Expression of apoptotic and cell proliferation regulatory proteins in actinic cheilitis

Journal of Oral Pathology and Medicine

Volumn 34, Issue 5, 2005, Pages 257-262

  Martínez, Alejandra ^a,b   Brethauer, U ^a   Rojas, I G ^a   Spencer, M ^a   Mucientes, F ^a   Borlando, J ^a   Rudolph, M I ^a  

^a UNIVERSITY OF CONCEPCIÓN   (Chile)

^b NONE   (Chile)

Author keywords

Actinic cheilitis; Bax; Bcl 2; Ki 67; p53

Indexed keywords

DNA; KI 67 ANTIGEN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REGULATOR PROTEIN;

ACTINIC CHEILITIS; ADULT; AGED; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CHEILITIS; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DAMAGE; EPITHELIUM CELL; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIP CARCINOMA; LOWER LIP; MALE; PRECANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; ULTRAVIOLET RADIATION;

ADULT; AGED; ANALYSIS OF VARIANCE; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL PROLIFERATION; CHEILITIS; FEMALE; HUMANS; KI-67 ANTIGEN; LIP; MALE; MIDDLE AGED; MOUTH MUCOSA; PROTO-ONCOGENE PROTEINS C-BCL-2; STATISTICS, NONPARAMETRIC; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 17144374456     PISSN: 09042512     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2004.00299.x     Document Type: Article

References (37)

1. Main JH, Pavone M. Actinic cheilitis and carcinoma of the lip. J Can Dent Assoc 1994; 60: 113-6.
2. Kaugars GE, Pillion T, Svirsky JA, Page DG, Burns JC, Abbey LM. Actinic cheilitis: a review of 152 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999; 88: 181-6.
3. Santorres M, Gargallo J, Gay C. Tratamiento quirúrgico de la queilitis actínica. Med Oral 2001; 6: 205-17.
4. Girard KR, Hoffmann BL. Actinic cheilitis. Oral Surg 1980; 50: 21-4.
5. Warnakulasuriya KAAS, Johnson NW. Association of overexpression of p53 oncoprotein with the state of cell proliferation in oral carcinoma. J Oral Pathol Med 1994; 23: 246-50.
6. Loro LL, Vintermyr OK, Johannnessen AC. Cell death regulation in oral squamous cell carcinoma: methodological considerations and clinical significance. J Oral Pathol Med 1999; 32: 125-38.
7. Souza PEA, Paim JFO, Carvalhais JN, Gomez RS. Immunohistochemical expression of p53, MDM2, Ki-67 and PCNA in central giant cell granuloma and giant cell tumor. J Oral Pathol Med 1999; 28: 54-8.
8. Yanamoto S, Kawasaki G, Yoshitomi I, Mizuno A. p53, mdm2, and p21 expression in oral squamous cell carcinomas: relationship with clinicopathologic factors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002; 94: 593-600.
9. Berhane T, Halliday GM, Cooke B, Barnetson RS. Inflammation is associated with progression of actinic keratoses to squamous cell carcinomas in humans. Br J Dermatol 2002; 146: 810-5.
10. Einspahr JG, Alberts DS, Warneke JA, et al. Relationship of p53 mutations to epidermal cell proliferation and apoptosis in human UV-induced skin carcinogenesis. Neoplasia 1999; 1: 468-75.
11. Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med 1997; 3: 614-20.
12. Korsmeyer SJ. Regulation of cell death. Trends Genet 1995; 11: 101-5.
13. Chiou SK, Rao L, White E. Bcl-2 blocks p53-dependent apoptosis. Mol Cell Biol 1994; 14: 2556-63.
14. Raybaud H, Odin G, Fafet A, Santini J, Monteil RA. Anomalies géniques dans les carcinomes épidermoïdes des voies aérodigestives supérieures: analyse de la littérature internationale. Pathol Biol (Paris) 2003; 51: 176-84.
15. Jordan RC, Catzavelo GC, Barrett AW, Speight PM. Differential expression of bcl-2 and bax in squamous cell carcinomas of the oral cavity. Eur J Cancer B Oral Oncol 1996; 32: 394-400.
16. Saito K, Mori S, Tanda N, Sakamoto S. Expresssion of p53 protein and Ki- 67 antigen in gingival hyperplasia induced nifedipine and phenytoin. J Periodontol 1999; 70: 581-6,
17. Kurokawa H, Matsumoto S, Murata T, et al. Immunohistochemical study of syndecan-1 down-regulation and the expression of the p53 protein or Ki-67 antigen in oral leukoplakia with or without epithelial dysplasia. J Oral Pathol Med 2003; 32: 513-21.
18. Tabor MP, Braakhuis BJ, van der Wal JE, et al. Comparative molecular and histological grading of epithelial dysplasia of the oral cavity and the oropharynx. J Pathol 2003; 199: 354-60.
19. Slootweg PJ, Koole R, Hordijk GJ. The presence of p53 protein in relation to Ki-67 as cellular proliferation marker in head and neck squamous cell carcinoma and adjacent dysplastic mucosa. Eur J Cancer B Oral Oncol 1994; 30B: 138-41.
20. Kripke ML. Immunologic mechanisms in UV radiation carcinogenesis. Adv Cancer Res 1981; 34: 69-106.
21. Streilein JW, Taylor JR, Vincek V, et al. Immune surveillance and sunlight-induced skin cancer. Immunol Today 1994; 15: 174-9.
22. Tron VA, Trotter MJ, Tang L, et al. p53-regulated apoptosis is differentiation dependent in ultraviolet B-irradiated mouse keratinocytes. Am J Pathol 1998; 153: 579-85.
23. Rudolph P, Tronnier M, Menzel R, Moller M, Parwaresch R. Enhanced expression of Ki-67, topoisomerase IIalpha, PCNA, p53 and p21 WAF1/Cip1 reflecting proliferation and repair activity in UV-irradiated melanocytic nevi. Hum Pathol 1998; 29: 1480-7.
24. Murphy M, Mabruk MJ, Lenane P, et al. Comparison of the expression of p53, p21, bax and the induction of apoptosis between patients with basal cell carcinomas and normal controls in response to ultraviolet irradiation. J Clin Pathol 2002; 55: 829-33.
25. Murphy M, Mabruk MJ, Lenane P, et al. The expression of p53, p21, bax and induction of apoptosis in normal volunteers in response to different doses of ultraviolet radiation. Br J Dermatol 2002; 147: 110-7.
26. Lee JK, Kim JH, Nam KT, Lee SH. Molecular events associated with apoptosis and proliferation induced by ultraviolet-B radiation in the skin of hairless mice. J Dermatol Sci 2003; 32: 171-9.
27. Feinmesser M, Tsabari C, Fichman S, Hodak E, Sulkes J, Okon E. Differential expression of proliferation- and apoptosis-related markers in lentigo maligna and solar keratosis keratinocytes. Am J Dermatopathol 2003; 25: 300-7.
28. Ouhtit A, Muller HK, Davis DW, Ullrich SE, McConkey D, Ananthaswamy HN. Temporal events in skin injury and the early adaptive responses in ultraviolet-irradiated mouse skin. Am J Pathol 2000; 156: 201-7.
29. Edström DW, Porwit A, Ros AM. Effects on human skin of repetitive ultraviolet-A1 (UVA1) irradiation and visible light. Photodermatol Photoimmunol Photomed 2001; 17: 66-70.
30. Kulms D, Schwarz T. Molecular mechanisms of UV-induced apoptosis. Photodermatol Photoimmunol Photomed 2000; 16: 195-201.
31. Nylander K, Dabelsteen E, Hall PA. The p53 molecule and its prognostic role in squamous cell carcinomas of the head and neck. J Oral Pathol Med 2000; 29: 413-25.
32. Crosthwaite N, Teale D, Franklin C, Foster GA, Stringer BM. p53 protein expression in malignant, pre-malignant and non-malignant lesions on the lip. J Clin Pathol 1996; 49: 648-53.
33. Fabbrocini G, Russo N, Pagliuca MC, et al. p53, cyclin-D1, PCNA, AgNOR expression in squamous cell cancer of the lip: a multicenter study. Photodermatol Photoimmunol Photomed 2000; 16: 172-7.
34. Isoherranen K, Sauroja I, Jansen C, Punnonen K. UV irradiation induces downregulation of bcl-2 expression in vitro and in vivo. Arch Dermatol Res 1999; 291: 212-6.
35. Washio F, Ueda M, Ito A, Ichihashi M. Higher susceptibility to apoptosis following ultraviolet B irradiation of xeroderma pigmentosum fibroblasts is accompanied by upregulation of p53 and downregulation of bcl-2. Br J Dermatol 1999; 140: 1031-7.
36. Gerdes J, Lemke M, Baisch H, Wacker HH, Schwab U, Stein H. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 1944; 133: 1710-5.
37. Gonzalez-Moles MA, Ruiz-Avila I, Rodriguez-Archilla A, Martinez-Lara I. Suprabasal expression of Ki-67 antigen as a marker for the presence and severity of oral epithelial dysplasia. Head Neck 2000; 22: 658-61.