Effects of glutamine supplementation on splenocyte cytokine mRNA expression in rats with septic peritonitis

World Journal of Gastroenterology

Volumn 11, Issue 12, 2005, Pages 1742-1746

  Yeh, Sung Ling ^a   Lai, Yu Ni ^a   Shang, Huey Fang ^a   Lin, Ming Tsan ^b   Chiu, Wan Chun ^a   Chen, Wei Jao ^b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Glutamine; Total parenteral nutrition

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CYTOKINE; GAMMA INTERFERON; GLUTAMINE; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; MESSENGER RNA; NITROGEN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG MECHANISM; FOOD COMPOSITION; MALE; NONHUMAN; PERITONITIS; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SEPSIS; SPLEEN; SPLEEN CELL; T LYMPHOCYTE; TOTAL PARENTERAL NUTRITION;

EID: 17144364669     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i12.1742     Document Type: Article

References (22)

1. Souba WW, Herskowitz K, Klimberg VS, Salloum RM, Plumley DA, Flynn TC, Copeland EM III. The effects of sepsis and endotoxemia on gut glutamine metabolism. Ann Surg 1990; 211: 543-549
2. Ertel W, Morrison MH, Wang P, Zheng F, Ayala A, Chaudry IH. The complex of cytokines in sepsis. Ann Surg 1991; 214: 141-148
3. Fong Y, Moldawer LL, Shires GT, Lowry SF. The biologic characteristics of cytokines and their implication in surgical injury. Surgery 1990; 170: 363-377
4. Blaschke V, Reich K, Blaschke S, Zipprich S, Neumann C. Rapid quantitation of proinflammatory and chemoattractant cytokine expression in small tissue samples and monocyte-derived dendritic cells: Validation of a new-real-time RT-PCR technology. J Immunol Meth 2000; 246: 79-90
5. Navaratnam RL, Morris SE, Traber DL, Flynn J, Woodson L, Linare SH, Herndon DN. Endotoxin (LPS) increases mesenteric vascular resistance (MVR) and bacterial translocation (BT). J Trauma 1990; 30: 1104-1113
6. Gardiner K, Barbul A. Intestinal amino acid absorption during sepsis. J Parenter Enter Nutr 1993; 17: 277-283
7. Gardiner KR, Gardiner RE, Barbul A. Reduced intestinal absorption of arginine during sepsis. Crit Care Med 1995; 23: 1227-1232
8. Okada Y, Papp E, Klein NJ, Pierro A. Total parenteral nutrition directly impairs cytokine production after bacterial challenge. J Pediatr Surg 1999; 34: 277-280
9. Willmore DW. The effects of glutamine supplementation in patients following elective surgery and accidental injury. J Nutr 2001; 131: 2543S-2549S
10. Stehle P, Zander J, Mertes N, Albers S, Puchestein C, Lawin P, Furst P. Effect of parenteral glutamine peptide supplements on muscle glutamine loss and nitrogen balance after major surgery. Lancet 1989; 1: 231-233
11. van der Hulst RR, van Kreel BK, von Meyenfeldt MF, Brummer RJ, Arends JW, Dentz NE, Soeters PB. Glutamine and the preservation of gut integrity. Lancet 1993; 341: 1363-1365
12. Calder PC. Glutamine and the immune system. Clin Nutr 1994; 13: 2-5
13. Lai YN, Yeh SL, Lin MT, Shang HF, Yeh CL, Chen WJ. Glutamine supplementation enhances mucosal immunity in rats with gut-derived sepsis. Nutrition 2004; 20: 286-291
14. Yeh SL, Lai YN, Shang HF, Lin MT, Chen WJ. Effects of glutamine supplementation on innate immune response in rats with gut-derived sepsis. Br J Nutr 2004; 91: 1-8
15. Wu RQ, Xu YX, Song XH, Chen LJ, Meng XJ. Relationship between cytokine mRNA expression and organ damage following cecal ligation and puncture. World J Gastroenterol 2002; 8: 131-134
16. Foex BA, Shelly MP. The cytokine response to critical illness. J Accid Emerg Med 1996; 13: 154-162
17. Wichterman KA, Baue AE, Chaudry IH. Sepsis and septic shock-a review of laboratory models and a proposal. J Surg Res 1980; 29: 189-201
18. Yeh SL, Yeh CL, Lin MT, Lo PN, Chen WJ. Effects of glutamine-supplemented total parenteral nutrition on cytokine production and T cell population in septic rats. J Parenter Enter Nutr 2001; 25: 269-274
19. Cruickshank AM, Fraser WD, Burns HJG, Van Dame J, Shenkin A. Response of serum interleukin-6 in patients undergoing elective surgery with varying intensities. Clin Sci 1990; 79: 161-165
20. DiPiro JT. Cytokine networks with infection: mycobacterial infectons, leishmaniasis, human immunodeficiency virus infection, and sepsis. Pharmacotherapy 1997; 17: 205-223
21. Fukatsu K, Kudsk KA, Zarzarur BL, Wu Y, Hanna MK, DeWitt RC. TPN decreses IL-4 and IL-10 mRNA expression in lipopolysaccharide-stimulated intestinal laminar propria cells but glutamine supplementation preserves the expression. Shock 2001; 15: 318-322
22. Moncada S, Higgs EA. The L-arginine-nitric oxide pathway. New Engl J Med 1993; 329: 2002-2012