Bacteraemia prediction in emergency medical admissions: Role of C reactive protein

Journal of Clinical Pathology

Volumn 58, Issue 4, 2005, Pages 352-356

  Wyllie, D H ^a,c   Bowler, I C J W ^c   Peto, T E A ^b  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN;

ACUTE DISEASE; ADULT; AGED; ARTICLE; BACTEREMIA; BLOOD CULTURE; COHORT ANALYSIS; EMERGENCY HEALTH SERVICE; HOSPITAL ADMISSION; HUMAN; HUMAN CELL; INFECTION RISK; LYMPHOCYTE COUNT; LYMPHOCYTOPENIA; MAJOR CLINICAL STUDY; MEASUREMENT; NEUTROPHIL; NEUTROPHILIA; NONHUMAN; OUTCOMES RESEARCH; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TECHNIQUE; UNITED KINGDOM; VALIDATION PROCESS;

ACUTE DISEASE; ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; BACTEREMIA; C-REACTIVE PROTEIN; COHORT STUDIES; EMERGENCIES; HUMANS; LEUKOCYTE COUNT; LIKELIHOOD FUNCTIONS; LYMPHOCYTE COUNT; MIDDLE AGED; NEUTROPHILS; RISK ASSESSMENT;

EID: 17144368802     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.2004.022293     Document Type: Article

References (29)

1. Mylotte JM, Kahler L, McCann C. Community-acquired bacteremia at a teaching versus a nonteaching hospital: impact of acute severity of illness on 30-day mortality. Am J Infect Control 2001;29:13-19.
2. Bates DW, Pruess KE, Lee TH. How bad are bacteremia and sepsis? Outcomes in a cohort with suspected bacteremia. Arch Intern Med 1995;155:593-8.
3. Hanon FX, Monnet DL, Sorensen TL, et al. Survival of patients with bacteraemia in relation to initial empirical antimicrobial treatment. Scand J Infect Dis 2002;34:520-8.
4. Valles J, Rello J, Ochagavia A, et al. Community-acquired bloodstream infection in critically ill adult patients: impact of shock and inappropriate antibiotic therapy on survival. Chest 2003;123:1615-24.
5. Le Tulzo Y, Pangault C, Gacouin A, et al. Early circulating lymphocyte apoptosis in human septic shock is associated with poor outcome. Shock 2002;18:487-94.
6. Hotchkiss RS, Tinsley KW, Swanson PE, et al. Prevention of lymphocyte cell death in sepsis improves survival in mice. Proc Natl Acad Sci U S A 1999;96:14541-6.
7. Hotchkiss RS, Chang KC, Swanson PE, et al. Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte. Nat Immunol 2000;1:490-501.
8. Bone RC, Sibbald WJ, Sprung CL. The ACCP-SCCM consensus conference on sepsis and organ failure. Chest 1992;101:1481-3.
9. Shapiro NI, Wolfe RE, Wright S, et al. Who needs a blood culture? A prospectively derived and validated clinical prediction rule. Acad Emerg Med 2003;10:435-6.
10. Wyllie DH, Peto TEA, Bowler ICJ. Relation between lymphopenia and bacteraemia in UK adults with medical emergencies. J Clin Pathol 2004;57:950-5.
11. Chirouze C, Schuhmacher H, Rabaud C, et al. Low serum procalcitonin level accurately predicts the absence of bacteremia in adult patients with acute fever. Clin Infect Dis 2002;35:156-61.
12. Rintala EM, Aittoniemi J, Laine S, et al. Early identification of bacteremia by biochemical markers of systemic inflammation. Scand J Clin Lab Invest 2001;61:523-30.
13. McCabe RE, Remington JS. C-reactive protein in patients with bacteremia. J Clin Microbiol 1984;20:317-19.
14. Dryden MS. C-reactive protein concentration in suspected bacteraemia. J Clin Pathol 1986;39:1363-4.
15. Byl B, Deviere J, Saint-Hubert F, et al. Evaluation of tumor necrosis factor-alpha, interleukin-6 and C-reactive protein plasma levels as predictors of bacteremia in patients presenting signs of sepsis without shock. Clin Microbiol Infect 1997;3:306-16.
16. Chassagne P, Perol MB, Doucet J, et al. Is presentation of bacteremia in the elderly the same as in younger patients? Am J Med 1996;100:65-70.
17. Jaeschke R, Guyatt GH, Sackett DL. Users' guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group. JAMA 1994;271:703-7.
18. van Dissel JT, van Langevelde P, Westendorp RG, et al. Anti-inflammatory cytokine profile and mortality in febrile patients. Lancet 1998;351:950-3.
19. van Langevelde P, Joop K, van Loon J, et al. Endotoxin, cytokines, and procalcitonin in febrile patients admitted to the hospital: identification of subjects at high risk of mortality. Clin Infect Dis 2000;31:1343-8.
20. Leaver HA, Yap PL, Rogers P, et al. Peroxides in human leucocytes in acute septic shock: a preliminary study of acute phase changes and mortality. Eur J Clin Invest 1995;25:777-83.
21. Lobo SM, Lobo FR, Bota DP, et al. C-reactive protein levels correlate with mortality and organ failure in critically ill patients. Chest 2003;123:2043-9.
22. Reny JL, Vuagnat A, Ract C, et al. Diagnosis and follow-up of infections in intensive care patients: value of C-reactive protein compared with other clinical and biological variables. Crit Care Med 2002;30:529-35.
23. Chan YL, Tseng CP, Tsay PK, et al. Procalcitonin as a marker of bacterial infection in the emergency department: an observational study. Crit Care 2004;8:R12-20.
24. Hausfater P, Garric S, Ayed SB, et al. Usefulness of procalcitonin as a marker of systemic infection in emergency department patients: a prospective study. Clin Infect Dis 2002;34:895-901.
25. Guven H, Altintop L, Baydin A, et al. Diagnostic value of procalcitonin levels as an early indicator of sepsis. Am J Emerg Med 2002;20:202-6.
26. Hedlund J, Hansson LO. Procalcitonin and C-reactive protein levels in community-acquired pneumonia: correlation with etiology and prognosis. Infection 2000;28:68-73.
27. Luzzani A, Polati E, Dorizzi R, et al. Comparison of procalcitonin and C-reactive protein as markers of sepsis. Crit Care Med 2003;31:1737-41.
28. Brunkhorst FM, Clark AL, Farycki ZF, et al. Pyrexia, procalcitonin, immune activation and survival in cardiogenic shock: the potential importance of bacterial translocation. Int J Cardiol 1999;72:3-10.
29. Tugrul S, Esen F, Celebi S, et al. Reliability of procalcitonin as a severity marker in critically ill patients with inflammatory response. Anaesth Intensive Care 2002;30:747-54.