What are the links between Epstein-Barr virus, lymphoma, and tumor necrosis factor antagonism in rheumatoid arthritis?

Seminars in Arthritis and Rheumatism

Volumn 34, Issue 5 SUPPL., 2005, Pages 31-33

  Balandraud, Nathalie ^a,b   Roudier, Jean ^a,b   Roudier, Chantal ^a,b  

^a INSERM   (France)

^b HÔPITAL DE LA CONCEPTION   (France)

Author keywords

EBV load; Epstein Barr virus; Lymphoma; Methotrexate; Rheumatoid arthritis; Tumor necrosis factor inhibitors

Indexed keywords

ADALIMUMAB; ETANERCEPT; IMMUNOSUPPRESSIVE AGENT; INFLIXIMAB; METHOTREXATE;

CANCER INCIDENCE; CANCER PREVENTION; CANCER RISK; CLINICAL TRIAL; CONFERENCE PAPER; DISEASE ACTIVITY; EPSTEIN BARR VIRUS; HODGKIN DISEASE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOSUPPRESSIVE TREATMENT; INFECTION SENSITIVITY; LYMPHOMA; NONHODGKIN LYMPHOMA; PATIENT MONITORING; PREDICTION; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; VIRUS IMMUNITY; VIRUS INFECTION; VIRUS LOAD;

EID: 17044398108     PISSN: 00490172     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semarthrit.2005.01.008     Document Type: Conference Paper

References (16)

1. M. Alspaugh, G. Henle, E. Lennette Elevated levels of antibodies to Epstein Barr virus antigens in sera and synovial fluids of patients with rheumatoid arthritis J Clin Invest 67 1981 1134 1140
2. E. Toussirot, I. Auger, C. Roudier HLA-DR polymorphism influences T cell precursor frequencies to EBV gp110. Implications for the association of HLA-DR antigens with rheumatoid arthritis Tissue Antigens 54 1999 146 152
3. G. Tosato, A. Steinberg, M. Blaese Defective EBV specific suppressor T cell function in rheumatoid arthritis N Engl J Med 305 1981 1238 1243
4. N. Balandraud, J.B. Meynard, I. Auger Epstein Barr virus load in the peripheral blood of patients with rheumatoid arthritis. Accurate quantification using real time PCR Arthritis Rheum 48 2003 1223 1228
5. K. Macsween, D. Crawford Epstein Barr virus--recent advances Lancet Infect Dis 3 2003 131 140
6. A. Swerdlow Epidemiology of Hodgkin's disease and non Hodgkin's lymphoma Eur J Nucl Med Mol Imaging 30 Suppl. 1 2003 S3 S12
7. D. Thorley-Lawson, A. Gross Persistence of the Epstein Barr virus and the origins of associated lymphomas N Engl J Med 350 2004 1328 1337
8. F. Baldanti, P. Grossi, M. Furione High levels of Epstein Barr virus DNA in blood of solid organ transplant recipients and their value in predicting posttransplant lymphoproliferative disorders J Clin Microbiol 38 2000 613 619
9. H. Kimura, M. Morito, Y. Yabuta Quantitative analysis of Epstein Barr virus load by using a real time PCR assay J Clin Microbiol 37 1999 132 136
10. E. Baecklund, C. Sundstrom, A. Ekbom Lymphoma subtypes in patients with rheumatoid arthritis. Increased proportion of diffuse large B cell lymphoma Arthritis Rheum 48 2003 1543 1550
11. E. Baecklund, A. Ekbom, P. Sparen Disease activity and risk of lymphoma in patients with rheumatoid arthritis nested case control study BMJ 317 1998 180 181
12. Y. Hoshida, Y. Tomita, D. Zhiming Lymphoproliferative disorders in autoimmune diseases in Japan analysis of clinicopathological features and Epstein Barr virus infection Int J Cancer 108 2004 443 449
13. X. Mariette, D. Cazals-Hatem, J. Warszawki Lymphomas in rheumatoid arthritis patients treated with methotrexate a 3 year prospective study in France Blood 99 2002 3909 3915
14. O. Kamel, M. van de Rijn, L. Weiss Reversible lymphomas associated with Epstein Barr virus occurring during methotrexate therapy for rheumatoid arthritis or dermatomyositis N Engl J Med 328 1993 1317 1321
15. American College of Rheumatology. http://www.rheumatology.org/ publications/hotline/0303TNFL.asp?aud=mem. Accessed February 10, 2005.
16. F. Wolfe, K. Michaud Lymphoma in rheumatoid arthritis. The effect of methotrexate and anti tumor necrosis factor therapy in 18572 patients Arthritis Rheum 50 6 2004 1740 1751