Crosslinking renders bacteriophage HK97 capsid maturation irreversible and effects an essential stabilization

EMBO Journal

Volumn 24, Issue 7, 2005, Pages 1352-1363

  Ross, Philip D ^a   Cheng, Naiqian ^b   Conway, James F ^c   Firek, Brian A ^d   Hendrix, Roger W ^d   Duda, Robert L ^d   Steven, Alasdair C ^b,e  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^c INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^d UNIVERSITY OF PITTSBURGH   (United States)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Brownian ratchet; Conformational change; Cryo electron microscopy; Differential scanning calorimetry; Virus assembly

Indexed keywords

ARTICLE; BACTERIOPHAGE; BACTERIOPHAGE HK97; COVALENT BOND; CROSS LINKING; CRYOELECTRON MICROSCOPY; DENATURATION; DIFFERENTIAL SCANNING CALORIMETRY; HEAD II CAPSID; K169Y CAPSID; MOLECULAR STABILITY; MUTANT; NONHUMAN; PH; PRIORITY JOURNAL; PROHEAD II CAPSID; TEMPERATURE DEPENDENCE; THERMOSTABILITY; VIRUS CAPSID; WILD TYPE;

BACTERIOPHAGES; CALORIMETRY, DIFFERENTIAL SCANNING; CAPSID PROTEINS; CRYOELECTRON MICROSCOPY; GENETIC COMPLEMENTATION TEST; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; PROTEIN SUBUNITS; VIRAL CORE PROTEINS; VIRUS ASSEMBLY;

EID: 17044437232     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600613     Document Type: Article

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