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Volumn 14, Issue 2, 2005, Pages 159-168

Inhibition of two stage renal carcinogenesis, oxidative damage and hyperproliterative response by Nigella sativa

Author keywords

Chemoprevention; Ferric nitrilotriacetate; Nigella sativa; Oxidative stress; Renal carcinogenesis

Indexed keywords

CREATININE; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; HYDROGEN PEROXIDE; NIGELLA SATIVA EXTRACT; NITRILOTRIACETATE IRON; ORNITHINE DECARBOXYLASE; POTASSIUM BROMATE; THYMIDINE; TRITIUM; XANTHINE OXIDASE;

EID: 17144404169     PISSN: 09598278     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008469-200504000-00012     Document Type: Article
Times cited : (75)

References (52)
  • 1
    • 0035099029 scopus 로고    scopus 로고
    • Antitumor promoting activity of Asteracantha long/folia against experimental hepatocarcinogenesis in rats
    • Ahmed S, Rahman A, Mathur M, Athar M, Sultana S (2001). Antitumor promoting activity of Asteracantha long/folia against experimental hepatocarcinogenesis in rats. Food Chem Toxicol 39: 19-28.
    • (2001) Food Chem Toxicol , vol.39 , pp. 19-28
    • Ahmed, S.1    Rahman, A.2    Mathur, M.3    Athar, M.4    Sultana, S.5
  • 2
    • 0038559976 scopus 로고    scopus 로고
    • Pharmacological and toxicological properties of Nigella saliva
    • Ali BH, Blunden G (2003). Pharmacological and toxicological properties of Nigella saliva. Phytother Res 17: 299-305.
    • (2003) Phytother Res , vol.17 , pp. 299-305
    • Ali, B.H.1    Blunden, G.2
  • 3
    • 0031841827 scopus 로고    scopus 로고
    • Thymoquinone protects against doxorubicin-induced cardiotoxicity without compromising its anti-tumor activity
    • Al-Shabanah OA, Badary OA, Nagi MN, et al. (1998). Thymoquinone protects against doxorubicin-induced cardiotoxicity without compromising its anti-tumor activity. J Exp Clin Cancer Res 17: 193-198.
    • (1998) J Exp Clin Cancer Res , vol.17 , pp. 193-198
    • Al-Shabanah, O.A.1    Badary, O.A.2    Nagi, M.N.3
  • 4
    • 0021835704 scopus 로고
    • A review of the environmental and mammalian toxicology of nitrilotriacetic acid
    • Anderson RL, Bishop WE, Campbell RL (1985). A review of the environmental and mammalian toxicology of nitrilotriacetic acid. Crit Rev Toxicol 15: 1-102.
    • (1985) Crit Rev Toxicol , vol.15 , pp. 1-102
    • Anderson, R.L.1    Bishop, W.E.2    Campbell, R.L.3
  • 5
    • 0344734121 scopus 로고
    • Oral anti-inflammatory and anti-ulcerogenic activities of a hydroalcoholic extract and partitioned fraction of Turnera ulmifolia (Turneaceae)
    • Antonio A, Souza A, Brito RM (1988). Oral anti-inflammatory and anti-ulcerogenic activities of a hydroalcoholic extract and partitioned fraction of Turnera ulmifolia (Turneaceae). J Ethnopharmacol 61: 215-228.
    • (1988) J Ethnopharmacol , vol.61 , pp. 215-228
    • Antonio, A.1    Souza, A.2    Brito, R.M.3
  • 6
    • 0031878395 scopus 로고    scopus 로고
    • Ferric nitrilotriacetate promotes N-diethylnitrosamine-induced renal tumorigenesis in the rats: Implications for the involvement of oxidative stress
    • Athar M, Iqbal M (1998). Ferric nitrilotriacetate promotes N-diethylnitrosamine-induced renal tumorigenesis in the rats: implications for the involvement of oxidative stress. Carcinogenesis 19: 1133-1139.
    • (1998) Carcinogenesis , vol.19 , pp. 1133-1139
    • Athar, M.1    Iqbal, M.2
  • 7
    • 0029785375 scopus 로고    scopus 로고
    • Coordination of copper polyamines complex with immidiozoles potentiates its superoxide dismutase mimicking activity and abolishes its interactions with albumin
    • Athar M, Sharma SD, Iqbal M, et al. (1996). Coordination of copper polyamines complex with immidiozoles potentiates its superoxide dismutase mimicking activity and abolishes its interactions with albumin. Biochem Mol Biol Int 39: 813-821.
    • (1996) Biochem Mol Biol Int , vol.39 , pp. 813-821
    • Athar, M.1    Sharma, S.D.2    Iqbal, M.3
  • 8
    • 0018358875 scopus 로고
    • Induction of diabetes in animals by parenteral administration of ferric nitrilotriacetate. A model of experimental hemochromatosis
    • Awai M, Narasaki M, Yamanoi Y, Seno S (1979). Induction of diabetes in animals by parenteral administration of ferric nitrilotriacetate. A model of experimental hemochromatosis. Am J Pathol 95: 663-672.
    • (1979) Am J Pathol , vol.95 , pp. 663-672
    • Awai, M.1    Narasaki, M.2    Yamanoi, Y.3    Seno, S.4
  • 9
    • 0031431309 scopus 로고    scopus 로고
    • Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity
    • Badary OA, Nagi MN, Al-Shabanah OA, et al. (1997). Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity. Can J Physiol Pharmacol 75: 1356-1361.
    • (1997) Can J Physiol Pharmacol , vol.75 , pp. 1356-1361
    • Badary, O.A.1    Nagi, M.N.2    Al-Shabanah, O.A.3
  • 10
    • 0019142866 scopus 로고
    • Increase of NADPH, quinone reductase activity by dietary antioxidant: Possible role in protection against carcinogenesis and toxicity
    • Benson AM, Hunkalar MJ, Talalay P (1980). Increase of NADPH, quinone reductase activity by dietary antioxidant: Possible role in protection against carcinogenesis and toxicity. Proc Natl Acad Sci USA 77: 5116-5220.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 5116-5220
    • Benson, A.M.1    Hunkalar, M.J.2    Talalay, P.3
  • 11
    • 0026888485 scopus 로고
    • A role for antioxidants in reducing cancer risk
    • Block G (1992). A role for antioxidants in reducing cancer risk. Nutr Rev 50: 207-213.
    • (1992) Nutr Rev , vol.50 , pp. 207-213
    • Block, G.1
  • 12
    • 0000473076 scopus 로고
    • Glutathione level in rat brain
    • Carlberg I, Mannervik B (1975). Glutathione level in rat brain. J Biol Chem 250: 4575-4580.
    • (1975) J Biol Chem , vol.250 , pp. 4575-4580
    • Carlberg, I.1    Mannervik, B.2
  • 15
    • 0023686219 scopus 로고
    • Mechanism of inhibition of mutagenesis and carcinogenesis: Classification and Overview
    • De Flora S, Ramel C (1988). Mechanism of inhibition of mutagenesis and carcinogenesis: Classification and Overview. Mutat Res 202: 285-306.
    • (1988) Mutat Res , vol.202 , pp. 285-306
    • De Flora, S.1    Ramel, C.2
  • 16
    • 0000232853 scopus 로고
    • Antimicrobial activity of aerial parts of Drossera pelitata Smith on oral bacteria
    • Didry N, Duberwil L, Tratin F, Pinkas M (1988). Antimicrobial activity of aerial parts of Drossera pelitata Smith on oral bacteria. J Ethnopharmacol 60: 215-228.
    • (1988) J Ethnopharmacol , vol.60 , pp. 215-228
    • Didry, N.1    Duberwil, L.2    Tratin, F.3    Pinkas, M.4
  • 17
    • 0036277862 scopus 로고    scopus 로고
    • Nigella saliva oil, nigellone and derived thymoquinone inhibit synthesis of 5-lipoxygenase products in polymorphonuclear leukocytes from rats
    • El-Dakhakhny M, Madi NJ, Lembert N, Ammon HP (2002). Nigella saliva oil, nigellone and derived thymoquinone inhibit synthesis of 5-lipoxygenase products in polymorphonuclear leukocytes from rats. J Ethnopharmacol 81: 161-164.
    • (2002) J Ethnopharmacol , vol.81 , pp. 161-164
    • El-Dakhakhny, M.1    Madi, N.J.2    Lembert, N.3    Ammon, H.P.4
  • 18
    • 0347272990 scopus 로고
    • An improved diphenyl method for the estimation of deoxyribonucleic acid
    • Giles KW, Myers A (1965). An improved diphenyl method for the estimation of deoxyribonucleic acid. Nature 206: 93.
    • (1965) Nature , vol.206 , pp. 93
    • Giles, K.W.1    Myers, A.2
  • 19
    • 0016275313 scopus 로고
    • Glutathione-S-transferases: The first enzymatic step in mercapturic acid formation
    • Habig WH, Pabst MJ, Jakoby WB (1974). Glutathione-S-transferases: The first enzymatic step in mercapturic acid formation. J Biol Chem 249: 7130-7139.
    • (1974) J Biol Chem , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 20
    • 0021905430 scopus 로고
    • Acute renal failure and glucosuria induced by ferric nitrilotriacetate in rats
    • Hamazaki S, Okada S, Ebina Y, Midorikawa O (1985). Acute renal failure and glucosuria induced by ferric nitrilotriacetate in rats. Toxicol Appl Pharmacol 77: 267-274.
    • (1985) Toxicol Appl Pharmacol , vol.77 , pp. 267-274
    • Hamazaki, S.1    Okada, S.2    Ebina, Y.3    Midorikawa, O.4
  • 21
    • 0024383018 scopus 로고
    • Oxygen reduction and lipid peroxidation by iron chelates with special reference to ferric nitrilotriacetate
    • Hamazaki S, Okada S, Li JL (1989). Oxygen reduction and lipid peroxidation by iron chelates with special reference to ferric nitrilotriacetate. Arch Biochem Biophys 272: 10-17.
    • (1989) Arch Biochem Biophys , vol.272 , pp. 10-17
    • Hamazaki, S.1    Okada, S.2    Li, J.L.3
  • 22
    • 0029100394 scopus 로고
    • Nigella saliva: Effect on human lymphocytes and polymorphonuclear leukocyte phagocytic activity
    • Haq A, Abdullatif M (1995). Nigella saliva: Effect on human lymphocytes and polymorphonuclear leukocyte phagocytic activity. Immunopharmacology 30: 147-155.
    • (1995) Immunopharmacology , vol.30 , pp. 147-155
    • Haq, A.1    Abdullatif, M.2
  • 23
    • 0000100285 scopus 로고
    • Endogenous creatinine in serum and urine
    • Hare RS (1950). Endogenous creatinine in serum and urine. Proc Soc Exp Biol Med 74: 148.
    • (1950) Proc Soc Exp Biol Med , vol.74 , pp. 148
    • Hare, R.S.1
  • 24
    • 0028852880 scopus 로고
    • Fixed oil of Nigella saliva and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation
    • Houghton PJ, Zarka R, Delas HB, Hoult JR (1995). Fixed oil of Nigella saliva and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. Planta Med 61: 33-36.
    • (1995) Planta Med , vol.61 , pp. 33-36
    • Houghton, P.J.1    Zarka, R.2    Delas, H.B.3    Hoult, J.R.4
  • 25
    • 0016151122 scopus 로고
    • Bromobenzene induced liver necrosis: Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite
    • Jollow DJ, Mitchell JR, Zampaglione N, Gillette JR (1974). Bromobenzene induced liver necrosis: Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite. Pharmacology 11: 151.
    • (1974) Pharmacology , vol.11 , pp. 151
    • Jollow, D.J.1    Mitchell, J.R.2    Zampaglione, N.3    Gillette, J.R.4
  • 26
    • 0004214775 scopus 로고
    • USA: The Bobber Merill Company Inc
    • Kanter MW (1975). Clinical Chemistry. USA: The Bobber Merill Company Inc, pp. 80.
    • (1975) Clinical Chemistry , pp. 80
    • Kanter, M.W.1
  • 28
    • 0033059343 scopus 로고    scopus 로고
    • Chemical composition and medicinal properties of Nigella sativa
    • Khan MA (1999). Chemical composition and medicinal properties of Nigella sativa. Inflammopharmacology 7: 15-35.
    • (1999) Inflammopharmacology , vol.7 , pp. 15-35
    • Khan, M.A.1
  • 29
    • 0034961380 scopus 로고    scopus 로고
    • Tephrosia purpurea ameliorates N-diethylnitrosamine and potassium bromate-mediated renal oxidative stress and toxicity in Wistar rats
    • Khan N, Sharma S, Alam A, Saleem S, Sultana S (2001). Tephrosia purpurea ameliorates N-diethylnitrosamine and potassium bromate-mediated renal oxidative stress and toxicity in Wistar rats. Pharmacol Toxicol 88: 294-299.
    • (2001) Pharmacol Toxicol , vol.88 , pp. 294-299
    • Khan, N.1    Sharma, S.2    Alam, A.3    Saleem, S.4    Sultana, S.5
  • 30
    • 0038633459 scopus 로고    scopus 로고
    • Nigella sativa ameliorates potassium bromate induced early events of carcinogenesis: Diminution of oxidative stress
    • Khan N, Sharma S, Sultana S (2003). Nigella sativa ameliorates potassium bromate induced early events of carcinogenesis: diminution of oxidative stress. Hum Exp Toxicol 22: 193-203.
    • (2003) Hum Exp Toxicol , vol.22 , pp. 193-203
    • Khan, N.1    Sharma, S.2    Sultana, S.3
  • 31
    • 1642567494 scopus 로고    scopus 로고
    • Attenuation of potassium bromate-induced nephrotoxicity by coumarin (1,2-benzopyrone) in Wistar rats: Chemoprevention against free radical-mediated renal oxidative stress and tumor promotion response
    • Khan N, Sharma S, Sultana S (2004). Attenuation of potassium bromate-induced nephrotoxicity by coumarin (1,2-benzopyrone) in Wistar rats: chemoprevention against free radical-mediated renal oxidative stress and tumor promotion response. Redox Rep 9: 19-28.
    • (2004) Redox Rep , vol.9 , pp. 19-28
    • Khan, N.1    Sharma, S.2    Sultana, S.3
  • 32
    • 0025720432 scopus 로고
    • The role of oxidative processes in metal carcinogenesis
    • Klein CB, Frenkel K, Costa M (1991). The role of oxidative processes in metal carcinogenesis. Chem Res Toxicol 4: 592-604.
    • (1991) Chem Res Toxicol , vol.4 , pp. 592-604
    • Klein, C.B.1    Frenkel, K.2    Costa, M.3
  • 34
    • 0021752183 scopus 로고
    • Differential distribution of glutathione and glutathione related enzymes in rabbit kidney
    • Mohandas M, Marshal JJ, Duggin GG, Horvath JS, Tiller D (1984). Differential distribution of glutathione and glutathione related enzymes in rabbit kidney. Cancer Res 44: 5086-5091.
    • (1984) Cancer Res , vol.44 , pp. 5086-5091
    • Mohandas, M.1    Marshal, J.J.2    Duggin, G.G.3    Horvath, J.S.4    Tiller, D.5
  • 35
    • 0033065662 scopus 로고    scopus 로고
    • Thymoquinone protects against carbon tetrachloride hepatotoxicity in mice via an antioxidant mechanism
    • Nagi MN, Alam K, Badary OA, et al. (1999). Thymoquinone protects against carbon tetrachloride hepatotoxicity in mice via an antioxidant mechanism. Biochem Mol Biol Int 47: 153-159.
    • (1999) Biochem Mol Biol Int , vol.47 , pp. 153-159
    • Nagi, M.N.1    Alam, K.2    Badary, O.A.3
  • 36
    • 0031612879 scopus 로고    scopus 로고
    • Herbal medicines in Hawaii from tradition to convention
    • Norton SA (1998). Herbal medicines in Hawaii from tradition to convention. Hawaii Med J 57: 382-386.
    • (1998) Hawaii Med J , vol.57 , pp. 382-386
    • Norton, S.A.1
  • 37
    • 0016804041 scopus 로고
    • Induction of the polyamine biosynthetic enzymes in mouse epidermis by tumor promoting agents
    • O'Brien TG, Simsiman RC, Boutwell RK (1975). Induction of the polyamine biosynthetic enzymes in mouse epidermis by tumor promoting agents. Cancer Res 35: 1662-1670.
    • (1975) Cancer Res , vol.35 , pp. 1662-1670
    • O'Brien, T.G.1    Simsiman, R.C.2    Boutwell, R.K.3
  • 38
    • 0027210123 scopus 로고
    • Glutathione cycle dependency of ferric nitrilotriacetate-induced lipid peroxidation in mouse renal proximal tubules
    • Okada S, Minamiyama Y, Hamazaki S, Toyokuni S, Sotomatsu A (1993). Glutathione cycle dependency of ferric nitrilotriacetate-induced lipid peroxidation in mouse renal proximal tubules. Arch Biochem Biophys 301: 138-142.
    • (1993) Arch Biochem Biophys , vol.301 , pp. 138-142
    • Okada, S.1    Minamiyama, Y.2    Hamazaki, S.3    Toyokuni, S.4    Sotomatsu, A.5
  • 39
    • 0015935386 scopus 로고
    • γ-glutamyl cyclotransferase distribution, isozymic forms and specificity
    • Orlowski M, Meister A (1973). γ-glutamyl cyclotransferase distribution, isozymic forms and specificity. J Biol Chem 248: 2836-2844.
    • (1973) J Biol Chem , vol.248 , pp. 2836-2844
    • Orlowski, M.1    Meister, A.2
  • 40
    • 0029455991 scopus 로고
    • Ornithine decarboxylase as a target for chemoprevention
    • Pegg AE, Shantz LM, Colemn CS (1995). Ornithine decarboxylase as a target for chemoprevention. J Biol Chem 22: 132-138.
    • (1995) J Biol Chem , vol.22 , pp. 132-138
    • Pegg, A.E.1    Shantz, L.M.2    Colemn, C.S.3
  • 41
    • 0019504929 scopus 로고
    • 2 production by chemically elicited peritoneal macrophages-induction by multiple non-phagocytic stimulus
    • 2 production by chemically elicited peritoneal macrophages-induction by multiple non-phagocytic stimulus. Cell Immunol 59: 301-308.
    • (1981) Cell Immunol , vol.59 , pp. 301-308
    • Pick, A.1    Keisari, Y.2
  • 42
    • 0027274815 scopus 로고
    • The molecular biology of carcinogenesis
    • Pitot HC (1993). The molecular biology of carcinogenesis. Cancer 72: 962-970.
    • (1993) Cancer , vol.72 , pp. 962-970
    • Pitot, H.C.1
  • 44
    • 0028271504 scopus 로고
    • Overproduction of ornithine decarboxylase caused by relief of translational repression in neoplastic transformation
    • Shantz LM, Pegg AE (1994). Overproduction of ornithine decarboxylase caused by relief of translational repression in neoplastic transformation. Cancer Res 54: 2313-2316.
    • (1994) Cancer Res , vol.54 , pp. 2313-2316
    • Shantz, L.M.1    Pegg, A.E.2
  • 45
    • 0022809615 scopus 로고
    • Sn 1,2-diacylglycerols mimic the effects of TPA in vivo by inducing biochemical changes associated with tumor promotion in mouse epidermis
    • Smart RC, Huang MT, Conney AH (1986). Sn 1,2-diacylglycerols mimic the effects of TPA in vivo by inducing biochemical changes associated with tumor promotion in mouse epidermis. Carcinogenesis 7: 1865-1870.
    • (1986) Carcinogenesis , vol.7 , pp. 1865-1870
    • Smart, R.C.1    Huang, M.T.2    Conney, A.H.3
  • 46
    • 0032813348 scopus 로고    scopus 로고
    • Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances
    • Surh YJ (1999). Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances. Mutat Res 428: 305-327.
    • (1999) Mutat Res , vol.428 , pp. 305-327
    • Surh, Y.J.1
  • 47
    • 0031908086 scopus 로고    scopus 로고
    • Study of the nutritional value of black cumin seeds (Nigella saliva L)
    • Takruri HRH, Dameh MAF (1998). Study of the nutritional value of black cumin seeds (Nigella saliva L). J Sci Food Agriculture 76: 404-410.
    • (1998) J Sci Food Agriculture , vol.76 , pp. 404-410
    • Takruri, H.R.H.1    Dameh, M.A.F.2
  • 49
    • 0032905653 scopus 로고    scopus 로고
    • Inhibition by D-limonene of gastric carcinogenesis induced by N-methyl-N′-nitro-N-nitrosoguanidine in Wistar rats
    • Uedo N, Tatsuta M, Iishi H, et al. (1999). Inhibition by D-limonene of gastric carcinogenesis induced by N-methyl-N′-nitro-N-nitrosoguanidine in Wistar rats. Cancer Lett 137: 131-136.
    • (1999) Cancer Lett , vol.137 , pp. 131-136
    • Uedo, N.1    Tatsuta, M.2    Iishi, H.3
  • 50
    • 0031878048 scopus 로고    scopus 로고
    • The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella saliva L
    • Worthern DR, Ghosheh OA (1998). The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella saliva L. Anticancer Res 18: 1527-1532.
    • (1998) Anticancer Res , vol.18 , pp. 1527-1532
    • Worthern, D.R.1    Ghosheh, O.A.2
  • 51
    • 0019475281 scopus 로고
    • Cytosolic factors that affect microsomal lipid peroxidation in lung and liver
    • Wright JR, Colby HD, Miles PR (1981). Cytosolic factors that affect microsomal lipid peroxidation in lung and liver. Arch Biochem Biophys 206: 296-304.
    • (1981) Arch Biochem Biophys , vol.206 , pp. 296-304
    • Wright, J.R.1    Colby, H.D.2    Miles, P.R.3
  • 52
    • 50549209939 scopus 로고
    • Exposure and solubilization of hepatic mitochondrial shunt dehydrogenases
    • Zaheer N, Tiwari KK, Krishnan PS (1965). Exposure and solubilization of hepatic mitochondrial shunt dehydrogenases. Arch Biochem Biophys 109: 646-648.
    • (1965) Arch Biochem Biophys , vol.109 , pp. 646-648
    • Zaheer, N.1    Tiwari, K.K.2    Krishnan, P.S.3


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