Effect of Variations in the Structure of A Polyleucine-Based α-Helical Transmembrane Peptide on Its Interaction with Phosphatidylglycerol Bilayers

Biochemistry

Volumn 43, Issue 12, 2004, Pages 3679-3687

  Liu, Feng ^a   Lewis, Ruthven N A H ^a   Hodges, Robert S ^a   McElhaney, Ronald N ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; BIOLOGICAL MEMBRANES; DIFFERENTIAL SCANNING CALORIMETRY; ELECTROSTATICS; ENTHALPY; FOURIER TRANSFORM INFRARED SPECTROSCOPY; HYDROPHOBICITY; LIPIDS; PHASE TRANSITIONS;

HOMOLOGOUS SERIES; SIDE-CHAIN REACTIONS;

PROTEINS;

2,3 DIAMINOPROPIONIC ACID; ACETYLLYSYLLEUCYLLYSINAMIDE; LEUCINE; LYSINE; MEMBRANE PROTEIN; PHOSPHATIDYLGLYCEROL; POLYLEUCINE; POLYMER; TRYPTOPHAN; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; CONFORMATIONAL TRANSITION; DIFFERENTIAL SCANNING CALORIMETRY; ENTHALPY; HYDROGEN BOND; HYDROPHOBICITY; INFRARED SPECTROSCOPY; PHASE TRANSITION; PHOSPHOLIPID BILAYER; PRIORITY JOURNAL; PROTEIN INTERACTION;

CALORIMETRY, DIFFERENTIAL SCANNING; ELECTROSTATICS; HYDROPHOBICITY; LIPID BILAYERS; LYSINE; MEMBRANE PROTEINS; PEPTIDES; PHOSPHATIDYLGLYCEROLS; PROTEIN STRUCTURE, SECONDARY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE; TRYPTOPHAN;

EID: 1642279990     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi036214l     Document Type: Article

References (47)

1. Kleinschmidt, J. H. (2003) Membrane proteins-introduction. Cell. Mol. Life Sci. 60, 1527-1528.
2. White, Stephen. Membrane Proteins of known 3D structure website, University of California, Irvine, http://blanco.biomol.u-ci.edu/Membrane_Proteins_xtal.html.
3. Killian, J. A., and von Heijne, G. (2000) How proteins adapt to a membrane-water interface. Trends Biol. Sci. 25, 429-434.
4. Sandermann, H. (1978) Regulation of membrane enzymes by lipids. Biochim. Biophys. Acta 515, 209-237.
5. McElhaney, R. N. (1982) Effects of membrane lipids on transport and enzymic activities in Current Topics in Membranes and Transport (Razin, S., and Rottem, S., Eds.) Vol. 17, pp 317-380, Academic Press, New York.
6. McElhaney, R. N. (1985) Membrane lipid fluidity, phase state and membrane function in prokaryotic microorganisms in Membrane Fluidity in Biology (Alora, R. A., and Boggs, J. M., Eds.) Vol. 4, pp 147-208, Academic Press, New York.
7. McElhaney, R. N. (1984) The structure and function of the Acholeplasma laidlawii plasma membrane. Biochim. Biophys Acta 779, 1-42.
8. 2+)-ATPase from Acholeplasma laidlawii B membranes: dependence of enzyme activity on lipid headgroup and hydrocarbon chain structure. J. Biol. Chem. 264, 11598-11604.
9. Matsumoto, K. (2001) Dispensable nature of phosphatidylglycerol in Escherichia coli: dual roles of anionic phospholipids. Mol. Microbiol. 39, 1427-1433.
10. van Klompenburg, W., Ridder, A. N., van Raalte, A. L., Killian, J. A., von Heijne, G., and de Kruijff, B. (1997) In vitro membrane integration of leader peptidase depends on the Sec machinery and anionic phospholipids and can occur posttranslationally. FEBS Lett. 413, 109-114.
11. Gennis, R. B. (1989) Membrane dynamics and protein-lipid interactions, in Biomembranes: Molecular Structure and Function. Springer-Verlag, pp 166-198, New York.
12. Selinsky, B. S. (1992) Protein-lipid interactions and membrane function, in The Structure of Biological Membranes (Yeagle, P., Eds.) pp 603-651, CRC Press, Boca Raton, FL
13. Marsh, D., and Horváth, L. I. (1998) Structure, dynamics and composition of the lipid-protein interface. Perspectives from spin-labeling. Biochim. Biophys. Acta 1376, 267-296.
14. Davis, J. H., Clare, D. M., Hodges, R. S., and Bloom, M. (1983) Interaction of a synthetic amphiphilic polypeptide and lipids in a bilayer structure. Biochemistry 22, 5298-5305.
15. de Planque, M. R. R., and Killian, J. A. (2003) Protein-lipid interactions studied with designed transmembrane peptides: role of hydrophobic matching and interfacial anchoring. Mol. Mem. Biol. 20, 271-284.
16. Zhang, Y.-P., Lewis, R. N. A. H., Hodges, R. S., and McElhaney, R. N. (1992) FTIR spectroscopic studies of the conformation and amide hydrogen exchange of a peptide model of the hydrophobic transmembrane α-helices of membrane proteins. Biochemistry 31, 11572-11578.
17. Zhang, Y.-P., Lewis, R. N. A. H., Hodges, R. S., and McElhaney, R. N. (1992) Interaction of a peptide model of a hydrophobic transmembrane α-helical segment of a membrane protein with phosphatidylcholine bilayers: differential scanning calorimetric and FTIR spectroscopic studies. Biochemistry 31, 11579-11588.
18. Axelsen, P. H., Kaufman, P. H., McElhaney, R. N., and Lewis, R. N. A. H. (1995) The infrared dichroism of transmembrane helical polypeptides. Biophys. J. 69, 2770-2781.
19. Huschilt, J. C., Millman, B. M., and Davis, J. H. (1989) Orientation of alpha-helical peptides in a lipid bilayer. Biochim Biophys. Acta 979, 139-141.
20. Bolen, E. J., and Holloway, P. W. (1990) Quenching of tryptophan fluorescence by brominated phospholipid. Biochemistry 29, 9638-9643.
21. Huschilt, J. C., Hodges, R. S., and Davis, J. H. (1985) Phase equilibria in an amphiphilic peptide-phospholipid model membrane by deuterium nuclear magnetic resonance difference spectroscopy. Biochemistry 24, 1377-1386.
22. Morrow, M. R., Huschilt, J. C., and Davis, J. H. (1985) Simultaneous modeling of phase and calorimetric behavior in an amphiphilic peptide/phospholipid model membrane. Biochemistry 24, 5396-5406.
23. Zhang, Y.-P., Lewis, R. N. A. H., Hodges, R. S., and McElhaney, R. N. (1995) Interaction of a peptide model of a hydrophobic transmembrane α-helical segment of a membrane protein with phosphatidylethanolamine bilayers: differential scanning calorimetric and FTIR spectroscopic studies. Biophys. J. 68, 847-857.
24. 2H NMR. Eur. Biophys. J. 12, 1-11.
25. Subczynski, W. K., Lewis, R. N. A. H., McElhaney, R. N., Hodges, R. S., Hyde, J. S., and Kusumi, A. (1998) Molecular organization and dynamics of 1-palmitoyl-2-oleoyl-phosphatidylcholine bilayers containing a transmembrane α-helical peptide. Biochemistry 37, 3156-3164.
26. Subczynski, W. K., Pasenkiewicz-Gierula, McElhaney, R. N, Hyde, J. S., and Kusumi, A. (2003) Molecular organization and dynamics of 1-palmitoyl-2-oleoyl phosphatidylcholine bilayer membranes containing a transmembrane α-helical peptide with hydrophobic surface roughness. Biochemistry 42, 3939-3948.
27. 31P NMR spectroscopic study of the effect of transmembrane α-helical peptides on the lamellar/ reversed hexagonal phase transition of phosphatidylethanolamine model membranes. Biochemistry 40, 760-768.
28. Liu, F., Lewis, R. N. A. H., Hodges, R. S., and McElhaney, R. N. (2002). Effect of variations in the structure of a polyleucine-based α-helical transmembrane peptide on its interaction with phosphatidylcholine bilayers. Biochemistry 41, 9197-9207.
29. Segrest, J. P., De Loof, H., Dohlman, J. G., Brouillette, C. G., and Anantharamaiah, G. M. (1990) Amphipathic helix motif: classes and properties. Proteins: Struct. Funct. Genet. 8, 103-117.
30. Monne, M., Nilsson, I., Johansson, M., Elmhed, N., and van Heijne, G. (1998) Positively and negatively charged residues have different effects on the position in the membrane of a model transmembrane helix. J. Mol. Biol. 284, 1177-1183.
31. von Heijne, G. (1994) Membrane proteins: from sequence to structure. Annu. Rev. Biophys. Biomol. Struct. 23, 167-192.
32. de Planque, M. R. R., Bonev, B. B., Demmers, J. A. A., Greathouse, D. V., Koeppe, R. E., II, Separovic, F., Watts, A., and Killian, J. A. (2003) Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic Matching effects in peptide-lipid interactions. Biochemistry 42, 5341-5348.
33. 2 amide. Biochemistry 34, 2348-2361.
34. 31P NMR spectroscopic studies. Biochemistry 24, 2440-2446.
35. Zhang, Y.-P., Lewis, R. N. A. H., and McElhaney, R. N. (1997) Calorimetric and spectroscopic studies of the thermotropic phase behavior of the n-saturated 1,2-diacyl-phosphatidylglycerols. Biophys. J. 72, 779-793.
36. 2-amide with phosphatidylcholine bilayers. Biochemistry 34, 2362-2371.
37. Lewis, R. N. A. H., and McElhaney, R. N. (1996) FTIR spectroscopy in the study of hydrated lipids and lipid bilayer membranes in Infrared Spectroscopy of Biomolecules (Mantsch, H. H., and Chapman, D., Eds.) pp 159-202, John Wiley and Sons, New York.
38. 13C=O-labeled phospholipids hydrogen bonding to carbonyl groups. Biochemistry 27, 8239-8249.
39. Lewis, R. N. A. H., McElhaney, R. N., Pohle, W., and Mantsch, H. H. (1994) The components of the carbonyl stretching band in the infrared spectra of hydrated 1,2-diacylglycerolipid bilayers: a reevaluation. Biophys. J. 67, 2367-2375.
40. McElhaney, R. N. (1986) Differential scanning calorimetric studies of lipid-protein interactions in model membrane systems. Biochim. Biophys. Acta 864, 361-421.
41. Lewis, R. N. A. H., and MeElhaney, R. N. (1992) The mesomorphic phase behavior of lipids bilayers in The Structure of Biological Membranes (Yeagle, P. L., Ed.) pp 73-155, CRC Press, Boca Raton, Florida, 1992.
42. Lewis, R. N. A. H., Pohle, W., and McElhaney, R. N. (1997) The interfacial structure of phospholipid bilayers: Differential scanning calorimetry and Fourier transform infrared spectroscopic studies of 1,2-dipalmitoyl-sn-glycero-3-phosphorylcholine and its dialkyl and acyl-alkyl analogues. Biophys. J. 70, 2736-2746.
43. Dougherty, D. A. (1996) Cation-π interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp. Science 271, 163-168.
44. Sussman, J. L., Harel, M., Frolow, F., Oefner, C., Goldman, A., Toker, L., and Silman, I. (1991) Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein. Science 253, 872-879.
45. Unwin, N. (1993) Nicotinic acetylcholine receptor at 9 A resolution. J. Mol. Biol. 229, 1101-1124.
46. Satin, J., Kyle, J. W., Chen, M., Bell, P., Cribbs, L. L., Fozzard, H. A., and Rogart, R. B. (1992) A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties. Science 256, 1202-1205.
47. Yau, W.-M., Wimley, W. C., Gawrisch, K., and White, S. H. (1998) The preference of tryptophan for membrane interfaces. Biochemistry 37, 14713-14718.