Copper blocks quinolinic acid neurotoxicity in rats: Contribution of antioxidant systems

Free Radical Biology and Medicine

Volumn 35, Issue 4, 2003, Pages 418-427

  Santamaría, Abel ^a   Flores Escartín, Abigail ^a   Martínez, Juan Carlos ^a   Osorio, Laura ^a   Galván Arzate, Sonia ^a   Chaverrí, José Pedraza ^b   Maldonado, Perla D ^b   Medina Campos, Omar N ^b   Jiménez Capdeville, María E ^a,c   Manjarrez, Joaquín ^a   Ríos, Camilo ^a  

^a NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^b Universidad Nacional Autonoma de Mexico Facultad de Quimica   (Mexico)

^c UNIVERSIDAD AUTÓNOMA DE SAN LUIS POTOSÍ   (Mexico)

Author keywords

Copper sulfate; Free radicals; Neurotoxicity; NMDA receptor; Oxidative stress; Quinolinic acid; Rat striatum

Indexed keywords

4 AMINOBUTYRIC ACID; CERULOPLASMIN; COPPER SULFATE; LACTATE DEHYDROGENASE; QUINOLINIC ACID; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CEREBROSPINAL FLUID; CIRCLING BEHAVIOR; CONTROLLED STUDY; CORPUS STRIATUM; DEPLETION; DOSE RESPONSE; DRUG EFFECT; DRUG MEGADOSE; ENZYME ACTIVITY; ENZYME ASSAY; IN VIVO STUDY; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPID PEROXIDATION; LOW DRUG DOSE; MALE; MORTALITY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; TREATMENT OUTCOME;

EID: 17144448614     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(03)00317-4     Document Type: Article

References (59)

1. Linder M.C., Hazegh-Azam M. Copper biochemistry and molecular biology. Am. J. Clin. Nutr. 63:1996;797S-811S.
2. Gutteridge J.M., Wilkins S. Copper salt-dependent hydroxyl radical formation. Damage to proteins acting as antioxidants. Biochim. Biophys. Acta. 759:1983;38-41.
3. Weiser T., Wienrich M. The effects of copper ions on glutamate receptors in cultured rat cortical neurons. Brain Res. 742:1996;211-218.
4. Hartmann H.A., Evenson M.A. Deficiency of copper can cause neuronal degeneration. Med. Hypotheses. 38:1992;75-85.
5. Rajan K.S., Colburn R.W., Davis J.M. Distribution of metal ions in the subcellular fractions of several rat brain areas. Life Sci. 18:1976;423-431.
6. A receptor-channel complex by polyvalent cations in rat dorsal root ganglion neurons. Brain Res. 607:1993;222-232.
7. Sadee W., Pfeiffer A., Herz A. Opiate receptors multiple effects of metal ions . J. Neurochem. 39:1982;659-667.
8. Schwarcz R., Foster A.C., French E.D., Whetsell W.O. Jr. Köhler, C. Excitotoxic models for neurodegenerative disorders. Life Sci. 35:1984;29-38.
9. Stone T.W. Neuropharmacology of quinolinic and kynurenic acids. Pharmacol. Rev. 45:1993;309-379.
10. Schwarcz R., Whetsell W.O. Jr., Mangano R.M. Quinolinic acid an endogenous metabolite that produces axon-sparing lesions in rat brain . Science. 219:1983;316-318.
11. Beal M.F., Kowall N.W., Ellison D.W., Mazurek M.F., Swartz K.J., Martin J.B. Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature. 321:1986;168-171.
12. Hantraye P., Riche D., Maziere M., Isacson O. A primate model of Huntington's disease behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon . Exp. Neurol. 108:1990;91-104.
13. Ferrante R.J., Kowall N.W., Cipolloni P.B., Storey E., Beal M.F. Excitotoxin lesions in primates as a model for Huntington's disease histopathologic and neurochemical characterization . Exp. Neurol. 119:1993;46-71.
14. Foster A.C., Collins J.F., Schwarcz R. On the excitotoxic properties of quinolinic acid, 2,3-piperidine dicarboxylic acids and structurally related compounds. Neuropharmacology. 22:1983;1331-1342.
15. During M.J., Heyes M.P., Freese A., Markey S.P., Martin J.B., Roth R.H. Quinolinic acid concentrations in striatal extracellular fluid reach potentially neurotoxic levels following systemic L-tryptophan loading. Brain Res. 476:1989;384-387.
16. Ríos C., Santamaría A. Quinolinic acid is a potent lipid peroxidant in rat brain homogenates. Neurochem. Res. 16:1991;1139-1143.
17. Santamaría A., Ríos C. MK-801, an N-methyl-D-aspartate receptor antagonist, blocks quinolinic acid-induced lipid peroxidation in rat corpus striatum. Neurosci. Lett. 159:1993;51-54.
18. Moroni F., Lombardi G., Carla V., Pellegrini D., Carassale G.L., Cortesini C. Content of quinolinic acid and of other tryptophan metabolites increases in brain regions of rats used as experimental models of hepatic encephalopaty. J. Neurochem. 46:1986;869-874.
19. Stone T.W., Connick J.H. Quinolinic acid and other kynurenines in the central nervous system. Neuroscience. 15:1985;597-617.
20. Schwarcz R., Okuno E., White R.J., Bird E.D., Whetsell W.O. Jr. 3-Hydroxyanthranilate oxygenase activity is increased in the brains of Huntington disease victims. Proc. Natl. Acad. Sci. USA. 85:1988;4079-4081.
21. Heyes M.P., Lackner A. Increased cerebrospinal fluid quinolinic acid, kynurenic acid, and L-kynurenine in acute septicemia. J. Neurochem. 55:1990;338-341.
22. Heyes M.P., Mefford I.N., Quearry B.J., Dedhia M., Lackner A. Increased ratio of quinolinic acid to kynurenic acid in cerebrospinal fluid of D retrovirus-infected Rhesus macaques relationship to clinical and viral status . Ann. Neurol. 27:1990;666-675.
23. Heyes M.P., Saito K., Crowley J.S., Davis L.E., Demitrack M.A., Der M., Dilling L.A., Elia J., Kruesi M.J., Lackner A., Larsen S.A., Lee K., Leonard H.L., Markey S.P., Martin A., Milstein S., Mouradian M.M., Pranzatelli M.R., Quearry B.J., Salazar A., Smith M., Strauss S.E., Sunderland T., Swedo S.W., Tourtellotte W.W. Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. Brain. 115:1992;1249-1273.
24. Ogawa T., Matson W.R., Beal M.F., Myers R.H., Bird E.D., Milbury P., Saso S. Kynurenine pathway abnormalities in Parkinson's disease. Neurology. 42:1992;1702-1706.
25. Štípek S., Št'astný F., Plátení k J., Crkovská J., Zima T. The effect of quinolinate on rat brain lipid peroxidation is dependent on iron. Neurochem. Int. 30:1997;233-237.
26. Behan W.M., McDonald M., Darlington L.G., Stone T.W. Oxidative stress as a mechanism for quinolinic acid-induced hippocampal damage protection by melatonin and deprenyl . Br. J. Pharmacol. 128:1999;1754-1760.
27. Cabrera J., Reiter R.J., Tan D.X., Qi W., Sainz R.M., Mayo J.C., García J.J., Kim S.J., El-Sokkary G. Melatonin reduces oxidative neurotoxicity due to quinolinic acid in vitro and in vivo findings . Neuropharmacology. 39:2000;507-514.
28. Santamaría A., Jiménez-Capdeville M.E., Camacho A., Rodríguez-Martínez E., Flores A., Galván-Arzate S. In vivo hydroxyl radical formation after quinolinic acid infusion into rat corpus striatum. Neuroreport. 12:2001;2693-2696.
29. Santamaría A., Ríos C., Pérez P., Flores A., Galván-Arzate S., Osorio-Rico L., Solís F. Quinolinic acid neurotoxicity in vivo increased copper and manganese content in rat corpus striatum after quinolinate intrastriatal injection . Toxicol. Lett. 87:1996;113-119.
30. Vlachová V., Zemková H., Vyklický L. Jr. Copper modulation of NMDA responses in mouse and rat cultured hippocampal neurons. Eur. J. Neurosci. 8:1996;2257-2264.
31. Coyle J.T., Puttfarcken P. Oxidative stress, glutamate and neurodegenerative disorders. Science. 262:1993;689-695.
32. Olney J.W., Labruyere J., Price M.T. Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science. 244:1989;1360-1362.
33. Levy D.I., Sucher N.J., Lipton S.A. Glutathione prevents N-methyl-D-aspartate receptor-mediated neurotoxicity. Neuroreport. 2:1991;345-347.
34. Santamaría A., Ríos C., Solís-Hernández F., Ordaz-Moreno J., González-Reynoso L., Altagracia M., Kravzov J. Systemic DL-kynurenine and probenecid pretreatment attenuates quinolinic acid-induced neurotoxicity in rats. Neuropharmacology. 35:1996;23-28.
35. Messripour M., Haddady H. Effect of ascorbic acid administration on copper-induced changes of rat brain hypothalamic catecholamine contents. Acta Neurol. Scand. 77:1988;481-485.
36. Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 1998;Academic Press, New York.
37. Welz B. Atomic absorption spectroscopy. 1976;Verlag-Chemie, New York.
38. Norman A.B., Wyatt L.M., Hildebrand J.P., Kolmonpunporn M., Moody C.A., Lehman M.N., Sanberg P.R. Sensitization of rotation behavior in rats with unilateral 6-hydroxydopamine or kainic acid-induced striatal lesions. Pharmacol. Biochem. Behav. 37:1990;755-759.
39. Fleury M.O., Ashley D.V. High-performance liquid chromatography analysis of amino acids in physiological fluids on line precolumn derivatization with o-phthaldialdehyde . Anal. Biochem. 133:1983;330-335.
40. Smith R.J., Panico K.A. Automated analysis of o-phtalaldehyde derivatives of amino acids in physiological fluids by reverse phase high performance liquid chromatography. J. Liq. Chromatogr. 8:1985;1783-1795.
41. 2+ injection. J. Neurochem. 42:1984;976-979.
42. Braughler J.M., Duncan L.A., Chase R.L. The involvement of iron in lipid peroxidation. Importance of ferric to ferrous ratios in initiation. J. Biol. Chem. 261:1986;10282-10289.
43. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin-phenol reagent. J. Biol. Chem. 193:1951;265-275.
44. Oberley L.W., Spitz D.R. Assay of superoxide dismutase activity in tumor tissue. Methods Enzymol. 105:1984;457-464.
45. Iqbal J., Whitney P. Use of cyanide and diethyldithiocarbamate in the assay of superoxide dismutases. Free Radic. Biol. Med. 10:1991;69-77.
46. Tanabe S., Shioiri T., Murakami K., Imanari T. A new method for assay of ferroxidase activity and its application to human and rabbit sera. Chem. Pharm. Bull. (Tokyo). 32:1984;4029-4035.
47. Pedraza-Chaverri J., Cruz C., Tapia E., Pena J.C. Activity of serum enzymes in puromycin aminonucleoside-induced nephrotic syndrome. Ren. Fail. 14:1992;523-531.
48. Siegel S. Non parametric statistics for the behavioral sciences. 1980;McGraw-Book Company, New York.
49. Steel R.G.D., Torrie J.H. Principles and procedures of statistics. 1980;McGraw-Hill Inc, New York.
50. Crowe A., Morgan E.H. Iron and copper interact during their uptake and deposition in the brain and other organs of developing rats exposed to dietary excess of the two metals. J. Nutr. 126:1996;183-194.
51. Rodríguez-Martínez E., Camacho A., Maldonado P.D., Pedraza-Chaverrí J., Santamaría D., Galván-Arzate S., Santamaría A. Effect of quinolinic acid on endogenous antioxidants in rat corpus striatum. Brain Res. 858:2000;436-439.
52. Cruz-Aguado R., Francis-Turner L., Díaz C.M., Antúnez I. Quinolinic acid lesion induces changes in rat striatal glutathione metabolism. Neurochem. Int. 37:2000;53-60.
53. Goda K., Kishimoto R., Shimizu S., Hamane Y., Ueda M. Quinolinic acid and active oxygens. Possible contribution of active oxygens during cell death in the brain. Adv. Exp. Med. Biol. 398:1996;247-254.
54. Iwahashi H., Kawamori H., Fukushima K. Quinolinic acid, α-picolinic acid, fusaric acid, and 2,6-pyridinedicarboxylic acid enhance the Fenton reaction in phosphate buffer. Chem. Biol. Interact. 118:1999;201-215.
55. Murakami K., Ueda T., Morikawa R., Ito M., Haneda M., Yoshino M. Antioxidant effect of dipicolinic acid on the metal-catalyzed lipid peroxidation and enzyme inactivation. Biomed. Res. 19:1998;205-208.
56. Tian L., Lawrence D.A. Metal-induced modulation of nitric oxide production in vitro by murine macrophages lead, nickel and cobalt utilize different mechanisms . Toxicol. Appl. Pharmacol. 141:1996;540-547.
57. Lafon-Cazal M., Culcasi M., Gaven F., Pietri S., Bockaert J. Nitric oxide, superoxide and peroxynitrite putative mediators of NMDA-induced cell-death in cerebellar granule cells . Neuropharmacology. 32:1993;1259-1266.
58. Santamaría D., Espinoza-González V., Ríos C., Santamaría A. Nω-nitro-L-arginine, a nitric oxide synthase inhibitor, antagonizes quinolinic acid-induced neurotoxicity and oxidative stress in rat striatal slices. Neurochem. Res. 24:1999;843-848.
59. Pérez-Severiano F., Escalante B., Ríos C. Nitric oxide synthase inhibition prevents acute quinolinate-induced striatal neurotoxicity. Neurochem. Res. 23:1998;1297-1302.