynthesis. J Bacteriol 1977;130:826-831.
20. Castric PA, Eber RF, Castric KF. The relationship between growth phase and cyanogenesis in Pseudomonas aeruginosa. Curr Microbiol 1979;2:287-292.
21. Castric PA. Influence of oxygen on the Pseudomonas aeruginosa hydrogen cyanide synthase. Curr Microbiol 1994;29:19-21.
22. 2+ with compounds released by Pseudomonas and related bacteria. Int J Mass Spectrom 2004;233:245-251.
23. Worlitzsch D, Tarran R, Ulrich M, et al. Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients. J Clin Invest 2002;109:317-325.
24. Blumer C, Haas D. Mechanism, regulation and ecological role of bacterial cyanide biosynthesis. Arch Microbiol 2000;173:170-177.
25. Haas D, Blumer C, Keel C. Biocontrol ability of fluorescent Pseudomonas genetically dissected: importance of positive feedback regulation. Curr Opin Biotechnol 2000;11:290-297.
26. Lyczak JB, Cannon CL, Pier GB. Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist. Microbes Infect 2000;2:1051-1060.
27. Goldfarb WB, Magraf H. Cyanide production by Pseudomonas aeruginosa. Ann Surg 1967;165:104-110.
28. Singh PK, Schaefer AL, Parsek MR, Moninger TO, Welsh MJ, Greenberg EP. Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms. Nature 2000;407:762-764.