A practical technique for differentiation of subepidermal bullous diseases: Localization of in vivo-bound IgG by laser scanning confocal microscopy

Archives of Dermatology

Volumn 139, Issue 8, 2003, Pages 1007-1011

  Woźniak, Katarzyna ^a   Kazama, Takashi ^b   Kowalewski, Cezary ^a  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

^b NIIGATA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA4 INTEGRIN; COLLAGEN TYPE 4; FLUORESCEIN ISOTHIOCYANATE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; KALININ;

ADULT; ARTICLE; BULLOUS SKIN DISEASE; CLINICAL ARTICLE; CONFOCAL LASER MICROSCOPY; DIFFERENTIAL DIAGNOSIS; EPIDERMOLYSIS BULLOSA ACQUISITA; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOELECTRON MICROSCOPY; MALE; PEMPHIGOID; PRIORITY JOURNAL; PUNCH BIOPSY; SKIN BIOPSY; SKIN DISEASE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BASEMENT MEMBRANE; CHILD; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; EPIDERMIS; EPIDERMOLYSIS BULLOSA ACQUISITA; FEMALE; HUMANS; IMMUNOGLOBULIN G; MALE; MICROSCOPY, CONFOCAL; PEMPHIGOID, BENIGN MUCOUS MEMBRANE; PEMPHIGOID, BULLOUS; PROSPECTIVE STUDIES;

EID: 17344377015     PISSN: 0003987X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archderm.139.8.1007     Document Type: Article

References (24)

1. Bean SF. Cicatricial pemphigoid. In: Beutner E, Chorzelski TP, Kumar V, eds. Immunopathology of the Skin. 3rd ed. New York, NY: John Wiley & Sons Inc; 1987:355-360.
2. Gammon WR, Briggaman RA, Woodley DT, et al. Epidermolysis bullosa acquisita: a pemphigoid-like disease. J Am Acad Dermatol. 1984;11:820-832.
3. Roenigk HH, Ryan JG, Bergfeld WF. Epidermolysis bullosa acquisita: report of three cases and review of all published cases. Arch Dermatol. 1971;103:1-10.
4. Jordon RE, Beutner EH, Witebsky E, et al. Basement zone antibodies in bullous pemphigoid. JAMA. 1967;200:751-756.
5. Kushniruk W. The immunopathology of epidermolysis bullosa acquisita. Can Med Assoc J. 1973;108:1143-1146.
6. Bruckner-Tuderman L, Nilssen O, Zimmermann DR, et al. Immunohistochemical and mutation analysis demonstrate that procollagen VII is processed to collagen VII through removal of the NC-2 domain. J Cell Biol. 1995;131:551-559.
7. Giudice GJ, Emery DJ, Diaz LA. Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180. J Invest Dermatol. 1992;99:243-250.
8. Chan LS, Ahmed AR, Anhalt GJ, et al. Mucous membrane pemphigoid: definition, diagnostic criteria, pathogenic factors, medical treatment and prognostic indicators. Arch Dermatol. 2002;138:370-379.
9. Christophoridis S, Budinger L, Borradori L, et al. IgG, IgA and IgE autoantibodies against the ectodomain of BP180 in patients with bullous and cicatricial pemphigoid and linear IgA bullous dermatosis. Br J Dermatol. 2000;143:349-355.
10. Zillikens D. BP180 as the common autoantigen in blistering diseases with different clinical phenotypes. Keio J Med. 2002;51:21-28.
11. Shimizu H. New insights into the immunoultrastructural organization of cutaneous basement membrane zone molecules. Exp Dermatol. 1998;7:303-313.
12. Bedane C, McMillan JR, Balding SD, et al. Bullous pemphigoid and cicatricial pemphigoid antibodies react with ultrastructurally separable epitopes on the BP180 ectodomain. J Invest Dermatol. 1997;108:901-907.
13. Shimizu H, McDonald JM, Gunner DB, et al. Epidermolysis bullosa acquisita antigen and the carboxy terminus of type VII collagen have a common immunolocalization to anchoring fibrils and lamina densa of basement membrane. Br J Dermatol. 1990;122:577-585.
14. Shimizu H, Ishiko A, Masunaga T, et al. Most anchoring fibrils in human skin originate and terminate in the lamina densa. Lab Invest. 1997;76:753-763.
15. Holubar K, Wolff K, Konrad K, Beutner EH. Ultrastructural localization of immunoglobulins in bullous pemphigoid skin: employment of a new peroxidase-antiperoxidase multistep method. J Invest Dermatol. 1975;64:220-227.
16. Fine JD, Neises GR, Katz SI. Immunofluorescence and immunoeleotron microscopic studies in cicatricial pemphigoid. J Invest Dermatol. 1984;82:39-43.
17. Nieboer C, Boorsma DM, Woerdeman MJ, Kalsbeek GL. Epidermolysis bullosa acquisita: immunofluorescense, electron microscopic and immunoelectron microscopic studies in four patients. Br J Dermatol. 1980;102:383-392.
18. Kazama T, Yamamoto Y, Hashimoto T, Komai A, Ito M. Application of confocal laser scanning microscopy to differential diagnosis of bullous pemphigoid and epidermolysis bullosa acquisita. Br J Dermatol. 1998;138:593-601.
19. Kowalewski C. New Methods in Diagnosing of Atypical Bullous Diseases [doctoral thesis]. Warsaw, Poland: Medical University of Warsaw; 1988.
20. Kowalewski C, Haftek M, Cozzani E, et al. Cicatricial pemphigoid of mucous membranes vs epidermolysis bullosa acquisita with exclusive IgA linear deposits in the basement membrane zone. In: Ishibishi Y, Nagawa H, Suzuki H, eds. Electron Microscopy in Dermatology. Amsterdam, the Netherlands: Elsevier Science Publishers; 1994:187-193
21. Gammon WR, Kowalewski C, Chorzelski TP, et al. Immunofluorescence on sodium chloride-separated skin in the differential diagnosis of bullous pemphigoid and epidermolysis bullosa acquisita. J Am Acad Dermatol. 1990;22:664-670.
22. Lazarova Z, Hsu R, Briggaman RA, et al. Fab fragments directed against laminin-5 induce subepidermal blisters in neonatal mice. Clin Immunol. 2000;95:26-32.
23. Lazarova Z, Yee C, Lazar J, et al. IgG autoantibodies in patients with antiepiligrin cicatricial pemphigoid recognize the G domain of the laminin 5 alpha-subunit. Clin Immunol. 2001;101:100-105.
24. Bruins S, de Jong MC, Heeres K, Wilkinson MH, Jonkman MF, van der Meer JB. Fluorescence overlay antigen mapping of the epidermal basement membrane zone, I: geometric errors. J Histochem Cytochem. 1994;42:555-560.