Closed loop stimulation in prevention of vasovagal syncope. Inotropy controlled pacing in vasovagal syncope (INVASY): A multicentre randomized, single blind, controlled study

Europace

Volumn 6, Issue 6, 2004, Pages 538-547

  Occhetta, Eraldo ^a,ad   Bortnik, Miriam ^a   Audoglio, Roberto ^b   Vassanelli, Corrado ^a   Roncarolo, Pierluigi ^c   Chiodi, Leandro ^d   Marcolongo, Marco ^e   Torta, Davide ^e   Zanetta, Marco ^f   Boriani, Guiseppe ^g   Pirisi, Raimondo ^h   Mazza, Antonio ⁱ   Marconi, Paolo ^j   Igidbashian, Diran ^k   Romano, Salvatore ^l   Manfredini, Ruggero ^l   Tondo, Claudio ^m   Arlotti, Massimo ⁿ   Chimienti, Marcello ⁿ   Zamparelli, Luigi ^o   Cioffi, Luciano ^o   Carboni, Angelo ^p   Bongiorni, Maria Grazia ^q   Polimeni, Rocco ^r   Sermasi, Sergio ^e   Del Giudice, Giovanni ^s   Croce, Adriano ^t   Batista Tola, Giovanni ^d   Terrosu, Pierfranco ^d   Bellotti, Paolo ^u   Gazzarata, Massimo ^u   Libero, Luigi ^v   Jorfida, Marcella ^v   Bensoni, Mauro ^w   Barbieri, Daniela ^x   Lombroso, Sergio ^x   Galati, Antonio ^y   Salerno, Jorge ^z   Caico, Salvatore ^z   Bianchi, Enzo Maria ^aa   Glenzer, Renato ^aa   Zolezzi, Francesco ^ab   Negro, Roberto ^ab   Sassara, Massimo ^ac   De Luca, Fernando ^ac   more..

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^b SRA Linarolo   (Italy)

^c Ospedale Civile   (Italy)

^d SS Annunziata Hospital   (Italy)

^e OSPEDALE DEGLI INFERMI   (Italy)

^f Ospedale SS Trinita   (Italy)

^g UNIVERSITY OF BOLOGNA   (Italy)

^h Ospedale S Giovani   (Italy)

ⁱ Ospedale Civile Di Vicenza   (Italy)

^j CAREGGI UNIVERSITY HOSPITAL   (Italy)

^k Ospedale Civile   (Italy)

^l FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^m CENTRO CARDIOLOGICO MONZINO   (Italy)

ⁿ Policlinico   (Italy)

^o MONALDI HOSPITAL   (Italy)

^p Azienda Ospedaliera   (Italy)

^q CISANELLO HOSPITAL   (Italy)

^r Ospedale S Maria degli Ungeresi   (Italy)

^s SAN GIOVANNI ADDOLORATA HOSPITAL   (Italy)

^t Azienda USSL 4 Saronno (Varese)   (Italy)

^u Dipartimento Interaziendale di Neuroscienze del Ponente Ligure   (Italy)

^v MAGGIORE HOSPITAL   (Italy)

^w S GIOVANNI BOSCO HOSPITAL   (Italy)

^x Opedale Galmarini   (Italy)

^y UO Ostetricia Ginecologia   (Italy)

^z OSPEDALE DI CIRCOLO   (Italy)

^aa Stabilimento Ospedaliero Castelli   (Italy)

^ab Ospedale Civile   (Italy)

^ac BELCOLLE HOSPITAL   (Italy)

^ad Azienda Ospedaliera Universitaria Maggiore Della Carita   (Italy)

more..

Author keywords

Closed loop stimulation; DDD pacing; Vasovagal syncope

Indexed keywords

INOTROPIC AGENT;

ADULT; AGED; ARTICLE; ARTIFICIAL HEART PACEMAKER; BRADYCARDIA; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIAGNOSTIC PROCEDURE; DISEASE SEVERITY; FEMALE; FOLLOW UP; HEART MUSCLE CONTRACTILITY; HEART PACING; HEART RATE; HEART VENTRICLE FILLING; HUMAN; HYPOTENSION; INTERMETHOD COMPARISON; MALE; MULTICENTER STUDY; PRESSORECEPTOR; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; RECURRENT DISEASE; SINGLE BLIND PROCEDURE; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; SYNCOPE; TILT TABLE TEST; ELECTROSTIMULATION THERAPY; HEART ARRHYTHMIA; METHODOLOGY; MIDDLE AGED; PATHOPHYSIOLOGY;

ADULT; AGED; ARRHYTHMIA; ELECTRIC STIMULATION THERAPY; FEMALE; HUMANS; MALE; MIDDLE AGED; PACEMAKER, ARTIFICIAL; RECURRENCE; SINGLE-BLIND METHOD; SYNCOPE, VASOVAGAL; TILT-TABLE TEST;

EID: 16644394121     PISSN: 10995129     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eupc.2004.08.009     Document Type: Article

References (34)

1. J.D. Maloney F.J. Jaeger F.M. Fouad-Tarazi H.H. Morris Malignant vasovagal syncope prolonged asystolie provoked by head-up tilt Cleveland Clin Med J 55 1988 542-8
2. R. Sutton Vasovagal syndrome. Could it be malignant? Eur J Cardiac Pacing Electrophysiol 2 1992 89
3. K.A. Ellenbogen C.A. Morillo M.A. Wood et al. Neural monitoring of vasovagal syncope Pacing Clin Electrophysiol 20 1997 788-94
4. J.S. Sra M.R. Jazayeri B. Avitall et al. Comparison of cardiac pacing with drug therapy in the treatment of neurocardiogenic (vasovagal) syncope with bradycardia or asystole N Engl J Med 328 1993 1085-90
5. M.E. Petersen R. Chamberlain-Webber A.P. Fitzpatrick et al. Permanent pacing for cardioinhibitory malignant vasovagal syncope Br Heart J 71 1994 274-81
6. H.L. Thomson J.J. Atherton F.A. Khafagi M.P. Frenneaux Failure of reflex venoconstriction during exercise in patients with vasovagal syncope Circulation 93 1996 953-9
7. T.M. Lee M.F. Chen S.F. Su et al. Excessive myocardial contraction in vasovagal syncope demonstrated by echocardiography during head-up tilt Clin Cardiol 19 1996 137-40
8. K.J. Quan M.D. Carlson M.D. Thames Mechanisms of heart rate and arterial blood pressure control: Implications for the pathophysiology of neurocardiogenic syncope Pacing Clin Electrophysiol 20 1997 764-74
9. J.S. Sra V. Murthy A. Natale et al. Circulatory and catecholamines changes during head up tilt testing in neurocardiogenic (vasovagal) syncope Am J Cardiol 73 1994 33-7
10. M.E.V. Petersen T.R. Williams M. Erickson R. Sutton Right ventricular pressure, dP/dt, and preejection interval during tilt induced vasovagal syncope Pacing Clin Electrophysiol 20 1997 806-9
11. R. Mosqueda-Garcia R. Furlan R.F. Violante et al. Sympathetic and baroreceptor reflex function in neurally mediated syncope evoked by tilt J Clin Invest 99 1997 2736-44
12. M. Schaldach H. Hutten Intracardiac impedance to determine sympathetic activity in rate responsive pacing Pacing Clin Electrophysiol 15 1992 1778-86
13. max and intracardiac impedance during dobutamine stress test Pacing Clin Electrophysiol 23 2000 1502-8
14. A.P. Ravazzi G. Carosio P. Diotallevi et al. Clinical assessment of the correlation between right ventricular impedance and left ventricular contractility Prog Biomed Res 5 2000 478-81
15. A. Da Costa M. Ostermeier M. Schaldach K. Isaaz Closed loop pacing in a young patient with vasovagal syncope during tilt test Arch Mal Coeur Vaiss 91 Suppl III 1998 48 [abstract]
16. E. Occhetta M. Bortnik P. Paffoni et al. Closed loop stimulation in neuromediated syncope Meditteranean Soc Pacing Electrophysiol J 1 1999 143-8
17. Occhetta E, Bortnik M, Paffoni P, et al. Neurohumoral effects on closed loop stimulation. In: Santini M, editor. Seventh International Symposium on Progress in Clinical Pacing. CEPI ed. Rome; 1998. p. 39-43.
18. E. Occhetta M. Bortnik C. Vassanelli et al. The DDDR closed loop stimulation for the prevention of vasovagal syncope: Results from the INVASY prospective feasibility registry Europace 5 2003 153-62
19. R. Sutton M. Brignole C. Menozzi et al. Dual-chamber pacing in the treatment of neurally mediated tilt-positive cardioinhibitory syncope Circulation 102 2000 294-303
20. E. Occhetta M.G. Bongiorni L. Chiodi et al. Studio INVASY Protocollo di studio clinico per la valutazione della stimolazione CLS nella prevenzione delle sincopi neuromediate di tipo cardioinibitorio e misto (sincope vasovagale) G Ital Aritmol Cardiostim 1 2001 28-36
21. A. Fitzpatrick R. Sutton Tilting towards a diagnosis in recurrent unexplained syncope Lancet 1 1989 658-60
22. A. Fitzpatrick G. Theodorakis P. Vardas et al. Methodology of head-up tilt testing in unexplained syncope J Am Coll Cardiol 17 1991 125-30
23. A. Raviele C. Menozzi M. Brignole et al. Value of head-up tilt testing potentiated with sublingual nitroglycerin to assess the origin of unexplained syncope Am J Cardiol 76 1995 267-72
24. M. Shumacher M. Olschewski G. Schulgen Assessment of quality of life in clinical trials Stat Med 10 1991 1915-30
25. M.A. Testa D.C. Simonson Assessment of quality of life outcomes N Engl J Med 334 1996 835-40
26. S.J. Connolly R. Sheldon R.S. Roberts et al. The North American vasovagal pacemaker study (VPS). A randomized trial of permanent cardiac pacing for the prevention of vasovagal syncope J Am Coll Cardiol 33 1 1999 16-20
27. S.J. Connolly R. Sheldon K.E. Thorpe et al. Pacemaker therapy for prevention of syncope in patients with recurrent severe vasovagal syncope. Second vasovagal pacemaker study (VPS II): A randomized trial JAMA 289 17 2003 2224-9
28. F. Ammirati F. Colivicchi M. Santini Permanent cardiac pacing versus medical treatment for the prevention of recurrent vasovagal syncope Circulation 104 2001 52-63
29. R. Sheldon M.L. Koshman W. Wilson et al. Effect of dual-chamber pacing with automatic rate-drop sensing on recurrent neurally mediated syncope Am J Cardiol 81 1998 158-62
30. D. Benditt R. Sutton M. Gammage et al. Clinical experience with Thera DR rate-drop response pacing algorithm in carotid sinus syndrome and vasovagal syncope Pacing Clin Electrophysiol 20 1997 832-9
31. E. Occhetta M. Bortnik P. Paffoni et al. Closed loop stimulation in vasovagal syncope - one year follow-up in selected patients Prog Biomed Res 4 1999 176-80
32. L. Griesbach T. Huber B. Knote et al. Closed loop stimulation: Therapy for malignant neurocardiogenic syncope Prog Biomed Res 7 2002 242-7
33. Guyomar Y, Graux P, Nicolas E, et al. INOS2 DR and neurocardiogenic syncope: A first experience about four patients. In: Adornato E, editor. Rhythm control from cardiac evaluation to treatment. Proceedings Of the Sixth Southern Symposium on Cardiac Pacing (Taormina 1998). L. Pozzi ed., vol. 2. Roma; 1998. p. 170-5.
34. A.S. Kurbaan A.C. Franzén T.J. Bowker et al. Usefulness of tilt test-induced patterns of heart rate and blood pressure using a two-stage protocol with glyceryl trinitrate provocation in patients with syncope of unknown origin Am J Cardiol 84 1999 665-70