Characterization of M cell formation and associated mononuclear cells during indomethacin-induced intestinal inflammation

Clinical and Experimental Immunology

Volumn 136, Issue 2, 2004, Pages 232-238

  Lugering A ^a   Floer, M ^b   Lugering N ^b   Cichon, C ^a   Schmidt, M A ^a   Domschke, W ^b   Kucharzik, T ^b  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b NONE

Author keywords

Follicle associated epithelium; Ileitis; Indomethacin; Intestinal M cells; Peyer's patch

Indexed keywords

CD11B ANTIGEN; CD4 ANTIGEN; INDOMETACIN; INTERLEUKIN 2 RECEPTOR; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; DERIVATIZATION; DISEASE ASSOCIATION; DRUG INDUCED DISEASE; ELECTRON MICROSCOPY; ENTERITIS; EPITHELIUM CELL; FEMALE; IN SITU HYBRIDIZATION; INJECTION; LYMPHOCYTE; MICROENVIRONMENT; MONONUCLEAR CELL; MOUSE; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROVOCATION TEST;

ANIMALS; FEMALE; ILEITIS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INDOMETHACIN; INTERLEUKIN-4; INTESTINAL MUCOSA; LEUKOCYTES, MONONUCLEAR; MICROSCOPY, IMMUNOELECTRON; MODELS, ANIMAL; PEYER'S PATCHES; RATS; RATS, WISTAR; RNA, MESSENGER;

EID: 17044451133     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2004.02438.x     Document Type: Article

References (32)

1. Neutra MR, Pringault E, Kraehenbuhl JP. Antigen sampling across epithelial barriers and induction of mucosal immune responses. Annu Rev Immunol 1996; 14:275-300.
2. Neutra MR. Current concepts in mucosal immunity. V. Role of M cells in transepithelial transport of antigens and pathogens to the mucosal immune system. Am J Physiol 1998; 274:G785-91.
3. Wolf JL, Bye WA. The membranous epithelial (M) cell and the mucosal immune system. Annu Rev Med 1984; 35:95-112.
4. Owen RL, Jones AL. Epithelial cell specialization within human Peyer's patches: an ultrastructural study of intestinal lymphoid follicles. Gastroenterology 1974; 66:189-203.
5. Trier JS. Structure and function of intestinal M cells. Gastroenterol Clin North Am 1991; 20:531-47.
6. Gebert A, Posselt W. Glycoconjugate expression defines the origin and differentiation pathway of intestinal M-cells. J Histochem Cytochem 1997; 45:1341-50.
7. Giannasca PJ, Giannasca KT, Falk P et al. Regional differences in glycoconjugates of intestinal M cells in mice: potential targets for mucosal vaccines. Am J Physiol 1994; 267:G1108-21.
8. Kerneis S, Bogdanova A, Kraehenbuhl JP et al. Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria. Science 1997; 277:949-52.
9. Kerneis S, Caliot E, Stubbe H et al. Molecular studies of the intestinal mucosal barrier physiopathology using cocultures of epithelial and immune cells: a technical update. Microbes Infect 2000; 2:1119-24.
10. Borghesi C, Taussig MJ, Nicoletti C. Rapid appearance of M cells after microbial challenge is restricted at the periphery of the follicle-associated epithelium of Peyer's patch. Lab Invest 1999; 79:1393-401.
11. Kucharzik T, Lugering A, Lugering N et al. Characterization of M cell development during indomethacin-induced ileitis in rats. Aliment Pharmacol Ther 2000; 14:247-56.
12. Rautenberg K, Cichon C, Heyer G et al. Immunocytochemical characterization of the follicle-associated epithelium of Peyer's patches: anticytokeratin 8 antibody (clone 4.1.18) as a molecular marker for rat M cells. Eur J Cell Biol 1996; 71:363-70.
13. Owen RL, Bhalla DK. Cytochemical analysis of alkaline phosphatase and esterase activities and of lectin-binding and anionic sites in rat and mouse Peyer's patch M cells. Am J Anat 1983; 168:199-212.
14. Smith MW, Peacock MA. 'M' cell distribution in follicle-associated epithelium of mouse Peyer's patch. Am J Anat 1980; 159:167-75.
15. Cuvelier CA, Quatacker J, Mielants H et al. M-cells are damaged and increased in number in inflamed human ileal mucosa. Histopathology 1994; 24:417-26.
16. Fujimura Y, Hosobe M, Kihara T. Ultrastructural study of M cells from colonic lymphoid nodules obtained by colonoscopic biopsy. Dig Dis Sci 1992; 37:1089-98.
17. Anthony A, Pounder RE, Dhillon AP et al. Similarities between ileal Crohn's disease and indomethacin experimental jejunal ulcers in the rat. Aliment Pharmacol Ther 2000; 14:241-5.
18. Satoh H, Guth PH, Grossman MI. Role of bacteria in gastric ulceration produced by indomethacin in the rat cytoprotective action of antibiotics. Gastroenterology 1983; 84:483-9.
19. Kent TH, Cardelli RM, Stamler FW. Small intestinal ulcers and intestinal flora in rats given indomethacin. Am J Pathol 1969; 54:237-49.
20. Borghesi C, Regoli M, Bertelli E et al. Modifications of the follicle-associated epithelium by short-term exposure to a non-intestinal bacterium. J Pathol 1996; 180:326-32.
21. Farstad IN, Halstensen TS, Fausa O et al. Heterogeneity of M-cell-associated B and T cells in human Peyer's patches. Immunology 1994; 83:457-64.
22. Yamanaka T, Straumfors A, Morton H et al. M cell pockets of human Peyer's patches are specialized extensions of germinal centers. Eur J Immunol 2001; 31:107-17.
23. Iwasaki A, Kelsall BL. Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3alpha, MIP-3beta, and secondary lymphoid organ chemokine. J Exp Med 2000; 191:1381-94.
24. Kucharzik T, Hudson JT III, Waikel RL et al. CCR6 expression distinguishes mouse myeloid and lymphoid dendritic cell subsets: demonstration using a CCR6 EGFP knock-in mouse. Eur J Immunol 2002; 32:104-12.
25. + dendritic cells. J Immunol 2003; 171:2797-803.
26. Jump RL, Levine AD. Murine Peyer's patches favor development of an IL-10-secreting, regulatory T cell population. J Immunol 2002; 168:6113-9.
27. Nicoletti C. Unsolved mysteries of intestinal M cells. Gut 2000; 47:735-9.
28. Savidge TC, Smith MW, James PS. A confocal microscopical analysis of Peyer's patch membranous (M) cell and lymphocyte interactions in the scid mouse. Adv Exp Med Biol 1995; 371A:243-5.
29. Inobe J, Slavin AJ, Komagata Y et al. IL-4 is a differentiation factor for transforming growth factor-beta secreting Th3 cells and oral administration of IL-4 enhances oral tolerance in experimental allergic encephalomyelitis. Eur J Immunol 1998; 28:2780-90.
30. Colgan SP, Resnick MB, Parkos CA et al. IL-4 directly modulates function of a model human intestinal epithelium. J Immunol 1994; 153:2122-9.
31. Fujimura Y, Kamoi R, Iida M. Pathogenesis of aphthoid ulcers in Crohn's disease, correlative findings by magnifying colonoscopy, electron microscopy, and immunohistochemistry. Gut 1996; 38:724-32.
32. Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 1998; 115:182-205.