Leukemic transformation of donor cells: Is it possible?

Terapevticheskii Arkhiv

Volumn 76, Issue 7, 2004, Pages 28-34

  Vinogradova, O N ^a   Savchenko, V G ^a   Domracheva, E V ^a   Parovichnikova, E N ^a   Dyachenko, L V ^a   Alimova, G A ^a   Mendeleeva, L P ^a   Lyubimova, L S ^a   Sokolov, A N ^a   Zhelnova, E I ^a   Pokrovskaya, O S ^a  

^a NONE

Author keywords

Bone marrow transplantation; Chimerism; Donor cells; FISH; Leukemia; Standard cytogenetics

Indexed keywords

ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; CELL POPULATION; CENTROMERE; CORRELATION ANALYSIS; CYTOGENETICS; DIAGNOSTIC ERROR; FLUORESCENCE IN SITU HYBRIDIZATION; GENOTYPE; HOST CELL; HUMAN; KARYOTYPE 46,XX; KARYOTYPING; LEUKEMIA; MITOSIS RATE; PROMYELOCYTIC LEUKEMIA; QUANTITATIVE ANALYSIS; RECURRENCE RISK; SENSITIVITY ANALYSIS; SEX ROLE; TRANSLOCATION LINE; TUMOR CELL; X CHROMOSOME; Y CHROMOSOME; ADULT; ALLOTRANSPLANTATION; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL TRANSFORMATION; CHEMISTRY; FEMALE; GENETICS; HISTOCOMPATIBILITY; MALE; MYELOID LEUKEMIA; PATHOLOGY; RECURRENT DISEASE;

ADULT; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOMES, HUMAN, X; CHROMOSOMES, HUMAN, Y; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, MYELOID; LEUKEMIA, PROMYELOCYTIC, ACUTE; MALE; RECURRENCE; TRANSPLANTATION CHIMERA; TRANSPLANTATION, HOMOLOGOUS;

EID: 16644369807     PISSN: 00403660     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Cooley L. D., Sears D. A., Udden M. M. et al. Donor cell leukemia: report of a case occurring 11 years after allogeneic bone marrow transplantation and review of the literature. Am. J. Hematol. 2000; 63: 46-53.
2. Heinze B., Arnold R., Rutzen-Loesevitz L., Fliedner T. M. The role of stable chromosome aberrations as biological indicators of radiation effect: studies in patients after total body irradiation and bone marrow transplantation. Stem Cells 1995; 13 (1): 191-198.
3. Au W. Y., Chan E. C., Siu L. L. Leukaemic relapse of donor origin after allogeneic bone marrow transplantation from a donor who later developed bronchogenic carcinoma. Br. J. Haematol. 2002; 119 (3): 777-780.
4. McCann S. R., Lawler M., Bacigalupo A. Recurrence of Philadelphia chromosome-positive leukemia in donor cells after bone marrow transplantation for chronic granulocytic leukemia. Leukemia and Lymphoma 1993; 10 (6): 419-425.
5. Lawler M., Locasciulli A., Longoni D. et al. Leukaemic transformation of donor cells in a patient receiving a second allogeneic bone marrow transplant for severe aplastic anaemia. Bone Marrow Transplant. 2002; 29 (5): 453-456.
6. McCann S. R., Lawler M., Gardiner N. et al. Donor leukemia following allogeneic bone marrow transplantation. Leukemia 1994; 8 (1): 133-135.
7. Van Dekken H., Hagenbeek A., Bauman J. G. Detection of host cells following sex-mismatched bone marrow transplantation by fluorescent in situ hybridization with a Y-chromosome specific probe. Leukemia 1989; 3 (10): 724-728.
8. Mitelman F., ed. ISCN (1995) Recommendations of the International Standing Committee on Human Cytogenetic Nomenclature. Basel: S. Karger; 1995.
9. Palka G., Stuppia L., Bartolomeo P. et al. FISH detection of mixed chimerism in 33 patients submitted to bone marrow transplantation. Bone Marrow Transplant. 1996; 17: 231-236.
10. Mitelman F. Cancer cytogenetics. New York; 1995.
11. Groupe Francais de Cytogenetique Hematologique. Cancer Genet. Cytogenet. 1990; 44: 169-179.
12. Fialkow P. J., Thomas E. D., Bryant J. I., Neiman P. E. Leukemic transformation of engrafted human marrow cells in vivo. Lancet 1972; 1: 1310-1313.
13. Anastasi J., Thangavelu M., Vardiman J. W. et al. Interphase cytogenetic analysis detects minimal residual disease in a case of acute lymphoblastic leukemia and resolves the question of origin of relapse after allogeneic bone marrow transplantation. Blood 1991; 77 (5): 1087-1091.
14. Spinelli O., Giussani U., Borleri G. et al. Need for an accurate molecular diagnosis to assess the donor origin of leukemia relapse after allogeneic stem cell transplantation. Haematologica 2000; 85 (11): 1153-1157.
15. Hambach L., Eder M., Dammann E. et al. Donor cell-derived acute myeloid leukemia developing 14 months after matched unrelated bone marrow transplantation for chronic myeloid leukaemia. Bone Marrow Transplant. 2001; 28 (7): 705-707.
16. Gopcsa L., Barta A., Banyai A. et al. Acute myeloid leukaemia of donor cell origin developing 5 years after allogeneic bone marrow transplantation for chronic myeloid leukaemia. Bone Marrow Transplant. 2002; 29 (5): 449-452.
17. Au W. Y., Lam C. C., Lie A. K. et al. T-cell large granular lymphocyte leukemia of donor origin after allogeneic bone marrow transplantation. Am. J. Clin. Pathol. 2003; 120 (4): 626-630.