An opposing time-dependent immune-modulating effect of the sympathetic nervous system conferred by altering the cytokine profile in the local lymph nodes and spleen of mice with type II collagen-induced arthritis

Arthritis and Rheumatism

Volumn 52, Issue 4, 2005, Pages 1305-1313

  Härle, Peter ^a   Möbius, Daniel ^a   Carr, Daniel J J ^b   Schölmerich, Jürgen ^a   Straub, Rainer H ^a  

^a UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^b UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 3; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; TUMOR NECROSIS FACTOR ALPHA;

ADRENERGIC SYSTEM; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC ARTHRITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IMMUNIZATION; IMMUNOMODULATION; IMMUNOSTIMULATION; LYMPH NODE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; SYMPATHECTOMY; SYNOVIUM; TIME;

ANIMALS; ARTHRITIS, EXPERIMENTAL; CHEMOTAXIS, LEUKOCYTE; COLLAGEN TYPE II; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; JOINTS; LYMPH NODES; MICE; MICE, INBRED DBA; SPLEEN; SYMPATHECTOMY, CHEMICAL; SYMPATHETIC NERVOUS SYSTEM; SYNOVIAL MEMBRANE; TIME FACTORS;

EID: 17244381423     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.20987     Document Type: Article

References (37)

1. Selye H, Fortier C. Adaptive reactions to stress. Res Publ Assoc Res Nerv Ment Dis 1949;29:3-18.
2. Levine JD, Goetzl EJ, Basbaum AI. Contribution of the nervous system to the pathophysiology of rheumatoid arthritis and other polyarthritides. Rheum Dis Clin North Am 1987;13:369-83.
3. 2-adrenergic mechanisms in experimental arthritis. Proc Natl Acad Sci U S A 1988;85:4553-6.
4. Johnson HM, Archer DL, Torres BA. Cyclic GMP as the second messenger in helper cell requirement for γ-interferon production. J Immunol 1982;129:2570-2.
5. Novogrodsky A, Patya M, Rubin AL, Stenzel KH. Agents that increase cellular cAMP inhibit production of interleukin-2, but not its activity. Biochem Biophys Res Commun 1983;114:93-8.
6. Renz H, Gong JH, Schmidt A, Nain M, Gemsa D. Release of tumor necrosis factor-α from macrophages: enhancement and suppression are dose-dependently regulated by prostaglandin E2 and cyclic nucleotides. J Immunol 1988;141:2388-93.
7. 2 differentially modulates cytokine secretion profiles of human T helper lymphocytes. J Immunol 1993;150:5321-9.
8. Coderre TJ, Chan AK, Helms C, Basbaum AI, Levine JD. Increasing sympathetic nerve terminal-dependent plasma extravasation correlates with decreased arthritic joint injury in rats. Neuroscience 1991;40:185-9.
9. Lorton D, Lubahn C, Klein N, Schaller J, Bellinger DL. Dual role for noradrenergic innervation of lymphoid tissue and arthritic joints in adjuvant-induced arthritis. Brain Behav Immun 1999;13:315-34.
10. Harle P, Pongratz G, Straub RH. The sympathetic nervous system stimulates collagen-induced arthritis (CIA) in the induction phase and inhibits CIA in the late effector phase in DBA-1 mice [abstract]. Arthritis Rheum 2003;48 Suppl 9:S350.
11. Lubahn CL, Schaller JA, Bellinger DL, Sweeney S, Lorton D. The importance of timing of adrenergic drug delivery in relation to the induction and onset of adjuvant-induced arthritis. Brain Behav Immun 2004;18:563-71.
12. Miller LE, Justen HP, Scholmerich J, Straub RH. The loss of sympathetic nerve fibers in the synovial tissue of patients with rheumatoid arthritis is accompanied by increased norepinephrine release from synovial macrophages. FASEB J 2000;14:2097-107.
13. Miller LE, Grifka J, Scholmerich J, Straub RH. Norepinephrine from synovial tyrosine hydroxylase positive cells is a strong indicator of synovial inflammation in rheumatoid arthritis. J Rheumatol 2002;29:427-35.
14. Levine JD, Dardick SJ, Roizen MF, Helms C, Basbaum AI. Contribution of sensory afferents and sympathetic efferents to joint injury in experimental arthritis. J Neurosci 1986;6:3423-9.
15. Lewis T. The nocifensor system of nerves and its reactions. Br Med J 1937;194:491-4.
16. Szolcsanyi J. Neurogenic inflammation: reevaluation of axon reflex theory. In: Geppetti P, Holzer P, editors. Neurogenic inflammation. Boca Raton (FL): CRC Press; 1996. p. 33-42.
17. Geppetti P, Holzer P. Neurogenic inflammation. Boca Raton (FL): CRC Press; 1996.
18. Schaible HG, Grubb BD. Afferent and spinal mechanisms of joint pain. Pain 1993;55:5-54.
19. Konttinen YT, Kemppinen P, Segerberg M, Hukkanen M, Rees R, Santavirta S, et al. Peripheral and spinal neural mechanisms in arthritis, with particular reference to treatment of inflammation and pain [review]. Arthritis Rheum 1994;37:965-82.
20. Janig W, Levine JD, Michaelis M. Interactions of sympathetic and primary afferent neurons following nerve injury and tissue trauma. Prog Brain Res 1996;113:161-84.
21. Naveilhan P, Hassani H, Lucas G, Blakeman KH, Hao JX, Xu XJ, et al. Reduced antinociception and plasma extravasation in mice lacking a neuropeptide Y receptor. Nature 2001;409:513-7.
22. Dhabhar FS, McEwen BS. Bidirectional effects of stress and glucocorticoid hormones on immune function: possible explanations for paradoxical observations. In: Ader R, Felten DL, Cohen N, editors. Psychoneuroimmunology. San Diego: Academic Press; 2001. p. 301-38.
23. Madden KS, Felten SY, Felten DL, Sundaresan PR, Livnat S. Sympathetic neural modulation of the immune system. I. Depression of T cell immunity in vivo and vitro following chemical sympathectomy. Brain Behav Immun 1989;3:72-89.
24. Leo NA, Callahan TA, Bonneau RH. Peripheral sympathetic denervation alters both the primary and memory cellular immune responses to herpes simplex virus infection. Neuroimmunomodulation 1998;5:22-35.
25. 2-adrenergic agonist salbutamol potentiates oral induction of tolerance, suppressing adjuvant arthritis and antigen-specific immunity. J Immunol 2002;169:5028-35.
26. Li X, Taylor S, Zegarelli B, Shen S, O'Rourke J, Cone RE. The induction of splenic suppressor T cells through an immune-privileged site requires an intact sympathetic nervous system. J Neuroimmunol 2004;153:40-9.
27. Pacheco-Lopez G, Niemi MB, Kou W, Bildhauser A, Gross CM, Goebel MU, et al. Central catecholamine depletion inhibits peripheral lymphocyte responsiveness in spleen and blood. J Neurochem 2003;86:1024-31.
28. Maestroni GJ, Conti A. Noradrenergic modulation of lymphohematopoiesis. Int J Immunopharmacol 1994;16:117-22.
29. Rice PA, Boehm GW, Moynihan JA, Bellinger DL, Stevens SY. Chemical sympathectomy alters numbers of splenic and peritoneal leukocytes. Brain Behav Immun 2002;16:62-73.
30. Madden KS, Moynihan JA, Brenner GJ, Felten SY, Felten DL, Livnat S. Sympathetic nervous system modulation of the immune system. III. Alterations in T and B cell proliferation and differentiation in vitro following chemical sympathectomy. J Neuroimmunol 1994;49:77-87.
31. Esquifino AI, Castrillon PO, Chacon F, Cutrera R, Cardinali DP. Effect of local sympathectomy on 24-h changes in mitogenic responses and lymphocyte subset populations in rat submaxillary lymph nodes during the preclinical phase of Freund's adjuvant arthritis. Brain Res 2001;888:227-34.
32. 2-adrenergic agonist salbutamol is a potent suppressor of established collagen-induced arthritis: mechanisms of action. J Immunol 1999;162:6278-83.
33. Rantapaa-Dahlqvist S, de Jong BA, Berglin E, Hallmans G, Wadell G, Stenlund H, et al. Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis. Arthritis Rheum 2003;48:2741-9.
34. Pereira da Silva JA, Carmo-Fonseca M. Peptide containing nerves in human synovium: immunohistochemical evidence for decreased innervation in rheumatoid arthritis. J Rheumatol 1990;17:1592-9.
35. Miller LE, Weidler C, Falk W, Angele P, Schaumburger J, Scholmerich J, et al. Increased prevalence of semaphorin 3C, a repellent of sympathetic nerve fibers, in the synovial tissue of patients with rheumatoid arthritis. Arthritis Rheum 2004;50:1156-63.
36. Dekkers JC, Geenen R, Godaert GL, Bijlsma JW, Doornen LJ. Sympathetic and parasympathetic nervous system activity at night in patients with recently diagnosed rheumatoid arthritis. In: Dekkers JC, editor. Psychophysiological responsiveness in recently diagnosed patients with rheumatoid arthritis [thesis]. Dordrecht: Dekkers; 2003. p. 55-74.
37. Cronstein BN. The mechanism of action of methotrexate. Rheum Dis Clin North Am 1997;23:739-55.