Synthesis and evaluation of a series of 2'-deoxy analogues of the antiviral agent 5,6-dichloro-2-isopropylamino-1-(β-L-ribofuranosyl)-1H- benzimidazole (1263W94)

Nucleosides, Nucleotides and Nucleic Acids

Volumn 19, Issue 1-2, 2000, Pages 101-123

  Chan, Joseph H ^a   Chamberlain, Stanley D ^a   Biron, Karen K ^a   Davis, Michelle G ^a   Harvey, Robert J ^a   Selleseth, Dean W ^a   Dornsife, Ronna E ^a   Dark, Ernest H ^a   Frick, Lloyd W ^a   Townsend, Leroy B ^b   Drach, John C ^b   Koszalka, George W ^a  

^a GLAXOSMITHKLINE   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 CYCLOROPYLAMINO 5,6 DICHLORO 1 (2 DEOXY BETA LEVO RIBOFURANOSYL)BENZIMIDAZOLE; 5,6 DICHLORO 2 CYCLOPENTYLAMINO 1 (2 DEOXY BETA LEVO RIBOFURANOSYL)BENZIMIDAZOLE; 5,6 DICHLORO 2 ISOROPYLAMINO 1 (2 DEOXY BETA LEVO RIBOFURANOSYL)BENZIMIDAZOLE; ANTIVIRUS AGENT; BENZIMIDAVIR; BENZIMIDAZOLE DERIVATIVE; CIDOFOVIR; FOSCARNET; GANCICLOVIR; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CYTOMEGALOVIRUS; CYTOTOXICITY; DNA HYBRIDIZATION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG HALF LIFE; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION;

CYTOMEGALOVIRUS; HUMAN HERPESVIRUS 5; STAPHYLOCOCCUS PHAGE 3A;

EID: 17344394256     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1080/15257770008032999     Document Type: Article

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