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Volumn 15, Issue 6, 2004, Pages 65-71

Enfuvirtide (T-20): Potentials and Challenges

Author keywords

adverse event; enfuvirtide; HAART; injection site reactions; optimized background (OB) regimen

Indexed keywords

ENFUVIRTIDE; GLYCOPROTEIN GP 41; HUMAN IMMUNODEFICIENCY VIRUS FUSION INHIBITOR; PEPTIDE FRAGMENT;

EID: 16644395197     PISSN: 10553290     EISSN: None     Source Type: Journal    
DOI: 10.1177/1055329003256414     Document Type: Article
Times cited : (9)

References (20)
  • 1
    • 33745943684 scopus 로고    scopus 로고
    • Ball, R. & Kinchelow, T. (2003) Pathology of injection site reactions with enfuvirtide (T-20). Abstract 714. Tenth Conference on Retroviruses and Opportunistic Infections, Boston.
  • 2
    • 0036776977 scopus 로고    scopus 로고
    • HIV genetic mutations causing resistance to the new drug T-20: Recent findings
    • Bean P. HIV genetic mutations causing resistance to the new drug T-20: Recent findings. American Clinical Laboratory 21 8 (2002) 15-16
    • (2002) American Clinical Laboratory , vol.21 , Issue.8 , pp. 15-16
    • Bean, P.1
  • 3
    • 33745964258 scopus 로고    scopus 로고
    • Boyd, M., Ruxrungtham K., Zhang X., Bellibas S. E., Buss N. E. & Patel, I. H. (2003) Enfuvirtide-investigations on the drug interaction potential in HIV-infected patients. Abstract 541. Tenth Conference on Retroviruses and Opportunistic Infections, Boston.
  • 4
    • 0030970693 scopus 로고    scopus 로고
    • Core structure of gp41 from the HIVenvelope glycoprotein
    • Chan D.C., Fass D., Berger J.M., and Kim P.S. Core structure of gp41 from the HIVenvelope glycoprotein. Cell 89 (1997) 263-273
    • (1997) Cell , vol.89 , pp. 263-273
    • Chan, D.C.1    Fass, D.2    Berger, J.M.3    Kim, P.S.4
  • 5
    • 33745968492 scopus 로고    scopus 로고
    • Clotet, B., Lazzarin A., Cooper D., Reynes J., Arasteh K., Nelson M., et al (2002) Enfuvirtide (T-20) in combination with an optimized background (OB) regimen vs. OB alone in patients with prior experience or resistance to each of the three classes of approved antiretrovirals (ARVs) in Europe and Australia. Abstract LbOr19A. Fourteenth International Aids Conference, Barcelona, Spain.
  • 6
    • 0036315615 scopus 로고    scopus 로고
    • Long-term treatment with subcutaneous T-20, a fusion inhibitor, in HIV-infected patients: Patient satisfaction and impact on activities of daily living
    • Cohen C.J., Dusek A., Green J., Johns E.L., Nelson E., and Recny M.A. Long-term treatment with subcutaneous T-20, a fusion inhibitor, in HIV-infected patients: Patient satisfaction and impact on activities of daily living. AIDS Patient Care STDS 16 7 (2002) 327-335
    • (2002) AIDS Patient Care STDS , vol.16 , Issue.7 , pp. 327-335
    • Cohen, C.J.1    Dusek, A.2    Green, J.3    Johns, E.L.4    Nelson, E.5    Recny, M.A.6
  • 7
    • 33745935070 scopus 로고    scopus 로고
    • Delfraissy, J-F., Montaner J., Eron J., DeMasi R., Chung J, Drobnes C., et al: (2003) Summary of pooled efficacy and safety analyses of enfuvirtide (ENF) treatment for 24 weeks in TORO 1 and TORO 2 Phase III trials in highly antiretroviral (ARV) treatment experienced patients. Abstract 568. Tenth Conference on Retroviruses and Opportunistic Infections, Boston.
  • 8
    • 33745966348 scopus 로고    scopus 로고
    • Drobnes, C., Fang L., Nelson E., True A., Salgo M. & Delehanty, J. (2002) Tolerability of enfuvirtide (T-20) during chronic therapy in Phase II trials. Abstract 171. Forty-second Interscience Conference on Anti-microbial Agents and Chemotherapy, San Diego, CA.
  • 9
    • 33745963273 scopus 로고    scopus 로고
    • Green, J., Wintfeld, N. (2002) Patients acceptance with selfinjection of enfuvirtide (T-20) for HIV over 24 weeks of treatment. Abstract P48. Sixth International Congress on Drug Therapy in HIV Infection, Glasgow, Scotland.
  • 10
    • 33745942929 scopus 로고    scopus 로고
    • Greenberg, M. L., Melby T., Sista P., DeMasi R., Cammack N., Salgo M., et al: (2003), Baseline and on-treatment susceptibility to enfuvirtide seen in TORO 1 and TORO 2 to 24 weeks. Abstract 141. Tenth Conference on Retroviruses and Opportunistic Infections, Boston.
  • 11
    • 33745943883 scopus 로고    scopus 로고
    • Henry, K., Lalezari J., OHearn M., Trottier B., Montaner J., Piliero P., et al: (2002) Enfuvirtide (T-20) in combination with an optimized background (OB) regimen vs. OB alone in patients with prior experience or resistance to each of the three classes of approved antiretrovirals (ARVs) in North America and Brazil. Abstract LbOr19B. Fourteenth International Aids Conference, Barcelona, Spain.
  • 12
    • 33745941438 scopus 로고    scopus 로고
    • Hirschler B. (2003) Record high price set for new Roche AIDS drug. Retrieved from http://www.aidsmeds.com/news/20030224inds001.html
  • 13
    • 33745946734 scopus 로고    scopus 로고
    • Hornberger, J. & Green, J. (2002) Modeling the clinical prognosis of patients receiving enfuvirtide (T-20) in combination with an optimized background regimen according to virological and immunological response after 24 weeks. Abstract P40. Sixth International Congress on Drug Therapy in HIV infection, Glasgow, Scotland.
  • 14
    • 0032543307 scopus 로고    scopus 로고
    • Structure of an HIV gp120 envelope glycoprotein in complex with the CD4+ receptor and a neutralizing antibody
    • Kwong P.D., Wyatt R., Robinson J., Sweet R.W., Sodroski J., and Hendrickson W.A. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4+ receptor and a neutralizing antibody. Nature 393 (1998) 648-659
    • (1998) Nature , vol.393 , pp. 648-659
    • Kwong, P.D.1    Wyatt, R.2    Robinson, J.3    Sweet, R.W.4    Sodroski, J.5    Hendrickson, W.A.6
  • 15
    • 0037539498 scopus 로고    scopus 로고
    • Fitness of HIV-1 clinical isolates resistant to T-20 (enfuvirtide)
    • Abstract 67
    • Lu J., Sista P., Cammack N., and Kuritzkes D. Fitness of HIV-1 clinical isolates resistant to T-20 (enfuvirtide). Antiviral Therapy 7 S56 (2002) Abstract 67
    • (2002) Antiviral Therapy , vol.7 , Issue.SUPPL.56
    • Lu, J.1    Sista, P.2    Cammack, N.3    Kuritzkes, D.4
  • 17
    • 33745933361 scopus 로고    scopus 로고
    • Roche Pharmaceutical. (2002, December 18). Update on the manufacture of new HIV drug, Fuzeon. Media release.
  • 20
    • 0027692502 scopus 로고
    • A synthetic peptide from HIV-1 gp41 is a potent inhibitor of virus-mediated cell-cell fusion
    • Wild C., Greenwell T., and Matthews T. A synthetic peptide from HIV-1 gp41 is a potent inhibitor of virus-mediated cell-cell fusion. AIDS Research and Human Retroviruses 9 (1993) 1051-1053
    • (1993) AIDS Research and Human Retroviruses , vol.9 , pp. 1051-1053
    • Wild, C.1    Greenwell, T.2    Matthews, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.