Autografting in Philadelphia (Ph)+ chronic myeloid leukaemia using cultured marrow: An update of a pilot study

Bone Marrow Transplantation

Volumn 19, Issue 10, 1997, Pages 969-976

  Coutinho, L H ^a   Chang, J ^a   Brereton, M L ^a   Morgenstern, G R ^a   Scarffe, J H ^a   Harrison, C J ^b   Liu Yin, J A ^a   Darbyshire, P J ^c   Burdach, S ^d   Dexter, T M ^a   Testa, N G ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b MANCHESTER ROYAL INFIRMARY   (United Kingdom)

^c BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

^d HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Autologous marrow transplantation; CML; LTBMC; Purging

Indexed keywords

HUMAN INTERFERON;

ADULT; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BONE MARROW CULTURE; CELL CLONE; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CLINICAL TRIAL; FEMALE; GRAFT FAILURE; HEMATOPOIESIS; HEMATOPOIETIC CELL; HUMAN; MALE; MORTALITY; PATIENT SELECTION; PHILADELPHIA 1 CHROMOSOME; PRIORITY JOURNAL; RECURRENT DISEASE; REMISSION; SCHOOL CHILD; SCREENING; TIME;

EID: 17344377232     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1700777     Document Type: Article

References (41)

1. Shtivelman E, Lifshitz B, Gale RP, Canaani E. Fused transcript of abl and bcr genes in chronic myelogenous leukaemia. Nature 1985; 315: 550-554.
2. Fialkow PJ, Jacobson RJ, Papayannopoulou T. Chronic myelocytic leukemia: clonal origin in a stem cell common to the granulocytic, erythrocytic, platelet and monocyte/ macrophage. Am J Med 1977; 63: 125-130.
3. Martin PJ, Najfeld V, Hansen JA et al. Involvement of the B-lymphoid system in chronic myelogenous leukaemia. Nature 1980; 287: 49-50.
4. Savage DG, Goldman JM. Approaches to the treatment of chronic myeloid leukemia. Int J Hematol 1994; 60: 1-21.
5. The Italian Cooperative Study Group on Chronic Myeloid Leukemia. Interferon alfa-2α as compared with conventional chemotherapy for the treatment of chronic myeloid leukemia. New Engl J Med 1994; 330: 820-825.
6. Allan NC, Richards SM, Shepherd PCA. UK Medical Research Council randomised, multicentre trial of interferon-αn1 for chronic myeloid leukaemia: improved survival irrespective of cytogenetic response. Lancet 1995; 345: 1392-1397.
7. Giralt S, Kantarjian H, Talpaz M. Treatment of chronic myelogenous leukemia. Semin Oncol 1995; 22: 396-404.
8. Clift RA, Buckner CD; Thomas ED et al. Marrow transplantation for chronic myeloid leukemia: a randomized study comparing cyclophosphamide and total body irradiation with busulfan and cyclophosphamide. Blood 1994; 84: 2036-2043.
9. Van Rhee F, Lin F, Cross NCP et al. Detection of residual leukaemia more than 10 years after allogeneic bone marrow transplantation for chronic myelogenous leukaemia. Bone Marrow Transplant 1994; 14: 609-612.
10. Spencer A, Szydlo RM, Brookes PA et al. Bone marrow transplantation for chronic myeloid leukaemia with volunteer unrelated donors using ex vivo or in vivo T-cell depletion: major prognostic impact of HLA class I identity between donor and recipient. Blood 1995; 86: 3590-3597.
11. McGlave PB, De Fabritiis P, Deisseroth A et al. Autologous transplants for chronic myelogenous leukaemia: results from eight transplant groups. Lancet 1994; 343: 1486-1488.
12. Fefer A, Radich J, Pavletic Z et al. Syngeneic bone marrow transplantation (BMT) for chronic myelogenous leukemia in chronic phase: update of the original 14 Seattle patients including PCR results. Blood 1994; 84 (Suppl. 1): 252a.
13. Deisseroth AB, Zu Z, Claxton D et al. Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML. Blood 1994; 83: 3068-3076.
14. Carella AM, Podesta M, Frassoni F et al. Collection of 'normal' blood repopulating cells during early hemopoietic recovery after intensive conventional chemotherapy in chronic myelogenous leukemia. Bone Marrow Transplant 1993; 12: 267-271.
15. McGlave PB, Arthur D, Miller WJ et al. Autologous transplantation for CML using marrow treated ex vivo with recombinant human interferon gamma. Bone Marrow Transplant 1990; 6: 115-120.
16. Carlo-Stella C, Mangoni L, Almici C et al. Autologous transplant for chronic myelogenous leukemia using marrow treated ex vivo with mafosfamide. Bone Marrow Transplant 1994; 14: 425-432.
17. Barnett MJ, Eaves CJ, Phillips GL et al. Autografting with cultured marrow in chronic myeloid leukemia: results of a pilot study. Blood 1994; 84: 724-732.
18. Coulombel L, Kalousek DK, Eaves CJ et al. Long-term marrow culture reveals chromosomally normal hematopoietic progenitor cells in patients with Philadelphia chromosome-positive chronic myelogenous leukemia. New Engl J Med 1983; 308: 1493-1498.
19. Udomsakdi C, Eaves CJ, Swolin B et al. Rapid decline of chronic myeloid leukemic cells in long-term culture due to a defect at the leukemic stem cell level. Proc Natl Acad Sci USA 1992; 89: 6192-6196.
20. Coutinho LH, Testa NG, Chang J et al. The use of cultured bone marrow cells in autologous transplantation. In: Gross A, Gee AP, Worthington-White DA (eds). Bone Marrow Purging and Processing. Alan R Liss: New York, 1990, pp 415-433.
21. Coutinho LH, Brereton ML, Santos AMW et al. Evaluation of cytogenetic conversion to Ph-haemopoiesis in long-term bone marrow culture for patients with chronic myeloid leukaemia on conventional hydroxyurea therapy, on pulse high-dose hydroxyurea and on interferon-alpha. Br J Haematol 1996; 93: 869-877.
22. Chang J, Coutinho LH, Harrison CJ et al. High-dose pulsed hydroxyurea treatment conserves Philadelphia chromosome negative (Ph(-)) haemopoiesis in chronic myeloid leukaemia. Br J Haematol 1989; 71 (Suppl. 1): 6.
23. Coutinho LH, Chang J, Testa NG, Dexter TM. Autologous bone marrow transplantation using cultured cells in patients with leukaemia. in: Testa NG, Molineux G (eds). Haemopoiesis. A Practical Approach. Oxford University Press: Oxford, 1993, pp 219-231.
24. Coutinho LH, Gilleece MH, De Wynter EA et al. Clonal and long-term cultures using human bone marrow. In: Testa NG, Molineux G (eds). Haemopoiesis. A Practical Approach. Oxford University Press: Oxford, 1993, pp 75-105.
25. Dube ID, Eaves CJ, Kalousek DK, Eaves AC. A method for obtaining high quality chromosome preparations from single hemopoietic colonies on a routine basis. Cancer Genet Cytogenet 1981; 4: 157-168.
26. Chang J, Coutinho LH, Morgenstern G et al. Reconstitution of haematopoietic system with autologous marrow taken during relapse of acute myeloblastic leukaemia and grown in long-term culture. Lancet 1986; i: 294-295.
27. Chang J, Morgenstern GR, Coutinho LH et al. The use of bone marrow cells grown in long-term culture for autologous bone marrow transplantation in acute myeloid leukaemia: an update. Bone Marrow Transplant 1989; 4: 5-9.
28. Barnett MJ, Eaves CJ, Phillips GL et al. Successful autografting in chronic myeloid leukaemia after maintenance of marrow in culture. Bone Marrow Transplant 1989; 4: 345-351.
29. Sutherland HJ, Lansdorp PM, Henkelman DH et al Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers. Proc Natl Acad Sci USA 1990; 87: 3584-3588.
30. Andrews NC, Singer JW, Berstein ID. Precursors of colony-forming cells in humans can be distinguished from colony-forming cells by expression of CD33 and CD34 antigens and light scatter properties. J Exp Med 1989; 169: 1721-1731.
31. Talpaz M, Kantarjian H, Liang J et al. Percentage of Philadelphia chromosome (Ph)-negative and Ph-positive cells found after autologous transplantation for chronic myelogenous leukemia depends on percentage of diploid cells induced by conventional dose chemotherapy before collection of autologous cells. Blood 1995; 85: 3257-3263.
32. Kuss BJ, Sage RE, Shepherd KM et al. High dose hydroxy-urea in collection of Philadelphia chromosome-negative stem cells in chronic myeloid leukaemia. Leuk Lymphoma 1993; 10: 73-78.
33. Brito-Babapulle F, Bowcock SJ, Marcus RE et al. Autografting for patients with chronic myeloid leukaemia in chronic phase: peripheral blood stem cells may have a finite capacity for maintaining haemopoiesis. Br J Haematol 1989; 73: 76-81.
34. Hoyle C, Gray R, Goldman J. Autografting for patients with CML in chronic phase: an update. Br J Haematol 1994; 86: 76-81.
35. Kantarjian HM, Talpaz M, Andersson B et al. High doses of cyclophosphamide, etoposide and total body irradiation followed by autologous stem cell transplantation in the management of patients with chronic myelogenous leukemia. Bone Marrow Transplant 1994; 14: 57-61.
36. Hunter MG, Bawden L, Brotherton D et al. BB-10010: an active variant of human macrophage inflammatory protein-1α with improved pharmaceutical properties. Blood 1995; 86: 4400-4408.
37. Bergamaschi G, Podesta M, Frassoni F et al. Restoration of normal polyclonal haemopoiesis in patients with chronic myeloid leukaemia autografted with Ph-negative peripheral stem cells. Br J Haematol 1994; 87: 867-870.
38. Mehta J, Mijovic A, Powles R et al. Myelosuppressive chemotherapy to mobilize normal stem cells in chronic myeloid leukemia. Bone Marrow Transplant 1996; 17: 25-29.
39. Horowitz MM, Gale RP, Sondel PM et al. Graft-versus-leukemia reactions after bone marrow transplantation. Blood 1990; 75: 555-562.
40. Scheffold C, Brandt K, Johnston V et al. Potential of autologous immunologic effector cells for bone marrow purging in patients with chronic myeloid leukemia. Bone Marrow Transplant 1995; 15: 33-39.
41. Massumoto C, Benyunes MC, Sale G et al. Close simulation of acute graft-versus-host disease by interleukin-2 administered after autologous bone marrow transplantation for hematologic malignancy. Bone Marrow Transplant 1996; 17: 351-356.