Molecular characterization of a fucosyltransferase encoded by Schistosoma mansoni

Molecular and Biochemical Parasitology

Volumn 93, Issue 2, 1998, Pages 237-250

  Marques Jr , E T A ^a   Weiss, J B ^b   Strand, M ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ROCHE MOLECULAR SYSTEMS   (United States)

Author keywords

Fucose; Fucosyltransferase; Glycobiology; Schistosoma mansoni; Sialyl Lewis(X)

Indexed keywords

FUCOSYLTRANSFERASE;

ARTICLE; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME ASSAY; GENE EXPRESSION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SCHISTOSOMA MANSONI;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD15; BASE SEQUENCE; BLOTTING, SOUTHERN; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; DNA, COMPLEMENTARY; FUCOSYLTRANSFERASES; GENES, HELMINTH; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; OLIGOSACCHARIDES; OPEN READING FRAMES; SCHISTOSOMA MANSONI; TRANSFECTION;

EID: 17144460862     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(98)00033-4     Document Type: Article

References (51)

1. [1] Cummings RD, Nyame AK. Glycobiology of schistosomiasis. FASEB J 1996;10:838-48.
2. [2] Nyame K, Cummings RD, Damian RT. Characterization of the N-and O -linked oligosaccharides in glycoproteins synthesized by Schistosoma mansoni schistosomula. J Parasitol 1988;74:562-72.
3. [3] Ko AI, Drager UC, Harn DA. A Schistosoma mansoni epitope recognized by a protective monoclonal antibody is identical to the stage-specific embryonic antigen 1. Proc Natl Acad Sci USA 1990;87:4159-63.
4. [4] Van Dam GJ, Bergwerff AA, Thomas-Oates JE, Rotmans JP, Kamerling JP, Vliegenthart JF, Deelder AM. The immunologically reactive O -linked polysaccharide chains derived from circulating cathodic antigen isolated from the human blood fluke Schistosoma mansoni have Lewis x as repeating unit. Eur J Biochem 1994;225:467-82.
5. [5] Srivatsan J, Smith DF, Cummings RD. The human blood fluke Schistosoma mansoni synthesizes glycoproteins containing the Lewis X antigen. J Biol Chem 1992;267:20196-203.
6. [6] Khoo KH, Sarda S, Xu X, Caulfield JP, McNeil MR, Homans SW, Morris HR, Dell A. A unique multifucosylated -3Ga1NAc beta 1 → 4G1cNAc beta 1 → 3Ga1 alpha 1-motif constitutes the repeating unit of the complex O-glycans derived from the cercarial glycocalyx of Schistosoma mansoni. J Biol Chem 1995;270:17114-23.
7. [7] Levery SB, Weiss JB, Salyan ME, Roberts CE, Hakomori S, Magnani JL, Strand M. Characterization of a series of novel fucose-containing glycosphingolipid immunogens from eggs of Schistosoma mansoni. J Biol Chem 1992;267:5542-51.
8. [8] Lowe JB. Molecular cloning, expression, and uses of mammalian glycosyltransferases. Semin Cell Biol 1991;2:289-307.
9. [9] Natsuka S, Gersten KM, Zenita K, Kannagi R, Lowe JB. Molecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant [published erratum]. J Biol Chem 1994;269:20806.
10. [10] Natsuka S, Gersten KM, Zenita K, Kannagi R, Lowe JB. Molecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant. J Biol Chem 1994;269:16789-94.
11. [11] Weston BW, Smith PL, Kelly RJ, Lowe JB. Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes. J Biol Chem 1992;267:24575-84.
12. [12] Weston BW, Nair RP, Larsen RD, Lowe JB. Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities. J Biol Chem 1992;267:4152-60.
13. [13] Kukowska-Latallo JF, Larsen RD, Nair RP, Lowe JB. A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha(1,3/1,4)fucosyltransferase. Genes Dev 1990;4:1288-303.
14. [14] Lowe JB, Kukowska-Latallo JF, Nair RP, Larsen RD, Marks RM, Macher BA, Kelly RJ, Ernst LK. Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion. J Biol Chem 1991;266:17467-77.
15. [15] Sasaki K, Kurata K, Funayama K, Nagata M, Watanabe E, Ohta S, Hanai N, Nishi T. Expression cloning of a novel alpha 1,3-fucosyltransferase that is involved in biosynthesis of the sialyl Lewis x carbohydrate determinants in leukocytes. J Biol Chem 1994;269:14730-7.
16. [16] Oulmouden A, Wierinck A, Petit J, Costache M, Palcic M, Mollicone R, Oriol R, Julien R. Molecular cloning and expression of a bovine alpha(1,3)-fucosyltransferase gene homologous to a putative ancestor gene of the human Fut3-Fut5-Fut6 cluster. J Biol Chem 1997;272:8764-73.
17. [17] Smith PL, Gersten KM, Petryniak B, Kelly RJ, Rogers C, Natsuka Y, Alford JAR, Scheidegger EP, Natsuka S, Lowe JB. Expression of the alpha(1,3)fucosyltransferase Fuc-TVII in lymphoid aggregate high endothelial venules correlates with expression of L-selectin ligands. J Biol Chem 1996;271:8250-9.
18. [18] DeBose-Boyd R, Nyame AK, Cummings RD. Schistosoma mansoni: characterization of an alpha 1-3 fucosyltransferase in adult parasites. Exp Parasitol 1996;82:1-10.
19. x), a target of the antibody response in mice vaccinated with irradiated cercaria of Schistosoma mansoni. Infect Immun 1996;64:1826-31.
20. [20] Harn DA, Mitsuyama M, David JR. Schistosoma mansoni. Anti-egg monoclonal antibodies protect against cercarial challenge in vivo. J Exp Med 1984;159:1371-87.
21. [21] Grzych JM, Dissous C, Capron M, Torres S, Lambert PH, Capron A. Schistosoma mansoni shares a protective carbohydrate epitope with keyhole limpet hemocyanin. J Exp Med 1987;165:865-78.
22. [22] Omer Ali P, Smithers SR, Bickle Q, Phillips SM, Harn D, Simpson AJ. Analysis of the anti-Schistosoma mansoni surface antibody response during murine infection and its potential contribution to protective immunity. J Immunol 1988;140:3273-9.
23. [23] Nyame AK, Pilcher JB, Tsang VC, Cummings RD. Schistosoma mansoni infection in humans and primates induces cytolytic antibodies to surface Le(x) determinants on myeloid cells. Exp Parasitol 1996;82:191-200.
24. [24] Trottein F, Nutten S, Papin J, Leportier C, Poleain-Godefroy O, Capron A, Capron M. Roles of adhesion molecules of the selectin-carbohydrate families antibody-dependent cell-mediated cytoxicity to schistosome targets. J Immunol 1997;159:804-11.
25. [25] Weiss JB, Aronstein WS, Strand M. Schistosoma mansoni: stimulation of artificial granuloma formation in vivo by carbohydrate determinants. Exp Parasitol 1987;64:228-36.
26. [26] El Ridi R, Velupillai P, Harn DA. Regulation of schistosome egg granuloma formation: host-soluble L-selectin enters tissue-trapped eggs and binds to carbohydrate antigens on surface membranes of miracidia. Infect Immun 1996;64:4700-5.
27. [27] Hawn TR, Strand M. Developmentally regulated localization and phosphorylation of SmIrV1, a Schistosoma mansoni antigen with similarity to calnexin. J Biol Chem 1994;269:20083-9.
28. [28] Weiss JB, Strand M. Characterization of developmentally regulated epitopes of Schistosoma mansoni egg glycoprotein antigens. J Immunol 1985;135:1421-9.
29. [29] Koster B, Strand M. Schistosoma mansoni: immunolocalization of two different fucose-containing carbohydrate epitopes. Parasitology 1994;108:433-46.
30. [30] Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual, 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
31. [31] An SF, Franklin D, Fleming KA. Generation of digoxigenin-labelled double-stranded and single-stranded probes using the polymerase chain reaction. Mol Cell Probes 1992;6:193-200.
32. [32] Holtke HJ, Sagner G, Kessler C, Schmitz G. Sensitive chemiluminescent detection of digoxigenin-labeled nucleic acids: a fast and simple protocol and its applications. Biotechniques 1992;12:104-13.
33. [33] Holtke HJ, Seibl R, Burg J, Muhlegger K, Kessler C. Non-radioactive labeling and detection of nucleic acids. II. Optimization of the digoxigenin system. Biol Chem Hoppe Seyler 1990;371:929-38.
34. [34] Wynn TA, Eltoum I, Cheever AW, Lewis FA, Gause WC, Sher A. Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni. J Immunol 1993;151:1430-40.
35. [35] Wynn TA, Eltoum I, Oswald IP, Cheever AW, Sher A. Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J Exp Med 1994;179:1551-61.
36. [36] Norden AP, Strand M. Identification of antigenic Schistosoma mansoni glycoproteins during the course of infection in mice and humans. Am J Trop Med Hyg 1985;34:495-507.
37. [37] Hawn TR, Tom TD, Strand M. Molecular cloning and expression of SmIrV1, a Schistosoma mansoni antigen with similarity to calnexin, calreticulin, and OvRa11. J Biol Chem 1993;268:7692-8.
38. [38] Guo MM, Hildreth JE. HIV-induced loss of CD44 expression in monocytic cell lines. J Immunol 1993;151(4):2225-36.
39. [39] Kozak M. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 1986;44:283-92.
40. [40] Simpson AJ, Smithers SR. Characterization of the exposed carbohydrates on the surface membrane of adult Schistosoma mansoni by analysis of lectin binding. Parasitology 1980;81:1-15.
41. [41] Simpson AJ, Correa-Oliveira R, Smithers SR, Sher A. The exposed carbohydrates of schistosomula of Schistosoma mansoni and their modification during maturation in vivo. Mol Biochem Parasitol 1983;8:191-205.
42. [42] McDiarmid SS, Podesta RB. Identification of a sialic acid containing glycocalyx on the surface of Schistosoma mansoni. Mol Biochem Parasitol 1984;10:33-43.
43. [43] Robertson NP, Cain GD. Isolation and characterization of glycosaminoglycans from Schistosoma mansoni. Comp Biochem Physiol [B] 1985;82:299-306.
44. [44] Weiss J, Magnani JL, Strand M. Identification of Schistosoma mansoni glycolipids that share immunogenic carbohydrate epitopes with glycoproteins. J Immunol 1986;136:4275-82.
45. [45] Maly P, Thall A, Petryniak B, Rogers CE, Smith PL, Marks RM, Kelly RJ, Gersten KM, Cheng G, Saunders TL, Camper SA, Camphausen RT, Sullivan FX, Isogai Y, Hindsgaul O, von Andrian UH, Lowe JB. The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Cell 1996;86:643-53.
46. [46] Clarke JL, Watkins W. Alphal,3-L-fucosyltransferase expression in developing human myeloid cells. Antigenic, enzymatic, and mRNA analyses. J Biol Chem 1996;271:10317-28.
47. [47] La Marer N, Palcic MM, Clarke JL, Davies D, Skacel PO. Developmental regulation of alpha 1,3-fucosyltransferase expression in CD34 positive progenitors and maturing myeloid cells isolated from normal human bone marrow. Glycobiology 1997;7:357-65.
48. x expression in haemopoietic cells. Adv Exp Med Biol 1995;376:83-93.
49. [49] Masteller EL, Larsen RD, Carlson LM, Pickel JM, Nickoloff B, Lowe J, Thompson CB, Lee KP. Chicken B cells undergo discrete developmental changes in surface carbohydrate structure that appear to play a role in directing lymphocyte migration during embryogenesis. Development 1995;121:1657-67.
50. [50] Masteller EL, Lee KP, Carlson LM, Thompson CB. Expression of sialyl Lewis(x) and Lewis(x) defines distinct stages of chicken B cell maturation. J Immunol 1995;155:5550-6.
51. [51] Goelz S, Kumar R, Potvin B, Sundaram S, Brickelmaier M, Stanley P. Differential expression of an E-selectin ligand (SLex) by two Chinese hamster ovary cell lines transfected with the same alpha (1,3)-fucosyltransferase gene (ELFT). J Biol Chem 1994;269:1033-40.