Myelin basic protein induces cell death of mature pig oligodendrocytes in vitro and produces demyelination in vivo

Neuroscience Letters

Volumn 283, Issue 1, 2000, Pages 77-80

  Althaus, Hans H ^a   Klöppner, Sabine ^a   Rohde, Gerlinde ^a   Parvizi, Nahid ^b   Schwartz, Peter ^c   Brück, Wolfgang ^c   Holtz, Wolfgang ^c  

^a MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^b Inst of Anim Breed and Behaviour   (Germany)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Astrocytes; Cationic polypeptides; Demyelination; Myelin basic protein; Oligodendrocytes

Indexed keywords

MYELIN BASIC PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL DEATH; DEMYELINATION; MYELIN SHEATH; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SWINE; TISSUE SLICE;

ANIMALS; APOPTOSIS; AXONS; BRAIN; CELL CULTURE TECHNIQUES; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEINS; MYELIN SHEATH; OLIGODENDROGLIA; SWINE;

EID: 17344376761     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)00920-4     Document Type: Article

References (20)

1. Althaus H.H., Klöppner S., Poehling H.-M., Neuhoff V. Two-dimensional gel electrophoresis of myelin and oligodendroglial proteins solubilized by a mixture of tetramethylurea and dimethylethylenurea. Electrophoresis. 4:1983;347-353.
2. Althaus H.H., Montz H., Neuhoff V., Schwartz P. Isolation and cultivation of mature oligodendroglial cells. Naturwissenschaften. 71:1984;309-315.
3. Althaus H.H., Schmidt-Schultz T., Klöppner S. Mature pig astrocytes do not respond to NGF as oligodendrocytes do. Jeserich G., Althaus H.H., Richter-Landsberg C., Heumann R. Molecular Signaling and Regulation in Glial Cells. 1997;20-27 Springer, Berlin.
4. Arnold L.J., Dagan A., Gutheil J., Kaplan N.O. Antineoplastic activity of poly(L-lysine) with some ascites tumor cells. Proc. Natl. Acad. Sci. USA. 76:1979;3246-3250.
5. Benjamins J.A., Nedelkoska L. Release of intracellular calcium stores leads to retraction of membrane sheets and cell death in mature mouse oligodendrocytes. Neurochem. Res. 21:1996;471-479.
6. Bologa L., Deugnier M.-A., Joubert R., Bisconte J.-C. Myelin basic protein stimulates the proliferation of astrocytes: possible explanation for multiple sclerosis plaque formation. Brain Res. 346:1985;199-203.
7. i in regenerating mature oligodendroglial cells. NeuroReport. 5:1994;397-400.
8. Franklin R.J.M., Crang A.J., Blakemore W.F. The role of astrocytes in the remyelination of glia-free areas of demyelination. Adv. Neurol. 59:1993;125-130.
9. 2+/ cation influx in various cell types. Biochem. J. 331:1998;623-630.
10. Graça D.L., Blakemore W.F. Delayed remyelination in rat spinal cord following ethidium bromide injection. Neuropath. Appl. Neurobiol. 12:1986;593-605.
11. Hall S.M. The effect of injections of lysophosphatidyl choline into the white matter of the adult mouse spinal cord. J. Cell. Sci. 13:1972;257-277.
12. Harrison B. Schwann cell and oligodendrocyte remyelination in lysolecithin induced lesions in irradiated rat spinal cord. J. Neurol. Sci. 67:1985;243-259.
13. Jeffery N.D., Blakemore W.F. Locomotor deficits induced by experimental spinal cord demyelination are abolished by spontaneous remyelination. Brain. 120:1997;27-37.
14. Morrell P. Myelin. 1984;Plenum Press, New York.
15. Pinheiro T.J.T. The interaction of horse heart cytochrome c with phospholipid bilayers, structural and dynamic effects. Biochimie. 76:1994;489-500.
16. Salemme F.R. Structure and function of cytochrome c. Ann. Rev. Biochem. 46:1977;299-329.
17. Sil M., Chatterjee D., Sarkar P.K. Comparative analysis of the membrane proteins and their specificities in neurons, protoplasmic astrocytes, and oligodendrocytes from rat brain. Neurochem Res. 11:1986;1181-1191.
18. Tzeng S.-F., Deibler G.E., deVries G.H. Exogenous myelin basic protein promotes oligodendrocyte death via increased calcium influx. J. Neurosci. Res. 42:1995;768-774.
19. 2+ mobilization. Am. J. Physiol. 274:1998;L997-L1005.
20. Yajima K., Suzuki K. Demyelination and remyelination in the rat central nervous system following ethidium bromide injection. Lab. Invest. 41:1979;385-392.