3-Substituted imidazo[1,2-d][1,2,4]-thiadiazoles: A novel class of factor XIIIa inhibitors

Journal of Medicinal Chemistry

Volumn 48, Issue 7, 2005, Pages 2266-2269

  Leung Toung, Regis ^a   Tam, Tim F ^a   Wodzinska, Jolanta M ^a   Zhao, Yanqing ^a   Lowrie, Jayme ^a   Simpson, Craig D ^a   Karimian, Khashayar ^a   Spino, Michael ^a  

^a Apotex Research Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALUTACENOIC ACID A; BLOOD CLOTTING FACTOR 13A; BLOOD CLOTTING FACTOR 13A INHIBITOR; BLOOD CLOTTING INHIBITOR; CERULENIN; FIBRIN; POLYPEPTIDE; THIADIAZOLE DERIVATIVE; TISSUE PLASMINOGEN ACTIVATOR; TRIDEGIN; UNCLASSIFIED DRUG; ZG 1400;

ARTICLE; ATHEROSCLEROSIS; BLOOD CLOTTING; BLOOD CLOTTING TIME; CONTROLLED STUDY; CROSS LINKING; DRUG STRUCTURE; FIBRIN CLOT; FIBRINOLYSIS; HUMAN; ISCHEMIC HEART DISEASE; NONHUMAN; PHARMACOPHORE; POLYMERIZATION; THROMBOSIS;

ANIMALS; FACTOR XIII; FIBRINOLYTIC AGENTS; GUINEA PIGS; HUMANS; IMIDAZOLES; KINETICS; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZOLES;

EID: 17144386944     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049221w     Document Type: Article

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