Risk for K-ras gene mutations in smoking-induced lung cancer is associated with cytochrome P4501A1 and glutathione S-transferase μ1 polymorphisms

Oncology Reports

Volumn 12, Issue 4, 2004, Pages 773-779

  Noda, Naotaka ^a   Matsuzoe, Daisuke ^a   Konno, Toshikazu ^a   Kawahara, Katsunobu ^a   Yamashita, Yuichi ^a   Shirakusa, Takayuki ^a  

^a FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Benzo a pyrene; Cigarette smoking; CYP1A1; GSTM1; K ras; Lung cancer; Polymorphism

Indexed keywords

CYTOCHROME P450 1A1; DNA; GLUTATHIONE S-TRANSFERASE M1; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; ENZYMOLOGY; FEMALE; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HUMAN; LUNG NON SMALL CELL CANCER; LUNG TUMOR; MALE; MIDDLE AGED; MUTATION; ONCOGENE RAS; SMOKING; SQUAMOUS CELL CARCINOMA;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CYTOCHROME P-450 CYP1A1; DNA, NEOPLASM; FEMALE; GENES, RAS; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUTATION; POLYMORPHISM, GENETIC; SMOKING;

EID: 16644401351     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.12.4.773     Document Type: Article

References (37)

1. Hayashi S, Watanabe J, Nakachi K and Kawajiri K: Genetic linkage of lung cancer-associated Msp-1 polymorphisms with amino acid replacement in the heme binding region of the human cytochrome P450IA1 gene. J Biochem 110: 407-411, 1991.
2. Nakachi K, Imai K, Hayashi S, Watanabe J and Kawajiri K: Genetic susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose. Cancer Res 51: 5177-5180, 1991.
3. Nakachi K, Imai K, Hayashi S and Kawajiri K: Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population. Cancer Res 53: 2994-2999, 1993. (Pubitemid 23210302)
4. Nebert DW, McKinnon RA and Puga A: Human drug metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer. DNA Cell Biol 15: 273-280, 1996. (Pubitemid 26124084)
5. Gonzalez FJ: The role of carcinogen-metabolizing enzyme polymorphisms in cancer susceptibility. Reprod Toxicol 11: 397-412, 1997.
6. Hirvonen A, Pursianen KH, Karjalainen A, Anttila S and Vainio H: Point-mutational Mspl and Ile/Val polymorphisms closely linked in the CYP1A1 gene: lack of association with susceptibility to lung cancer in a Finnish study population. Cancer Epidemiol Biomarkers Prev 1: 485-489, 1992.
7. Alexandrie AK, Sundberg MI, Seidegard J, Tornling G and Rannug A: Genetic susceptibility to lung cancer with special emphasis to CYP1A1 and GSTM1: a study on host factors in relation to age at onset, gender and histological cancer types. Carcinogenesis 15: 1785-1790, 1994.
8. Pearson WR, Vorachek WR, Xu S, et al: Identification of classmu glutathione transferase genes GSTM1-GSTM5 on human chromosome lpl3. Am J Hum Genet 53: 220-233, 1993. (Pubitemid 23313753)
9. Lin HJ, Han CY, Bernstein DA, Hsiao W, Lin BK and Hardy S: Ethnic distribution of the glutathione transferase Mu 1-1 (GSTM1) null genotype in 1473 individuals and application to bladder cancer susceptibility. Carcinogenesis 15: 1077-1081, 1994. (Pubitemid 24156914)
10. Dialyna IA, Miyakis S, Georgatou N and Spandidos DA: Genetic polymorphisms of CYP1A1, GSTM1, and GSTT1 genes and lung cancer risk. Oncol Rep 10: 1829-1835, 2003.
11. Seidegard J, Pero RW, Markowitz MM, Roush G, Miller DG and Beattie EJ: Isoenzyme(s) of glutathione transferase (class Mu) as a marker for the susceptibility to lung cancer: a follow-up study. Carcinogenesis 11: 33-36, 1990. (Pubitemid 20050732)
12. Nazar-Stewart V, Motulsky AG, Eaton DL, et al: The glutathione S-transferase p polymorphism as a marker for susceptibility to lung carcinoma. Cancer Res 53: 2313-2318, 1993. (Pubitemid 23156818)
13. Hirvonen A, Husgafvel-Pursiainen K, Anttila S and Vainio H: The GSTM1 null genotype as a potential risk modifier for squamous cell carcinoma of the lung. Carcinogenesis 14: 1479-1481, 1993. (Pubitemid 23229700)
14. Matsuzoe D, Hideshima T, Iwasaki A, et al: Glutathione S-transferase μ1 null genotype is associated with K-ras gene mutation in lung adenocarcinoma among smokers. Carcinogenesis 22:1327-1330, 2001. (Pubitemid 32737352)
15. Heckbert SR, Weiss NS, Hornung SK, Eaton DL and Motulsky AG: Glutathione S-transferase and epoxide hydrolase activity in human leukocytesin relation to risk of lung cancer and other smoking-related cancers. J Natl Cancer Inst 84: 414-422, 1992.
16. Brockmoller J, Kerb R, Drakoulis N, Nitz M and Roots I: Genotype and phenotype of glutathione S-transferase class μ isoenzymes μ and ψ in lung cancer patients and controls. Cancer Res 53: 1004-1011, 1993. (Pubitemid 23087898)
17. Kiaris H and Spandidos DA: Mutations of ras genes in human tumours. Int J Oncol 7: 413-429, 1995.
18. Gao HG, Chen JK, Stewart J, et al: Distribution of p53 and K-ras mutations in human lung cancer tissues. Carcinogenesis 18: 473-478, 1997. (Pubitemid 28132482)
19. Rodenhuis S, Slebos RJ, Boot AJ, et al: Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung. Cancer Res 48: 5738-5741, 1988.
20. Hayashi SI, Watanabe J and Kawajiri K: High susceptibility to lung cancer analyzed in terms of combined genotypes of P4501A1 and Mu-class glutathione S-transferase genes. Jpn J Cancer Res 83: 866-870, 1992.
21. Comstock KE, Sanderson JS, Claflin G and Henner WD: GST1 gene deletion determined by polymerase chain reaction. Nucleic Acids Res 18:3670, 1990. (Pubitemid 20191848)
22. Weber JL, Kwitec AE and May PE: Dinucleotide repeat polymorphisms at the D16S260, D26S261, D16S265, D16S266, and D16S267 loci. Nucleic Acids Res 18: 4034, 1990. (Pubitemid 20222982)
23. Sato S, Nakamura Y and Tsuchiya E: Difference of allotype between squamous cell carcinoma and adenocarcinoma of the lung. Cancer Res 54: 5652-5655, 1994. (Pubitemid 24346262)
24. Kawajiri K, Nakachi K, Imai K, Yoshii A, Shinoda N and Watanabe J: Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P450IA1 gene. FEBS Lett 263: 131-133, 1990. (Pubitemid 20107795)
25. Song N, Tan W, Xing D and Lin D: CYP1A1 polymorphism and risk of lung cancer in relation to tobacco smoking: a casecontrol study in China. Carcinogenesis 22: 11-16, 2001. (Pubitemid 32098138)
26. Bouchardy C, Wikman H, Benhamous S, Hirvonen A, Dayer P and Husgafvel-Pursianinen K: CYP1A1 genetic polymorphisms, tobacco smoking and lung cancer risk in French Caucasian population. Biomarkers 2: 131-134, 1997. (Pubitemid 127699894)
27. Wu X, Shi H, Jiang H, et al: Association between cytochrome P4502E1 genotype, mutagen sensitivity, cigarette smoking and susceptibility to lung cancer. Carcinogenesis 18: 967-973, 1997. (Pubitemid 28132341)
28. Mihi Y. Brian FC, Robert D, Nicholas PL and Fred FK: Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue. Lung Cancer 38: 15-21, 2002.
29. Weinberg RA: Oncogenes, tumor suppressor genes, and cell transformation: trying to put it all together. In: Origins of Human Cancer: A Comprehensive Review. Brugge J, Curran T, Harlow ED and McCormick F (eds). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp1-16, 1991.
30. Rodenhuis S and Slebos RJ: Clinical significance of ras oncogene activation in human lung cancer. Cancer Res 52: 2665s-2669s, 1992.
31. Suzuki Y, Orita M, Shiraishi M, Hayashi K and Sekiya T: Detection of ras gene mutations in human lung cancers by single strand conformational polymorphism analysis of polymerase chain reaction products. Oncogene 5: 1037-1043, 1990.
32. Huang CL, Taki T, Adachi M, et al: Mutation of p53 and K-ras genes as prognostic factors for non-small cell lung cancer. Int J Oncol 12: 553-563, 1998. (Pubitemid 28097282)
33. Fukuyama Y, Mitsudomi T, Sugio K, Ishida T, Akazawa K, Sugimachi K: K-ras and p53 mutations are an independent unfavourable prognostic indicators in patients with non-small cell lung cancer. Br J Cancer 75: 1125-1130, 1997. (Pubitemid 27140022)
34. Mazur M and Glickma BW: Sequence specificity of mutations induced by benzo[a]pyrene-7,8-diol-9,10-epoxide at endogenous aprt gene in CHO cells. Somat Cell Mol Genet 14: 393-400, 1988.
35. Ryberg D, Skaug V, Hewer A, et al: Genotypes of glutathione transferase M1 and P1 and their significance for lung DNA adduct levels and cancer risk. Carcinogenesis 18: 1285-1289, 1997. (Pubitemid 28134699)
36. Kawajiri K, Eguchi H, Nakachi K, Sekiya T and Yamamoto M: Association of CYP1A1 germ line polymorphisms with mutations of the p53 gene in lung cancer. Cancer Res 56: 72-76, 1996. (Pubitemid 26010386)
37. Bartsch H, Nair U, Risch A, Rojas M, Wikman H and Alexandrov K: Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers (review). Cancer Epidemiol Biomarkers Prev 9: 3-28, 2000. (Pubitemid 30062906)