Effect of variations in the structure of a polyleucine-based α-Helical transmembrane peptide on its interaction with phosphatidylethanolamine bilayers

Biophysical Journal

Volumn 87, Issue 4, 2004, Pages 2470-2482

  Liu, Feng ^a   Lewis, Ruthven N A H ^a   Hodges, Robert S ^a,b   McElhaney, Ronald N ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(LA)12 PEPTIDE; MEMBRANE PROTEIN; PEPTIDE; PHOSPHATIDYLETHANOLAMINE; POLYLEUCINE;

ARTICLE; ARTIFICIAL MEMBRANE; BINDING SITE; CHEMISTRY; LIPID BILAYER; MACROMOLECULE; MEMBRANE FLUIDITY; PHASE TRANSITION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; TEMPERATURE;

BINDING SITES; LIPID BILAYERS; MACROMOLECULAR SUBSTANCES; MEMBRANE FLUIDITY; MEMBRANE PROTEINS; MEMBRANES, ARTIFICIAL; PEPTIDES; PHASE TRANSITION; PHOSPHATIDYLETHANOLAMINES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; TEMPERATURE;

EID: 16644377766     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1529/biophysj.104.046342     Document Type: Article

References (49)

1. Axelsen, P. H., B. K. Kaufman, R. N. McElhaney, and R. N. A. H. Lewis. 1995. The infrared dichroism of transmembrane helical polypeptides. Biophys. J. 69: 2770-2781.
2. Bogdanov, M., and W. Dowhan. 1998. Phospholipid-assisted protein folding: phosphatidyl-ethanolamine is required at a late step of the conformational maturation of the polytopic membrane protein lactose permease. EMBO J. 17: 5255-5264. (Pubitemid 28427041)
3. Boggs, J. M. 1980. Intermolecular hydrogen bonding between lipids: influence on organization and function of lipids in membranes. Can. J. Biochem. 58: 755-770.
4. Boggs, J. M. 1986. Effect of lipid structural modifications on their intermolecular hydrogen bonding interactions and membrane function. Biochem. Cell Biol. 64: 50-67.
5. Boggs, J. M. 1987. Lipid intermolecular hydrogen bonding: influence on structural organization and membrane function. Biochim. Biophys. Acta. 906: 353-404. (Pubitemid 17140656)
6. Bolen, E. J., and P. W. Holloway. 1990. Quenching of tryptophan fluorescence by brominated phospholipid. Biochemistry. 29: 9638-9643. (Pubitemid 20355212)
7. Chirgadze, Y. N., and E. V. Brazhnikov. 1974. Intensities and other spectral parameters of infrared amide bands of polypeptides in alpha helical form. Biopolymers. 13: 1701-1712.
8. Daum, G. 1985. Lipids of mitochondria. Biochim. Biophys. Acta. 822: 1-42. (Pubitemid 15042024)
9. Davis, J. H., D. M. Clare, R. S. Hodges, and M. Bloom. 1983. Interaction of a synthetic amphiphilic polypeptide and lipids in a bilayer structure. Biochemistry. 22: 5298-5305.
10. de Planque, M. R. R., and J. A. Killian. 2003. Protein-lipid interactions studied with designed transmembrane peptides: role of hydrophobic matching and interfacial anchoring. Mol. Membr. Biol. 20: 271-284.
11. Devaux, P. F., and M. Seigneuret. 1985. Specificity of lipid-protein interaction as determined by spectroscopic techniques. Biochim. Biophys. Acta. 822: 63-125.
12. Gennis, R. B. 1989. Membrane dynamics and protein-lipid interactions. In Biomembranes: Molecular Structure and Function. Springer-Verlag, New York. 166-198.
13. Huschilt, J. C., R. S. Hodges, and J. H. Davis. 1985. Phase equilibria in an amphiphilic peptide-phospholipid model membrane by deuterium nuclear magnetic resonance difference spectroscopy. Biochemistry. 24: 1377-1386.
14. Huschilt, J. C., B. M. Millman, and J. H. Davis. 1989. Orientation of alphahelical peptides in a lipid bilayer. Biochim. Biophys. Acta. 979: 139-141.
15. Jones, M. R., P. K. Fyfe, A. W. Roszak, N. W. Isaacs, and R. J. Cogdell. 2002. Protein-lipid interactions in the purple bacterial reaction center. Biochim. Biophys. Acta. 1565: 206-214. (Pubitemid 35284476)
16. Killian, J. A., and G. von Heijne. 2000. How proteins adapt to a membranewater interface. Trends Biochem. Sci. 25: 429-434. (Pubitemid 30662410)
17. Kleinschmidt, J. H. 2003. Membrane proteins-introduction. Cell. Mol. Life Sci. 60: 1527-1528.
18. Lewis, R. N. A. H., N. Mak, and R. N. McElhaney. 1987. A differential scanning calorimetric study of the thermotropic phase behavior of model membranes composed of phosphatidylcholines containing linear saturated acyl chains. Biochemistry. 26: 6118-6126.
19. Lewis, R. N. A. H., and R. N. McElhaney. 1993. Calorimetric and spectroscopic studies of the polymorphic phase behavior of a homologous series of n-saturated, 1,2-diacyl phosphatidyl-ethanolamines. Biophys. J. 64: 1081-1096. (Pubitemid 23143273)
20. Lewis, R. N. A. H., and R. N. McElhaney. 1996. FTIR spectroscopy in the study of hydrated lipids and lipid bilayer membranes. In Infrared Spectroscopy of Biomolecules. H. H. Mantsch and D. Chapman, editors. John Wiley & Sons, New York. 159-202.
21. Lewis, R. N. A. H., and R. N. McElhaney. 2002. Vibrational spectroscopy of lipids. In The Handbook of Vibrational Spectroscopy, Vol. 5. J. M. Chalmers and P. R. Griffiths, editors. John Wiley & Sons, New York. 3447-3464.
22. Liu, F., R. N. A. H. Lewis, R. S. Hodges, and R. N. McElhaney. 2002. Effect of variations in the structure of a polyleucine-based α-helical transmembrane peptide on its interaction with phosphatidylcholine bilayers. Biochemistry. 41: 9197-9207. (Pubitemid 34787277)
23. Liu, F., R. N. A. H. Lewis, R. S. Hodges, and R. N. McElhaney. 2004. Effect of variations in the structure of a polyleucine-based α-helical transmembrane peptide on its interaction with phosphatidylglycerol bilayers. Biochemistry. 43: 3679-3687. (Pubitemid 38391722)
24. Mantsch, H. H., C. Madec, R. N. A. H. Lewis, and R. N. McElhaney. 1985. The thermotropic phase behavior of model membranes composed of phosphatidylcholines containing isobranched fatty acids. II. Infrared and 31P-NMR spectroscopic studies. Biochemistry. 24: 2440-2446. (Pubitemid 15015748)
25. Marsh, D., and L. I. Horváth. 1998. Structure, dynamics and composition of the lipid-protein interface. Perspectives from spin-labelling. Biochim. Biophys. Acta. 1376: 267-296. (Pubitemid 28517881)
26. Monne, M., I. Nilsson, M. Johansson, N. Elmhed, and G. von Heijne. 1998. Positively and negatively charged residues have different effects on the position in the membrane of a model transmembrane helix. J. Mol. Biol. 284: 1177-1183. (Pubitemid 28558565)
27. Morrow, M. R., J. C. Huschilt, and J. H. Davis. 1985. Simultaneous modeling of phase and calorimetric behavior in an amphiphilic peptide/ phospholipid model membrane. Biochemistry. 24: 5396-5406. (Pubitemid 16228816)
28. 2H-nuclear magnetic resonance and Fourier transform infrared spectroscopy studies of the effects of transmembrane α-helical peptides on the organization of phosphatidylcholine bilayers. Biochim. Biophys. Acta. 1511: 60-73.
29. 2H-NMR. Eur. Biophys. J. 12: 1-11.
30. Pomorski, T., R. Lombardi, H. Riezman, P. F. Devaux, G. van Meer, and J. C. M. Holthuis. 2003. Drs2p-related P-type ATPases Dnf1p and Dnf2p are required for phospholipid translocation across the yeast plasma membrane and serve a role in endocytosis. Mol. Biol. Cell. 14: 1240-1254. (Pubitemid 36337466)
31. Rabolt, J. F., W. H. Moore, and S. Krimm. 1977. Vibrational analysis of peptides, polypeptides and proteins. 3. alpha-Poly(L-alaninr). Macromolecules. 10: 1065-1074.
32. Ren, J., S. Lew, Z. Wang, and E. London. 1997. Transmembrane orientation of hydrophobic α-helices is regulated both by the relationship of helix length to bilayer thickness and by the cholesterol concentration. Biochemistry. 36: 10213-10220. (Pubitemid 27357732)
33. Segrest, J. P., H. de Loof, J. G. Dohlman, C. G. Brouillette, and G. M. Anantharamaiah. 1990. Amphipathic helix motif: classes and properties. Proteins. 8: 103-117. (Pubitemid 20262536)
34. Selinsky, B. S. 1992. Protein-lipid interactions and membrane function. In The Structure of Biological Membranes. P. Yeagle, editor. CRC Press, Boca Raton, FL. 603-651.
35. Sperotto, M. M., and O. G. Mouritsen. 1988. Dependence of lipid-membrane phase-transition temperature on the mismatch of protein and lipid hydrophobic thickness. Eur. Biophys. J. 16: 1-10.
36. Subczynski, W. K., R. N. A. H. Lewis, R. N. McElhaney, R. S. Hodges, J. S. Hyde, and A. Kusumi. 1998. Molecular organization and dynamics of 1-palmitoyl-2-oleoyl-phosphatidylcholine bilayers containing a transmembrane α-helical peptide. Biochemistry. 37: 3156-3164. (Pubitemid 28145770)
37. Subczynski, W. K., R. N. McElhaney, J. S. Hyde, and A. Kusumi. 2003. Molecular organization and dynamics of 1-palmitoyl-2-oleoyl phosphatidylcholine bilayer membranes containing a transmembrane α-helical peptide with hydrophobic surface roughness. Biochemistry. 42: 3939-3948.
38. Svensson-Ek, M., J. Abramson, G. Larsson, S. Törnroth, P. Brzezinski, and S. Iwata. 2002. The x-ray crystal structures of wild-type and EQ (I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides. J. Mol. Biol. 257: 3032-3038.
39. Tamm, L. K., and S. A. Tatulian. 1997. Infrared spectroscopy of proteins and peptides in lipid bilayers. Q. Rev. Biophys. 30: 365-429. (Pubitemid 28260614)
40. Verkleij, A. J., R. F. Zwaal, B. Roelofsen, P. Comfurius, D. Kastelijn, and L. L. van Deenen. 1973. The asymmetric distribution of phospholipids in the human red cell membrane. Biochim. Biophys. Acta. 323: 178-193.
41. von Heijne, G. 1994. Membrane proteins: from sequence to structure. Annu. Rev. Biophys. Biomol. Struct. 23: 167-192.
42. Yeagle, P. L. 1993. The Membranes of Cells. Academic Press, San Diego.
43. Zhang, W., M. Bogdanov, J. Pi, A. J. Pittard, and W. Dowhan. 2003. Reversible topological organization within a polytopic membrane protein is governed by a change in membrane phospholipid composition. J. Biol. Chem. 278: 50128-50135. (Pubitemid 37548850)
44. Zhang, Y.-P., R. N. A. H. Lewis, R. S. Hodges, and R. N. McElhaney. 1992a. FTIR spectroscopic studies of the conformation and amide hydrogen exchange of a peptide model of the hydrophobic transmembrane α-helices of membrane proteins. Biochemistry. 31: 11572-11578.
45. Zhang, Y.-P., R. N. A. H. Lewis, R. S. Hodges, and R. N. McElhaney. 1992b. Interaction of a peptide model of a hydrophobic transmembrane α-helical segment of a membrane protein with phosphatidylcholine bilayers: differential scanning calorimetric and FTIR spectroscopic studies. Biochemistry. 31: 11579-11588.
46. Zhang, Y.-P., R. N. A. H. Lewis, R. S. Hodges, and R. N. McElhaney. 1995a. Interaction of a peptide model of a hydrophobic transmembrane α-helical segment of a membrane protein with phosphatidylethanolamine bilayers: differential scanning calorimetric and FTIR spectroscopic studies. Biophys. J. 68: 847-857.
47. 2-amide with phosphatidylcholine bilayers. Biochemistry. 34: 2362-2371.
48. 2-amide with phosphatidylethanolamine bilayer membranes. Biochemistry. 40: 474-482.
49. Zhang, Y.-P., R. N. A. H. Lewis, and R. N. McElhaney. 1997. Calorimetric and spectroscopic studies of the thermotropic phase behavior of the n-saturated 1,2-diacylphosphatidylglycerols. Biophys. J. 72: 779-793. (Pubitemid 27044883)