Functional proteins involved in regulation of intracellular Ca2+ for drug development: Desensitization of N-methyl-D-aspartate receptor channels

Journal of Pharmacological Sciences

Volumn 97, Issue 3, 2005, Pages 348-350

  Nakamichi, Noritaka ^a   Yoneda, Yukio ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Internalization; Intracellular Ca2+; NMDA receptor

Indexed keywords

CALCIUM ION; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

CALCIUM CELL LEVEL; CENTRAL NERVOUS SYSTEM; CHANNEL GATING; CONFERENCE PAPER; ENDOCYTOSIS; INTERNALIZATION; RECEPTOR DOWN REGULATION; SYNAPSE;

EID: 17144396710     PISSN: 13478613     EISSN: None     Source Type: Journal    
DOI: 10.1254/jphs.FMJ04007X4     Document Type: Conference Paper

References (22)

1. i in cultured rat hippocampal neurons following exposure to N-methyl-D-aspartate. J Physiol (Lond). 1992;448:655-676.
2. Hirai T, Nakamichi N, Yoneda Y. Activator protein-1 complex expressed by magnetism in cultured rat hippocampal neurons. Biochem Biophys Res Commun. 2002;292:200-207.
3. 2+ increases elicited by N-methyl-D-aspartate in immature and mature cultured cortical neurons. J Neurosci Res. 2002;67:275-283.
4. Scheetz AJ, Constantine-Paton M. Modulation of NMDA receptor function: implications for vertebrate neural development. FASEB J. 1994;8:745-752.
5. Collingridge GL, Bliss TV. Memories of NMDA receptors and LTP. Trends Neurosci. 1995;18:54-56.
6. Choi DW. Glutamate receptors and the induction of excitotoxic neuronal death. Prog Brain Res. 1994;100:47-51.
7. Xia Y, Ragan RE, Seah EE, Michaelis ML, Michaelis EK. Developmental expression of N-methyl-D-aspartate (NMDA)-induced neurotoxicity, NMDA receptor function, and the NMDA R1 and glutamate-binding protein subunits in cerebellar granule cells in primary cultures. Neurochem Res. 1995;20:617-629.
8. Hollmann M, Heinemann S. Cloned glutamate receptors. Annu Rev Neurosci. 1994;17:31-108.
9. Yoneda Y, Kuramoto N, Kitayama T, Hinoi E. Consolidation of transient ionotropic glutamate signals through nuclear transcription factors in the brain. Prog Neurobiol. 2001;63:697-719.
10. Chatterton JE, Awobuluyi M, Premkumar LS, Takahashi H, Talantova M, Shin Y, et al. Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits. Nature. 2002;415:793-798.
11. Li Y, Erzurumlu RS, Chen C, Jhaveri S, Tonegawa S. Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice. Cell. 1994;76:427-437.
12. Forrest D, Yuzaki M, Soares HD, Ng L, Luk DC, Sheng M, et al. Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death. Neuron. 1994;13:325-338.
13. Carroll RC, Zukin RS. NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity. Trends Neurosci. 2002;25:571-577.
14. 2+ permeability of AMPA-type glutamate receptor channels in neocortical neurons caused by differential GluR-B subunit expression. Neuron. 1994;12:1281-1289.
15. Watanabe M, Inoue Y, Sakimura K, Mishina M. Developmental changes in distribution of NMDA receptor channel subunit mRNAs. Neuroreport. 1992;3:1138-1140.
16. Williams K, Russell SL, Shen YM, Molinoff PB. Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro. Neuron. 1993;10:267-278.
17. Man HY, Lin JW, Ju WH, Ahmadian G, Liu L, Becker LE, et al. Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization. Neuron. 2000;25:649-662.
18. Roche KW, Standley S, McCallum J, Dune Ly C, Ehlers MD, Wenthold RJ. Molecular determinants of NMDA receptor internalization. Nat Neurosci. 2001;4:794-802.
19. Nong Y, Huang YQ, Ju W, Kalia LV, Ahmadian G, Wang YT, et al. Glycine binding primes NMDA receptor internalization. Nature. 2003;422:302-307.
20. 2+ influx through N-methyl-D-aspartate receptor channels in immature cultured rat cortical neurons. J Neurochem. 2002;83:1-11.
21. Vissel B, Krupp JJ, Heinemann SF, Westbrook GL. A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion flux. Nat Neurosci. 2001;4:587-596.
22. Nong Y, Huang YQ, Salter MW. NMDA receptors are movin' in. Curr Opin Neurobiol. 2004;14:353-361.