Dental caries, periodontal disease, and cardiac arrhythmias in community-dwelling older persons aged 80 and older: Is there a link?

Journal of the American Geriatrics Society

Volumn 53, Issue 3, 2005, Pages 430-437

  Holm Pedersen, Poul ^a,b   Avlund, Kirsten ^c   Morse, Douglas E ^d   Stoltze, Kaj ^b   Katz, Ralph V ^d   Viitanen, Matti ^e   Winblad, Bengt ^e  

^a Copenhagen Gerontological Oral Health Research Center ^*  (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d NEW YORK UNIVERSITY   (United States)

^e KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Arrhythmia; Cardiovascular disease; Elderly; Oral disease; Periodontal disease

Indexed keywords

AGED; AGING; ARTICLE; CONTROLLED STUDY; DENTAL CARIES; DISEASE ASSOCIATION; FEMALE; HEART ARRHYTHMIA; HUMAN; MALE; MEDICAL ASSESSMENT; MEDICAL EXAMINATION; MOUTH EXAMINATION; PERIODONTAL DISEASE; POPULATION RESEARCH; PUBLIC HEALTH; URBAN POPULATION; CHRONIC DISEASE; GERIATRICS; LONGITUDINAL STUDY; STATISTICAL MODEL; SWEDEN;

AGED; AGED, 80 AND OVER; ARRHYTHMIA; CHRONIC DISEASE; DENTAL CARIES; FEMALE; GERIATRICS; HUMANS; LOGISTIC MODELS; LONGITUDINAL STUDIES; MALE; PERIODONTAL DISEASES; SWEDEN; URBAN POPULATION;

EID: 17444393553     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/j.1532-5415.2005.53160.x     Document Type: Article

References (50)

1. Howell TH, Ridker PM, Ajani UA et al. Periodontal disease and risk of subsequent cardiovascular disease in U.S. male physicians. J Am Coll Cardiol 2001;37:445-450.
2. Hujoel PP, Drangsholt M, Spiekerman C et al. Examining the link between coronary heart disease and the elimination of chronic dental infections. J Am Dent Assoc 2001;132:883-889.
3. Hujoel PP, Drangsholt M, Spiekerman C et al. Pre-existing cardiovascular disease and periodontitis: A follow-up study. J Dent Res 2002;81:186-191.
4. Tuominen R, Reunanen A, Paunio M et al. Oral health indicators poorly predict coronary heart disease deaths. J Dent Res 2003;82:713-718.
5. Mattila KJ, Nieminen MS, Valtonen VV et al. Association between dental health and acute myocardial infarction. BMJ 1989;298:779-781.
6. Mattila KJ, Valle MS, Valtonen VV et al. Dental infections and coronary atherosclerosis. Atherosclerosis 1993;103:205-211.
7. DeStefano F, Anda RF, Kahn HS et al. Dental disease and risk of coronary heart disease and mortality. BMJ 1993;306:688-691.
8. Beck JD, Garcia R, Heiss G et al. Periodontal disease and cardiovascular disease. J Periodontol 1996;67:1123-1137.
9. Beck JD, Elter JR, Heiss G et al. Relationship of periodontal disease to carotid artery intima-media wall thickness: The Atherosclerosis Risk in Communities (ARIC) study. Arterioscler Thromb Vasc Biol 2001;21:1816-1822.
10. Joshipura KJ, Rimm EB, Douglass CW et al. Poor oral health and coronary heart disease. J Dent Res 1996;75:1631-1636.
11. Katz J, Chaushu G, Sharabi Y. on the association between hypercholesterolemia, cardiovascular disease and severe periodontal disease. J Clin Periodontol 2001;28:865-868.
12. Kolltveit KM, Eriksen HM. Is the observed association between periodontitis and atherosclerosis causal? Eur J Oral Sci 2001;109:2-7.
13. Persson RE, Hollender LG, Powell VL et al. Assessment of periodontal conditions and systemic disease in older subjects II. Focus on cardiovascular diseases. J Clin Periodontol 2002;29:803-810.
14. Lowe G, Woodward M, Rumley A et al. Total tooth loss and prevalent cardiovascular disease in men and women. Possible roles of citrus fruit consumption, vitamin C, and inflammatory and thrombotic variables. J Clin Epidemiol 2003;56:694-700.
15. Desvarieux M, Demmer RT, Rundek T et al. Relationship between periodontal disease, tooth loss, and carotid artery plaque. Stroke 2003;34:2120-2130.
16. Loos BG, Craandijk J, Hoek FJ et al. Elevation of systemic markers related to cardiovascular diseases in the peripheral blood of periodontitis patients. J Periodontol 2000;71:1528-1534.
17. Papapanou PN, Neiderud AM, Papadimitriu A et al. 'Checkerboard' assessments of periodontal microbiota and serum antibody responses: A case-control study. J Periodontol 2000;71:885-897.
18. Wu T, Trevisan M, Genco RJ et al. Examination of the relation between periodontal health status and cardiovascular risk factors: Serum total and high density lipoprotein cholesterol, C-reactive protein, and plasma fibrinogen. Am J Epidemiol 2000;151:273-282.
19. Slade GD, Ghezzi EM, Heiss G et al. Relationship between periodontal disease and C-reactive protein among adults in the Atherosclerosis Risk in Communities Study. Arch Intern Med 2003;163:1172-1179.
20. Janket S-J, Baird AE, Chuang S-K et al. Meta-analysis of periodontal disease and risk of coronary heart disease and stroke. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;95:559-569.
21. Mattila KJ, Asikainen S, Wolf J et al. Age, dental infections, and coronary heart disease. J Dent Res 2000;79:756-760.
22. Takata Y, Ansai T, Matsumura K et al. Relationship between tooth loss and electrocardiographic abnormalities in octogenarians. J Dent Res 2001;80: 1648-1652.
23. Mauriello SM, Lawrence HP, Beck JD. Risk modeling for root caries and mortality in older adults. IADR Abstract 896. J Dent Res 1996;Special Issue:75.
24. Mauriello SM, Beck JD, Elter JR. Root caries incidence as a risk predictor for mortality. IADR Abstract 3582. J Dent Res 1999;Special Issue:78.
25. Duncan AK, Vittone J, Fleming KC et al. Cardiovascular disease in elderly patients. Mayo Clin Proc 1996;71:184-196.
26. Van Gelder IC, Brügemann J, Crijns HJGM. Pharmacological management of arrhythmias in the elderly. Drugs Aging 1997;11:96-110.
27. Gupta AK, Maheshwari A, Tresch DD et al. Cardiac arrhythmias in the elderly. Cardiac Electrophys Rev 2002;6:120-128.
28. Falk RH. Etiology and complications of atrial fibrillation: Insights from pathology studies. Am J Cardiol 1998;82:10N-17N.
29. Ryder KM, Benjamin EJ. Epidemiology and significance of atrial fibrillation. Am J Cardiol 1999;84:131R-138R.
30. Kannel W, Abbot R, Safage D et al. Epidemiological features of chronic atrial fibrillation. The Framingham Study. N Engl J Med 1982;306:1018-1022.
31. Krahn AD, Manfreda J, Tate RB et al. The natural history of atrial fibrillation: Incidence, risk factors, and prognosis in the Manitoba Follow-up Study. Am J Med 1995;98:476-484.
32. Benjamin EJ, Wolf PA, D'Agostino RB et al. Impact of atrial fibrillation on the risk of death. The Framingham Heart Study. Circulation 1998;98: 946-952.
33. Davies MJ, Pomerance A. Pathology of atrial fibrillation in man. Br Heart J 1972;34:520-525.
34. Fratiglioni L, Viitanen M, Bäckman L et al. Occurrence of dementia in advanced age: The study design of the Kungsholmen Project. Neuroepidemiology 1992;11(Suppl 1):29-36.
35. Morse DE, Holm-Pedersen P, Holm-Pedersen J et al. Dental caries in persons over the age of 80 years living in Kungsholmen, Sweden: Findings from the KEOHS Project. Community Dent Health 2002;19:262-267.
36. Oral Health of United States Adults. The National Survey of Oral Health in U.S. Employed Adults and Seniors, 1985-1986, National Findings (NIH Publication no. 87-2868). Bethesda: National Institutes of Health, Public Health Service, U.S. Department of Health and Human Services, 1987.
37. Papapanou PN. Periodontal diseases: Epidemiology. Ann Periodontol 1996;1:1-36.
38. Carlos JP, Wolfe MD, Klingman A. The extent and severity index: A simple method for use in epidemiologic studies of periodontal disease. J Clin Periodontol 1986;13:500-505.
39. Beck JD, Koch GG, Rozier RG et al. Prevalence and risk indicators for periodontal attachment loss in a population of older community-dwelling blacks and whites. J Periodontol 1990;61:521-528.
40. Silver JG, Martin AW, McBride BC. Experimental transient bacteremias in human subjects with varying degrees of plaque accumulation and gingival inflammation. J Clin Periodontol 1977;4:92-94.
41. Guntheroth WG. How important are dental procedures as cause of infective endocarditis. Am J Cardiol 1984;54:797-801.
42. Gupta S, Leatham EW, Carrington D et al. Elevated Chlamydia pneumonia antibodies, cardiovascular events and azithromycin in male survivors of myocardial infarction. Circulation 1997;96:404-407.
43. Gurfinkel E, Bozovich G, Beck E et al. Treatment with antibiotic roxithromycin in patients with acuta non-Q-wave coronary syndromes. The final report of the ROXIS study. Eur Heart J 1999;20:121-127.
44. Ghuran AV, Camm AJ. Ischemic heart disease presenting as arrhythmias. Br Med Bull 2001;59:193-210.
45. Jette AM, Feldman HA, Douglas CW. Oral disease and physical disability in community-dwelling older persons. J Am Geriatr Soc 1993;41:1102-1108.
46. Avlund K, Holm-Pedersen P, Schroll M. Functional ability and oral health among older people: A longitudinal study from age 75 to 80. J Am Geriatr Soc 2001;49:954-962.
47. Avlund K, Holm-Pedersen P, Morse DE et al. Tooth loss and caries prevalence in very old Swedish people: The relationship to cognitive function and functional ability. Gerodontology 2004;21:17-26.
48. Morse DE, Holm-Pedersen P, Holm-Pedersen J et al. Prosthetic crowns and other clinical risk indicators of caries among old-old Swedish adults: Findings from the KEOHS Project. Gerodontology 2002;19:73-79.
49. Dawes CA. A mathematical model of salivary clearance from the oral cavity. Caries Res 1983;17:321-334.
50. Sreebny LM. Saliva-salivary gland hypofunction (SGH). FDI Working Group 10. J Dent Assoc S Afr 1992;47:498-501.