Schistosoma mansoni infection in humans and primates induces cytolytic antibodies to surface Lex determinants on myeloid cells

Experimental Parasitology

Volumn 82, Issue 2, 1996, Pages 191-200

  Nyame, A Kwame ^a   Pilcher, Joy B ^b   Tsang, Victor C W ^b   Cummings, Richard D ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

CCA, circulating cathodic antigen; Complement dependent cytolysis; FucTIV, fucosyltransferase IV; HBSS, Hank's balanced salt solution; Helminthic parasite; Lewis x; NGS, normal goat serum; Schistosoma hematobium; Schistosoma japonicum; Schistosoma mansoni

Indexed keywords

CAPRA HIRCUS; MACACA MULATTA; PRIMATES; SCHISTOSOMA HAEMATOBIUM; SCHISTOSOMA JAPONICUM; SCHISTOSOMA MANSONI;

IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; PARASITE ANTIGEN;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CELL STRAIN HL 60; CONTROLLED STUDY; CYTOLYSIS; HUMAN; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; SERUM;

ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, CD15; COMPLEMENT SYSTEM PROTEINS; CYTOTOXICITY, IMMUNOLOGIC; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMANS; IMMUNE SERA; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LEUKEMIA, PROMYELOCYTIC, ACUTE; MACACA MULATTA; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; TUMOR CELLS, CULTURED;

EID: 0029906378     PISSN: 00144894     EISSN: None     Source Type: Journal    
DOI: 10.1006/expr.1996.0024     Document Type: Article

References (19)

1. BERGQUIST, N. R. 1995. Controlling schistosomiasis by vaccination: A realistic option? Parasitology Today 11, 191-194.
2. BICKLE, Q. D., AND FORD, M. J. 1982. Studies on the surface antigenicity and susceptibility to antibody-dependent killing of developing schistosomula using sera from chronically infected mice and mice vaccinated with irradiated cercariae. Journal of Immunology 128, 2101-2106.
3. BOROJEVIC, R., SANTOS-DA SILVA, C., AND CARVALHO, E. A. 1983. Chronic Schistosomiasis mansoni: Splenic myelopoiesis and inhibition of neutrophil granulocytopoiesis mediated by sera of patients. Journal of Infectious Disease 148, 422-426.
4. FOX, N., DAMIANOV, I., KNOWLES, B. B., AND SOLTER, D. 1983. Immunohistochemical localization of the mouse stage-specific embryonic antigen 1 in human tissues and tumors. Cancer Research 43, 669-678.
5. GOELZ, S. E., HESSION, C., GOFF, D., GRIFFITHS, B., TIZARD, R., NEWMAN, B., CHI-ROSSO, G., AND LOBB, R. 1990. ELFT: A gene that directs the expression of an ELAM-1 ligand. Cell 63, 1349-1356.
6. GRAY, G. R. 1974. The direct coupling of oligosaccharides to proteins and derivatized gels. Archives of Biochemistry and Biophysics 163, 426-428.
7. KO, A. I., DRÄGER, U. C., AND HARN, D. A. 1990. A Schistosoma mansoni epitope recognized by a protective monoclonal antibody is identical to the stage-specific embryonic antigen 1. Proceedings of the National Academy of Science of the United States of America 87, 4159-4163.
8. KÖSTER, B., AND STRAND, M. 1994. Schistosoma mansoni: Immunolocalization of two different fucose-containing carbohydrate epitopes. Parasitology 108, 433-446.
9. KUMAR, R., POTVIN, B., MULLER, W. A., AND STANLEY, P. 1991. Cloning of a human α(1,3)-fucosyltransferase gene that encodes ELFT but does not confer ELAM-1 recognition on Chinese hamster ovary cell transfectants. Journal of Biological Chemistry 266, 21777-21783.
10. LOBB, R. R., CHI-ROSSO, G., LEONE, D. R., ROSA, D., BIXLER, S., NEWMAN, B. M., LUHOWSKYJ, S., BENJAMIN, C. D., DOUGAS, I. G., GOELZ, S. E., HESSION, C., AND CHOW, E. P. 1991. Expression and functional characterization of a soluble form of endothelial-leukocyte adhesion molecule 1. Journal of Immunology 147, 124-129.
11. LOWE, J. B., KUKOWSKA-LATALLO, J. F., NAIR, R. P., LARSEN, R. D., MARKS, R. M., MACHER, B. A., KELLY, R. J., AND ERNST, L. K. 1991. Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion. Journal of Biological Chemistry 266, 17467-17477.
12. MCEVER, R. P., MOORE, K. L., AND CUMMINGS, R. D. 1995. Leukocyte trafficking mediated by selectin-carbohydrate interactions. Journal of Biological Chemistry 270, 11025-11026.
13. MOORE, K. L., AND THOMPSON, L. F. 1992. P-selectin (CD62) binds to subpopulations of human memory T lymphocytes and natural killer cells. Biochemical and Biophysical Research Communications 186, 173-181.
14. NYAME, K., CUMMINGS, R. D., AND DAMIAN, R. T. 1988. Characterization of the N-and O-Linked oligosaccharides in glycoproteins synthesized by Schistosoma mansoni schistosomula. Journal of Parasitology 74, 562-572.
15. SMITHERS, S. R., AND TERRY, R. J. 1976. The immunology of schistosomiasis. Advances in Parasitology 14, 399-411.
16. SMITHERS, S. R., MCLAREN, D. J., AND RAMALHO-PINTO, F. J. 1977. Immunity to schistosomes: The target. American Journal of Tropical Medicine and Hygiene 26, 11-17.
17. SRIVATSAN, J., SMITH, D. F., AND CUMMINGS, R. D. 1992. The human blood fluke Schistosoma mansoni synthesizes glycoproteins containing the Lewis x antigen. Journal of Biological Chemistry 267, 20196-20203.
18. VAN DAM, G. J., BERGWERFF, A. A., THOMAS-OATES, J. E., ROTMANS, J. P., KAMERLING, J. P., VLIEGENTHART, J. F. G., AND DEELDER, A. M. 1994. The immunologically reactive O-linked polysaccharide chains derived from circulating cathodic antigen isolated from the human blood fluke Schistosoma mansoni have Lewis X as repeating unit. European Journal of Biochemistry 225, 467-482.
19. VELUPILLAI, P., AND HARN, D. A. 1994. Oligosaccharide-specific induction of interleukin 10 production by B220+ cells from schistosome-infected mice: A mechanism for regulation of CD4+ T-cell subsets. Proceedings of the National Academy of Science of the United States of America 91, 18-22.