In vivo treatment with the K+ channel blocker 4-aminopyridine protects against kainate-induced neuronal cell death through activation of NMDA receptors in murine hippocampus

Neuropharmacology

Volumn 48, Issue 6, 2005, Pages 810-821

  Ogita, Kiyokazu ^a   Okuda, Hiroaki ^a   Watanabe, Mami ^a   Nagashima, Reiko ^a   Sugiyama, Chie ^a   Yoneda, Yukio ^b  

^a SETSUNAN UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

4 Aminopyridine; Deoxyribonuclease II; Kainate; Neuroprotection; NMDA receptor

Indexed keywords

4 AMINOPYRIDINE; 8 CYCLOPENTYLTHEOPHYLLINE; ADENOSINE A1 RECEPTOR ANTAGONIST; DEOXYRIBONUCLEASE II; DIZOCILPINE; DNA FRAGMENT; KAINIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; POTASSIUM CHANNEL BLOCKING AGENT; PROTEIN C FOS; SINGLE STRANDED DNA;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL;

EID: 16844369151     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2004.12.018     Document Type: Article

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