Cleavage of apolipoprotein E by membrane-type matrix metalloproteinase-1 abrogates suppression of cell proliferation

Journal of Biochemistry

Volumn 137, Issue 1, 2005, Pages 95-99

  Aoki, Takanori ^a,b   Sato, Daisuke ^a   Li, Yingyi ^a   Takino, Takahisa ^a   Miyamori, Hisashi ^a   Sato, Hiroshi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b Daiichi Fine Chemical Co Ltd   (Japan)

Author keywords

Apolipoprotein E; Cell proliferation; Cleavage; MMP; MT1 MMP

Indexed keywords

ALANINE; APOLIPOPROTEIN E; ARGININE; BATIMASTAT; COMPLEMENTARY DNA; GELATINASE A; GLUTAMIC ACID; GLUTATHIONE TRANSFERASE; GLYCINE; INTERSTITIAL COLLAGENASE; LEUCINE; LYSINE; MATRIX METALLOPROTEINASE INHIBITOR; METHIONINE; RECOMBINANT PROTEIN; SERINE; THREONINE;

ARTICLE; CELL PROLIFERATION; CELL STRAIN HEK293; CELL STRAIN HT29; DISSOCIATION; DNA LIBRARY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOSIS INHIBITION; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

APOLIPOPROTEINS E; CELL LINE; CELL PROLIFERATION; GENE EXPRESSION; HUMANS; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; PHENYLALANINE; PROTEASE INHIBITORS; THIOPHENES;

EID: 17044370897     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/jb/mvi009     Document Type: Article

References (27)

1. Mahley, R.W. (1988) Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 240, 622-630
2. Curtiss, L.K. and Boisvert, W.A. (2000) Apolipoprotein E and atherosclerosis. Curr. Opin. Lipidol. 11, 243-251
3. Mahley, R.W. and Ji, Z.S. (1999) Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E. J Lipid Res. 40, 1-16
4. Curtiss, L.K. (2000) ApoE in atherosclerosis: a protein with multiple hats. Arterioscler. Thromb. Vasc. Biol. 20, 1852-1853
5. Swertfeger, D.K. and Hui, D.Y. (2001) Apoprotein E: a cholesterol transport protein with lipid transport-independent cell signaling properties. Frontiers in Bioscience 6, d526-d535
6. Hui, D.Y., Harmony, J.A.K., Innerarity, T.L., and Mahley, R.W. (1980) Immunoregulatory plasma lipoproteins. Role of apoprotein E and apoprotein B. J Biol. Chem. 255, 11775-11781
7. Pepe, M.G. and Curtiss L.K. (1986) Apolipoprotein E is a biologically active constituent of the normal immunoregulatory lipoprotein, LDL-In. J. Immunol. 136, 3716-3723
8. Riddell, D.R. and Owen, J.S. (1996) Inhibition of ADP-induced platelet aggregation by apoE is not mediated by membrane cholesterol depletion. Thromb. Res. 81, 597-606
9. Riddell, D.R., Graham, A., and Owen, J.S. (1997) Apolipoprotein E inhibits platelet aggregation through the L-arginine: nitric oxide pathway. Implications for vascular disease. J. Biol. Chem. 272, 89-95
10. Ishigami, M., Swertfeger, D.K., Granholm, N., and Hui, D.Y. (1998) Apolipoprotein E inhibits platelet-derived growth factor-induced vascular smooth muscle cell migration and proliferation by suppressing signal transduction and preventing cell entry to G1 phase, J. Biol. Chem. 273, 20156-20161
11. Ishigami, M., Swertfeger, D.K., Hui, M.S., Granholm, N.A., and Hui, D.Y. (2000) Apolipoprotein E inhibition of vascular smooth muscle cell proliferation but not the inhibition of migration is mediated through activation, of inducible nitric oxide synthase. Arterioscler. Thromb. Vasc. Biol. 20, 1020-1026
12. Woessner, J.F. Jr. (1991) Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J. 5, 2145-2154
13. Birkedal, H.H., Moore, W.G., Bodden, M.K., Windsor, L.J., Birkedal, H.B., DeCarlo, A., and Engler, J.A. (1993) Matrix metalloproteinases: a review. Crit. Rev. Oral Biol. Med. 4, 197-250
14. Seiki, M. (1999) Membrane-type matrix metalloproteinases. APMIS 107, 137-143
15. Nagase, H. and Woessner, J.F. Jr. (1999) Matrix metalloproteinases. J. Biol. Chem. 274, 21491-21494
16. Galis, Z.S. and Khatri, J.J. (2002) Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly. Circ. Res. 90, 251-262
17. Rajavashisth, T.B., Xu, X.P., Jovinge, S., Meisel, S., Xu, X.O., Chai, N.N., Fishbein, M.C., Kaul, S., Cercek, B., Sharifi, B., and Shah, P.K. (1999) Membrane type 1 matrix metalloproteinase expression in human atherosclerotic plaques: evidence for activation by proinflammatory mediators. Circulation 99, 3103-3109
18. Kinoshita, T., Sato, H., Okada, A., Ohuchi, E., Imai, K., Okada, Y., and Seiki, M. (1998) TIMP-2 promotes activation of progelatinase A by membrane-type 1 matrix metalloproteinase immobilized on agarose beads. J. Biol. Chem. 273, 16098-16103
19. Shimada, T., Nakamura, H., Ohuchi, E., Fujii, Y., Murakami, Y., Sato, H., Seiki, M., and Okada, Y. (1999) Characterization of a truncated recombinant form of human membrane type 3 matrix metalloproteinase. Eur. J. Biochem. 262, 907-914
20. Miyamori, H., Takino, T., Kobayashi, Y., Tokai, H., Itoh, Y., Seiki, M., and Sato, H. (2001) Claudin promotes activation of pro-matrix metalloproteinase-2 mediated by membrane-type matrix metalloproteinases. J. Biol. Chem. 276, 28204-28211
21. Sato, H., Takino, T., Okada, Y., Cao, J., Shinagawa, A., Yamamoto, E., and Seiki, M. (1994) A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature 370, 61-65
22. Swertfeger, D.K. and Hui, D.Y. (2001) Apolipoprotein E receptor binding versus heparan sulfate proteoglycan binding in its regulation of smooth muscle cell migration and proliferation. J. Biol. Chem. 276, 25043-25048
23. Takino, T., Koshikawa, N., Miyamori, H., Tanaka, M., Sasaki, T., Okada, Y., Seiki, M., and Sato, H. (2003) Cleavage of metastasis suppressor gene product KiSS-1 protein/metastin by matrix metalloproteinases. Oncogene 22, 4617-4626
24. Ohuchi, E., Imai, K., Fujii, Y., Sato, H., Seiki, M., and Okada, Y. (1997) Membrane-type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules. J. Biol. Chem. 272, 2446-2451
25. Ratnikov, B.I., Rozanov, E.V., Postnova, T.I., Baciu, P.G., Zhang, H., DiScipio, R.G., Chestukhina, G.G., Smith, J.W., Deryugina, E.I., and Strongin, A.Y (2002) An alternative processing of integrin αv subunit in tumor cells by membrane type-1 matrix metalloproteinase. J. Biol. Chem. 277, 7377-7385
26. Endo, K., Takino, T., Miyamori, H., Kinsen, H., Yoshizaki, T., Furukawa, M., and Sato, H. (2003) Cleavage of syndecan-1 by membrane type matrix metalloproteinase-1 stimulates cell migration. J. Biol. Chem. 278, 40764-40770
27. Tam, E.M., Morrison, C.J., Wu, Y.I., Stack, M.S., and Overall, C.M. (2004) Membrane protease proteomics: Isotope-coded affinity tag MS identification of undescribed MT1-matrix metalloproteinase substrates. Proc. Natl Acad. Sci. USA 101, 6917-6922